- biodegradable polymer synthesis and properties
- Silicone and Siloxane Chemistry
- Aerogels and thermal insulation
- Advanced Polymer Synthesis and Characterization
- Diatoms and Algae Research
- Hydrogels: synthesis, properties, applications
- Photopolymerization techniques and applications
- Advanced Theoretical and Applied Studies in Material Sciences and Geometry
- Adsorption, diffusion, and thermodynamic properties of materials
- Innovations in Concrete and Construction Materials
- Surface Modification and Superhydrophobicity
- Catalysis and Oxidation Reactions
- Advanced Thermodynamics and Statistical Mechanics
- Recycling and utilization of industrial and municipal waste in materials production
- Advanced Battery Materials and Technologies
- Polysaccharides Composition and Applications
- Advancements in Battery Materials
- Building materials and conservation
- Material Properties and Applications
- Synthesis and properties of polymers
- Injection Molding Process and Properties
- Fiber-reinforced polymer composites
- Calcium Carbonate Crystallization and Inhibition
- Polymer Nanocomposites and Properties
- RNA Interference and Gene Delivery
Foshan University
2024
Panyu District Central Hospital
2024
Guangzhou Medical University
2024
Shenzhen University
2023
Chinese Academy of Sciences
2016
<title>Abstract</title> Oligonucleotide therapeutics, including antisense oligonucleotides (ASOs) and duplex RNAs like siRNA, saRNA miRNA, hold immense potential for treating genetic acquired diseases by modulating gene expression in a target-specific manner. However, effective delivery to extrahepatic tissues, particularly the central nervous system (CNS), remains significant challenge. While GalNAc conjugation has enabled liver-specific delivery, leading several approved siRNA drugs...
ABSTRACT Oligonucleotide therapeutics, including antisense oligonucleotides (ASOs) and duplex RNAs like siRNA, saRNA, miRNA, hold immense potential for treating genetic acquired diseases by modulating gene expression in a target-specific manner. However, effective delivery to extrahepatic tissues, particularly the central nervous system (CNS), remains significant challenge. While GalNAc conjugation has enabled liver-specific delivery, leading several approved siRNA drugs hepatic targets, CNS...