Xiaoxiao Zhu

ORCID: 0009-0009-0608-1589
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About
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Research Areas
  • MicroRNA in disease regulation
  • Occupational exposure and asthma
  • Circular RNAs in diseases
  • Autophagy in Disease and Therapy
  • Epigenetics and DNA Methylation
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Antimicrobial agents and applications
  • Cancer-related molecular mechanisms research
  • Occupational and environmental lung diseases
  • Neuroblastoma Research and Treatments
  • Infectious Encephalopathies and Encephalitis
  • Catalytic Processes in Materials Science
  • Nanoparticles: synthesis and applications
  • Peroxisome Proliferator-Activated Receptors
  • Quantum optics and atomic interactions
  • Advanced Fiber Optic Sensors
  • Atomic and Subatomic Physics Research
  • Nonlinear Optical Materials Research
  • Cannabis and Cannabinoid Research
  • Ferroptosis and cancer prognosis
  • Cancer, Hypoxia, and Metabolism
  • Cold Atom Physics and Bose-Einstein Condensates
  • Semiconductor Lasers and Optical Devices
  • Advanced Glycation End Products research
  • Neonatal and fetal brain pathology

Wenzhou Medical University
2025

Zhejiang Taizhou Hospital
2025

Qingdao University
2020-2025

Affiliated Hospital of Nantong University
2023

Nantong University
2023

Space Engineering University
2023

Dalian University
2022

Dalian University of Technology
2022

University of Massachusetts Lowell
1992

Abstract Alcohol abuse is a significant cause of global morbidity and mortality, with alcoholic liver disease (ALD) being common consequence. The pathogenesis ALD involves various cellular processes, including oxidative stress, inflammation, hepatic cell death. Recently, ferroptosis, an iron-dependent form programmed death, has emerged as potential mechanism in many diseases. However, the specific involvement regulatory mechanisms ferroptosis remain poorly understood. Here we aimed to...

10.1038/s41420-023-01608-6 article EN cc-by Cell Death Discovery 2023-08-25

Abstract Neuroblastoma (NB) is a challenging pediatric extracranial solid tumor characterized by poor prognosis and resistance to chemotherapy. Identifying targets enhance chemotherapy sensitivity in NB of utmost importance. Increasing evidence implicates long noncoding RNAs (lncRNAs) play important roles cancer, but their functional remain largely unexplored. Here, we analyzed our RNA sequencing data identified the upregulated lncRNA ZNF674-AS1 non-responsive patients. Elevated expression...

10.1038/s41419-023-06394-8 article EN cc-by Cell Death and Disease 2024-01-04

To investigate the infection of children with respiratory tract in Hangzhou from 2019 to 2023, and explore epidemiological characteristics virus before after prevalence novel coronavirus. A retrospective analysis was conducted on oral pharyngeal swabs 302,680 acute infections. Colloidal gold-based assays were used detect viral antigens, including adenovirus (ADV), influenza (FluA), B (FluB), syncytial (RSV). The detection rates different viruses statistically analyzed, comparisons made...

10.1016/j.virusres.2025.199558 article EN cc-by-nc-nd Virus Research 2025-03-13

Construction of single-crystalline hierarchical plate-like ZSM-5 crystals assisted by TMG.

10.1039/d1qi01598b article EN Inorganic Chemistry Frontiers 2022-01-01

Aim Polyhexamethylene guanidine (PHMG) is widely used as a disinfectant with broad spectra of bactericidal activity and low oral toxicity. However, inhalation PHMG can cause pulmonary injury severe fibrosis. The mechanism underlying aerosol induced fibrosis remains unclear. In this study, we aimed to examine the subchronic lung determine potential cytokines involved in fibrosis.Methods C57BL/6N mice were exposed 1.03 mg/m3 through for 3 weeks, or weeks followed by other recovery.Results...

10.1080/08958378.2020.1836091 article EN Inhalation Toxicology 2020-10-14

Extensive studies have established the correlation between long-term PM

10.1016/j.jare.2024.08.029 article EN cc-by-nc-nd Journal of Advanced Research 2024-08-01

Objective. The present study was designed to establish and evaluate an early prediction model of epilepsy after encephalitis in childhood based on electroencephalogram (ECG) clinical features. Methods. 255 patients with were randomly divided into training verification sets postencephalitic (PE) no (no-PE) according whether occurred one year discharge. Univariate multivariate logistic regression analyses used screen the risk factors for PE. identified verify a model. Results. This included...

10.1155/2023/8862598 article EN cc-by Emergency Medicine International 2023-07-13

Objective: To explore the lung damage caused by repeated inhalation of polyhexamethyleneguanidine (PHMG) disinfectant aerosol and corresponding toxicological characteristics. Methods: Thirty four-week-old mice C57BL/6N strain were randomly divided into three groups, control group, low-dose high-dose group. Each group had 5 male female mice. Lab II-level purified water was used in The PHMG generated using ultrasonic atomization aqueous solution containing PHMG. concentrations low-and groups...

10.3760/cma.j.issn.0253-9624.2020.02.016 article EN PubMed 2020-02-06

N, N-dimethylformamide (DMF) is a widely existing harmful environmental pollutant from industrial emission which can threat human health for both occupational and general populations. Epidemiological experimental studies have indicated liver as the primary target organ of DMF. However, molecular mechanism under DMF-induced hepatoxicity remains unclear. In present study, we identified that DMF could induce abnormal excessive autophagy in cells. We also showed mitochondrial dysfunction lethal...

10.2139/ssrn.4051276 article EN SSRN Electronic Journal 2022-01-01

Optical characterization of novel photocrosslinkable second-order nonlinear optical (NLO) polymers are presented. These polymer systems have been designed with moieties in the main chain. When poled and sufficiently photocrosslinked these exhibit relatively stable nonlinearity at room temperature. The linear NLO properties recently synthesized investigated. Second harmonic generation (SHG) was utilized to monitor temporal stability nonlinearity. electro-optic coefficients were measured a...

10.1117/12.637261 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 1992-12-16
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