The photo-induced azole C–H arylation was realized with a dual-catalytic copper-based system. Exceedingly mild reaction conditions at ambient temperature and visible light irradiation enabled broad scope high functional group tolerance.

In recent years, enantioselective electrocatalysis has surfaced as an increasingly-effective platform for sustainable molecular synthesis. Despite indisputable progress, strategies that allow the control of two distinct stereogenic elements with high selectivity remain elusive. contrast, we, herein, describe electrochemical cobalt-catalyzed C-H activations enable installation chiral centers along a axis levels enantio- and diastereoselectivities. The developed strategy allowed C-H/N-H...

Enantioselective electrocatalyzed C–H activations have emerged as a transformative platform for the assembly of value-added chiral organic molecules. Despite recent progress, construction multiple C(sp3)-stereogenic centers via C(sp3)–C(sp3) bond formation has thus far proven to be elusive. In contrast, we herein report an annulative activation strategy, generating Fsp3-rich molecules with high levels diastereo- and enantioselectivity. κ2-N,O-oxazoline preligands were effectively employed in...

During the past decade, photo- and electrochemical reactions proceeding via single-electron-transfer (SET) triggered radical pathways have emerged as an indispensable strategy for efficient formation of chemical bonds.

Radical additions onto olefins have surfaced as an increasingly powerful strategy for the synthesis of difunctionalized scaffolds. However, despite major advances, known approaches continue to be largely limited two manifolds, namely 1,2-difunctionalization alkenes and remote difunctionalization via hydrogen atom transfer (HAT). Herein, we describe a mechanistically distinct approach by photoinduced carbon-carbon (C-C) activation/ring-opening access γ,δ-unsaturated aldehydes from...

Enantioselective electrocatalyzed C−H activations have emerged as a transformative platform for the assembly of value-added chiral organic molecules. Despite recent progress, construction multiple C(sp3)-stereogenic centers via C(sp3)−C(sp3) bond formation has thus far proven elusive. In contrast, we herein, report an annulative activation strategy, generating Fsp3-rich molecules with high levels diastereo-and enantio-selectivity. We employed novel κ2-N,O-oxazoline preligands first time in...

Chemo‐ and site‐selective functionalization of complex molecules poses a fundamental challenge. In this regard, the synergetic combination photoexcitation with electron transfer by anodic oxidation bears unique potential for novel reaction manifolds that go beyond individual photo‐ or electrochemistry.[1‐3] Herein, we introduce resource‐economic photoelectrocatalysis strategy to enable versatile direct fluoroalkylations catalyzed Earth‐abundant iron paired hydrogen evolution (HER). Notably,...

Chemo‐ and site‐selective functionalization of complex molecules poses a fundamental challenge. In this regard, the synergetic combination photoexcitation with electron transfer by anodic oxidation bears unique potential for novel reaction manifolds that go beyond individual photo‐ or electrochemistry.[1‐3] Herein, we introduce resource‐economic photoelectrocatalysis strategy to enable versatile direct fluoroalkylations catalyzed Earth‐abundant iron paired hydrogen evolution (HER). Notably,...

Abstract Plastics are omnipresent in our everyday life, and accumulation of post‐consumer plastic waste environment represents a major societal challenge. Hence, methods for recycling high demand future circular economy. Specifically, the degradation polymers towards value‐added small molecules constitutes sustainable strategy carbon Despite recent advances, chemical polymer continues to be largely limited redox agents or low energy efficiency photochemical processes. We herein report...

Abstract The demand for commodity plastics reaches unprecedented dimensions. In contrast to the well‐developed plethora of methods polymer synthesis, sustainable strategies end‐of‐life management continue be scarce. While mechanical re‐cycling often results in downgraded materials, chemical or up‐cycling offers tremendous potential an efficient and green approach, thereby addressing precarious treatment post‐use within a circular carbon economy. Recently, electrochemistry surfaced as...

Ruthenium-catalyzed photo-induced hydroarylation at room temperature shows high functional group tolerance allowing to incorporate biorelevant motifs. Mechanistic studies provided in-depth details on the light's role generate active catalyst.

The position-selective C-H bond activation of arenes has long been a challenging topic. Herein, we report an expedient ruthenium-electrocatalyzed site-selective

Abstract Radikalische Additionsreaktionen an Olefine haben sich als eine zunehmend leistungsfähige Strategie für die Synthese von difunktionalisierten Verbindungen entwickelt. Trotz signifikanter Fortschritte sind bekannten Methoden weitgehend auf zwei Ansätze beschränkt, welche entweder 1,2‐Difunktionalisierung Alkenen oder distale Funktionalisierung mittels Wasserstoffatomtransfer (HAT) verfolgen. In dieser Arbeit wird nun photoinduzierte Kohlenstoff‐Kohlenstoff...

Abstract In den letzten Jahren hat sich die enantioselektive Elektrokatalyse zunehmend als eine effektive Methode für nachhaltige molekulare Synthese herausgestellt. Trotz unbestreitbarer Fortschritte bleiben Strategien zur Kontrolle über zwei unterschiedliche stereogene Elemente mit hoher Selektivität schwer fassbar. Im Gegensatz dazu beschreiben wir hier elektrochemische Cobalt‐katalysierte C−H‐Aktivierungen, welche Installation chiraler stereogener Zentren zusammen einer chiralen Achse...

Abstract Kunststoffe sind in unserem Alltag allgegenwärtig, und die Akkumulation von Kunststoffabfällen unserer Umwelt stellt ein großes gesellschaftliches Problem dar. Daher Methoden für das Recycling im Hinblick auf eine künftige Kreislaufwirtschaft hohem Interesse. Insbesondere der Abbau Polymeren nach Nutzung durch Verbraucher hin zu wertschöpfenden kleinen Molekülen nachhaltige Strategie Kohlenstoff‐Kreislaufwirtschaft Trotz jüngster Fortschritte ist chemische Polymerabbau wie vor...

<title>Abstract</title> Chemo- and site-selective functionalization of complex molecules poses a fundamental challenge. In this regard, the synergetic combination photoexcitation with electron transfer by anodic oxidation bears unique potential for novel reaction manifolds that go beyond individual photo- or electrochemistry.^1–3 Herein, we introduce resource-economic photoelectrocatalysis strategy to enable versatile direct fluoroalkylations catalyzed Earth-abundant iron paired...