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Sophia Schneider

ORCID: 0009-0009-0140-2750
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About
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A5073213931
Research Areas
  • Hematopoietic Stem Cell Transplantation
  • Immune cells in cancer
  • Single-cell and spatial transcriptomics
  • Renal Transplantation Outcomes and Treatments
  • Diabetes and associated disorders

University of Freiburg
 2024

 Lipocalin-2 expression identifies an intestinal regulatory neutrophil population during acute graft-versus-host disease
OPENALEX - Publications 
Marie Czech Sophia Schneider Nina Peltokangas Nadia El Khawanky Sakhila Ghimire and 30 more Geoffroy Andrieux Jan Hülsdünker Máté Krausz Michele Proietti Lukas M. Braun Tamina Rückert Marlene Langenbach Dominik Schmidt Ina V. Martin Valentin Wenger Enrique de Vega Eileen Haring Mohsen Pourjam Dietmar Pfeifer Annette Schmitt‐Graeff Bodo Grimbacher Konrad Aumann Brigitte Kircher Herbert Tilg Manuela Raffatellu Erik Thiele Orberg Georg Häcker Justus Duyster Natalie Köhler Ernst Holler David Nachbaur Melanie Boerries Romana R. Gerner Dominic Grün Robert Zeiser

Acute graft-versus-host disease (aGVHD) is a life-threatening complication of allogeneic hematopoietic cell transplantation (allo-HCT), for which therapeutic options are limited. Strategies to promote intestinal tissue tolerance during aGVHD may improve patient outcomes. Using single-cell RNA sequencing, we identified lipocalin-2 (LCN2)–expressing neutrophil population in mice with aGVHD. Transfer LCN2-overexpressing neutrophils or treatment recombinant LCN2 reduced severity, whereas the...

10.1126/scitranslmed.adi1501 article EN Science Translational Medicine 2024-02-21
 HLA antigen frequencies associated with a type II diabetic Mexican American end-stage renal disease population
OPENALEX - Publications 
Sophia Schneider Donna Y. Muirhead Camille Harrison Glenn A. Halff

10.1016/0198-8859(94)91835-x article EN Human Immunology 1994-01-01
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