A5032445692- Estrogen and related hormone effects
- Hydrogen's biological and therapeutic effects
- MicroRNA in disease regulation
- Polyamine Metabolism and Applications
- Plasma Applications and Diagnostics
- Reproductive System and Pregnancy
Pirogov Russian National Research Medical University
2023
Ministry of Health of the Russian Federation
2023
The anti-cancer properties of plasma-treated solutions (PTS) and their interaction with drugs are one the most popular topics in modern plasma medicine. Our research involved comparing effects four physiological saline (0.9% NaCl, Ringer's solution, Hank's Balanced Salt Solution, Solution amino acids added concentrations observed human blood) treated cold atmospheric studying combined cytotoxic effect PTS doxorubicin medroxyprogesterone acetate (MPA). Analysis studied agents on formation...
A comparative analysis of the cytostatic effects progestins (gestobutanoyl, megestrol acetate, amol, dienogest, and medroxyprogesterone acetate), glucocorticoids (hydrocortisone, dexamethasone), diclofenac on tumor cells was carried out in order to confirm their silico predicted probabilities experimentally. The results showed different sensitivity HeLa, MCF-7, Hep-2, K-562, Wi-38 cell lines progestins, glucocorticoids, diclofenac. minimum IC50 found for progestin gestobutanoyl (GB) as 18 µM...