A5028122886- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Bacterial Identification and Susceptibility Testing
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Breast Lesions and Carcinomas
- Plant Pathogens and Fungal Diseases
- Global Health and Epidemiology
- Streptococcal Infections and Treatments
- Cervical Cancer and HPV Research
- Diverse Scientific Research Studies
- Diagnosis and treatment of tuberculosis
- HIV, Drug Use, Sexual Risk
- Nail Diseases and Treatments
- Adrenal Hormones and Disorders
- Neuroendocrine Tumor Research Advances
- Antifungal resistance and susceptibility
- Antibiotics Pharmacokinetics and Efficacy
- Employment and Welfare Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Actinomycetales infections and treatment
- Autoimmune Bullous Skin Diseases
- Autoimmune and Inflammatory Disorders
Purbanchal University
2023
Sikkim Manipal University
2009-2022
Institute of Medical Sciences
2009-2022
Jawaharlal Nehru Medical College
2014
University Medical Center
2012
University Hospital and Clinics
2012
University of Maryland Medical Center
2012
Indiana University – Purdue University Indianapolis
2012
Indiana University School of Medicine
2012
Cleveland Clinic
2012
Changing pattern of dermatophytic infection among people Sikkim over the past few years and its recurrence rate has brought a need to do study on clinical from this part country. The objectives are discern patterns dermatophytosis, identification isolated fungi species level see recurrence. was carried out January 2015 May 2016. A total 192 samples were collected patients with findings infection. Required history taken, followed by examination lesions sample collection. processed for...
Objectives: The objectives of the present study were to identify species enterococci isolated from nosocomial infections and determine antibiotic susceptibility pattern with reference high-level aminoglycosides vancomycin. Materials Methods: Enterococci various clinical samples collected patients after 72 hours hospitalization. Various Enterococcus identified by standard methods. High-level aminoglycoside resistance vancomycin in detected disk-diffusion agar-screen Results: One hundred...
The etiological spectrum of any superficial mycosis is largely dependent on the flora in immediate environment individual. It influenced by geographic, climatic and occupational factors. study basically to formulate baseline data for species prevalence various dermatophytes patients with onychomycosis attending Central Referral Hospital, Gangtok, Sikkim.Thirty-four clinically suspected cases were subjected mycological studies.Thirty-two (94.12%) positive fungal elements direct microscopy 28...
Background: Phenotypic methods for the detection of methicillin resistance are inadequate, due to presence hetero-resistant population and dependence environmental factors that may affect phenotypic expression resistance. Aims: Present study was conducted, evaluate efficacy identification species mec-A mediated in S. aureus with polymerase chain reaction (PCR), assess prevalence Panton-Valentine leukocidin (pvl) toxin resistant (MRSA) overall S.aureus population. Materials Methods: A total...
The aim of this study was to find out the correlation between presence virulence (gelatinase [gel E], enterococcal surface protein [esp], cytolysin A [cyl A], hyaluronidase [hyl], and aggregation substance [asa1]) vancomycin-resistant genes (van van B) in enterococci, with their phenotypic expression.A total 500 isolates (250 each clinical fecal) were processed. Enterococci isolated from various samples fecal specimens colonized patients. Various determinants namely asa1, esp, hyl, gel E,...
The two major genotypic markers that distinguish community acquired (CA) from hospital (HA) methicillin resistant Staphylococcus aureus (MRSA) isolates are the architecture of mobile genetic element (SCCmec type) and presence panton valentine leukocidin (PVL) toxin. This study was conducted to determine molecular characteristics CA- HA- MRSA sensitive S. (MSSA) in Sikkim.A total 150 clinical isolated various specimens were subjected duplex (mec-A pvl gene) multiplex typing) PCR.Of isolates,...
The aim of study was to find out the potential pathogenic role virulence factors elaborated by strains vancomycin resistant enterococci (VRE) isolated from clinical samples and VRE colonizing gastrointestinal tract hospitalized patients.Enterococci were various also fecal specimens colonized patients at time admission, after 48 h 5 days admission. Various determinants detected phenotypic tests. Vancomycin susceptibility in disc diffusion agar screen method. Minimum inhibitory concentration...
