A5065377609- Coronary Artery Anomalies
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Vascular anomalies and interventions
- Cardiac Imaging and Diagnostics
- Connective tissue disorders research
- Congenital heart defects research
- RNA modifications and cancer
- Pulmonary Hypertension Research and Treatments
- Tracheal and airway disorders
- Liver Disease and Transplantation
- Cardiovascular Effects of Exercise
- Genomics and Rare Diseases
- Cardiac tumors and thrombi
- Williams Syndrome Research
- Nuclear Structure and Function
- Liver Disease Diagnosis and Treatment
- Neurogenetic and Muscular Disorders Research
- Pericarditis and Cardiac Tamponade
- Cardiac pacing and defibrillation studies
- Kawasaki Disease and Coronary Complications
Beijing Anzhen Hospital
2009-2025
Capital Medical University
2007-2025
PLA Navy General Hospital
2014
Second Affiliated Hospital of Zhejiang University
2009
University of Cagliari
2009
Hospital de Egas Moniz
2009
National Natural Science Foundation of China
2009
Objective: To investigate the clinical manifestations, treatment, and outcomes of Barth syndrome (BTHS). Methods: A retrospective analysis was conducted on 21 pediatric patients diagnosed with BTHS between January 2010 December 2023 at Beijing Children's Hospital, Anzhen JingDu Hospital. Clinical data including gender, age onset, initial symptoms, personal history, family genetic laboratory tests (neutrophil count, echocardiography, electrocardiogram testing) were reviewed. Results: All...
Background The anomalous origin of the left coronary artery (LCA) from pulmonary (ALCAPA) and congenital main atresia (CLMCA-A) are two kinds very rare heart diseases which affect function profoundly. This study aimed to retrospectively illustrate clinical features therapy experience ALCAPA CLMCA-A patients. Methods From April 1984 July 2012, in Beijing Anzhen Hospital, 23 patients were diagnosed with 4 CLMCA-A. We summarized data 27 cases analyzed manifestation, diagnosis, treatments these...
Background: Restrictive cardiomyopathy (RCM) is the least common in which walls are rigid and heart restricted from stretching filling properly. Cardiac troponin I (cTnI) mutation-caused myofibril Ca2+ hypersensitivity has been shown to be associated with impaired diastolic function. This study aimed investigate linkage between genotype clinical therapy of RCM. Methods: Five sporadic pediatric RCM patients confirmed by echocardiography were enrolled this study. Whole-exome sequencing (WES)...
To summarize the clinical manifestations, experiences in diagnosis and treatment of arrhythmogenic cardiomyopathy (ACM) children.
Pulmonary stenosis is common in children with complex congenital heart diseases. Proper management of this problem, especially postoperatively, still controversial. This study was designed to assess the rate and determinants success or failure balloon angioplasty for such lesions.Clinical hemodynamic data from 40 pediatric patients (24 boys 16 girls) diseases who underwent were reviewed retrospectively January 2012 December 2016. Patients divided into four groups according site stenosis,...
Left main coronary artery atresia (LMCAA) is an extremely rare abnormality and only <100 cases have been reported worldwide. We describe the clinical manifestations, imaging features, prognosis, treatments of LMCAA who were admitted in our department, which aimed to improve diagnosis children.A retrospective study identified 12 patients diagnosed with congenital left at Pediatric Heart Center Beijing Anzhen Hospital from June 2010 2019. The characteristics, data, treatment follow-up...
m p a re t h e fe u s o f b i c l metabolic changes detected by hepatic phosphorus-31 magnetic resonance spectroscopy ( 31 P MRS) with the liver damage score (LDS) and pathologic in rabbits to investigate diagnostic value of MRS acute radiation injury. METHODS:A total 30 received different doses (ranging 5-20 Gy) establish injury models.Blood biochemical tests, pathological examinations were carried out 24 after irradiation.The degree was evaluated according LDS pathology.Ten healthy served...
Objective: To analyze the gene mutations and clinical features of patients with Noonan syndrome hypertrophic cardiomyopathy. Method: Determined mutation domain in five cases diagnosed cardiomyopathy identified relationship between mutant by searching relevant articles pubmed database. Result: Three genes (PTPN11 chromosome 12, RIT1 1 RAF1 3) all had been reported to be related The MYPN, MYH6 MYBP3 also found case 2. Patients same different manifestations. Both 4 5 (c.770C>T). However,...
To analyze the clinical characteristics, treatment, and outcomes of children with complete left bundle branch block (CLBBB) mediated by maternal autoantibodies.
Background There have been few large‐scale studies on the outcomes of cardiomyopathy‐associated heart failure (HF) in infants aged <1 year. This study aimed to assess longitudinal echocardiographic with HF secondary cardiomyopathy who survived for >1 Methods and Results A prospective observational following 327 infant patients up 5 years 2 large pediatric centers Northern China between January 2010 December 2018. total 236 (72.2%) had reduced left ventricular ejection fraction (LVEF)...
Objective To analyze the echocardiographic diagnosis of left atrial isomerism, and to explore clinical prognosis such patients. Methods From January 2010 October 2018, 47 cases isomerism confirmed by echocardiography at Beijing Anzhen Hospital Affiliated Capital Medical University were collected. The features, classification, surgical treatment, analyzed retrospectively. Results Among patients with 35 (35/47, 74.5%) had complex malformations, 10 (10/47, 21.3%) simple 2 (2/47,...
Objective: To investigate the clinical characteristics and pregnancy outcomes in pregnant women with left ventricular non-compaction (LVNC). Methods: The data of seven LVNC from January 2011 to December 2021 Beijing Anzhen Hospital,Capital Medical University were retrospectively analyzed, including age, gestational age symptom first occured, history, symptoms, New York Heart Association (NYHA) cardiac function class, echocardiography, blood brain natriuretic peptide (BNP), treatment maternal...