Sir, A safe blood is a critical component in improving health care and preventing the spread of infectious diseases globally. Yet quality safety transfusion still concern for health-care personnel. The extent disease markers major blood-borne pathogens [hepatitis B (HBV), hepatitis C (HCV), human immunodeficiency virus (HIV), syphilis malarial parasite] was observed as with age sex distribution donor population bank tertiary hospital Gangtok during 2001-2008. Of 3735 donors, 2423...
<b>Background:</b> The aim of this study was to find out the clinical correlation between presence vancomycin-resistant genes (<i>van A</i> and <i>van B</i>) their expression as detected by phenotypic tests in colonized patients isolates. <b>Materials Methods:</b> <i>Enterococci</i> were isolated from various samples also fecal specimens at time admission, after 48 h 5 days admission. Identification species level done using standard methods. Vancomycin susceptibility disc diffusion test....
Background: This study was carried with the main objectives: (1) to find out occurrence of pulmonary mycoses in clinically suspected tuberculosis cases at central referral hospital, Tadong, Sikkim. (2) To various fungi causing cases. Methods: 200 who visited department microbiology for diagnostic microscopic examination sputum sample acid fast bacilli were included this cross sectional study, under microbiology, Sikkim Manipal institute medical sciences, over one year. Smears samples...
Background: Sikkim, India has maintained the global targets of 70% detection and 85% cure new smear positive cases since 2003; however, rate retreatment have become a matter concern.An accurate analysis their treatment outcome is needed to ascertain strengths weaknesses in management retreatment.Methods: Diagnosis, classification, chemotherapy outcomes following were noted.Treatment details updated regularly patient's final was recorded at end treatment.Annual notification conducted for as...
Thieme Medical and Scientific Publishers Private Ltd.A-12, Second Floor, Sector -2, NOIDA -201301, India
International Journal of Medicine and Public Health,2016,6,3,144-147.DOI:10.5530/ijmedph.2016.3.10Published:August 2016Type:Original ArticleSeroprevalence Hepatitis B, C, human immunodeficiency virus their risk factors in adolescents East Sikkim, a Himalayan state IndiaLuna Adhikari, Ashish Pradhan, Dheeraj Khatri Luna Adhikari1, Pradhan2, Khatri3 1Department Microbiology, Sikkim Manipal Institute Medical Sciences, Tadong, Gangtok, India. 2Department Pediatrics, 3Deptartment Medicine,...
Background: Using the marker IS6110, which is rated gold standard for molecular research of Mycobacterium tuberculosis complex (MTB),this study seeks to determine type circulating strain M (MTB). MTB genotype was determined from clinical samples patients exhibiting pulmonary and extrapulmonary at Central Referral Hospital, SMIMS, Sikkim.Methods: The PCR using IS6110 38kDa markers were used identifying isolates in LJ slants restriction fragment length polymorphism methodology number copies...
Background: Depression is considered a common mental disorder and major contributor to the global burden of disease. estimated affect 3.8% population including 5% adults 5.7% among older than 60 years, approximately 280 million people in world (WHO 2021). Major symptoms depression include depressed mood, loss concentration, feeling excessive guilt, dying thoughts, disrupted sleep, changes appetite etc. Street vending informal work that has been contributing millions living status supporting...
Background: There is a high prevalence of HIV infection in adolescents India, especially the north eastern states but awareness on blood borne viral infections among them poor.Methods: Four hundred and ninety students aged thirteen to nineteen from seven schools colleges East Sikkim were interviewed behavior related transmission their was tested for Hepatitis B surface antigen, anti-Human Immunodeficiency virus C antibodies.Results: None positive antibodies only one antigen. 6.7% gave...
Background: Studies have shown Interferon gamma release assay as an aid in diagnosing Mycobacterium tuberculosis infection, including latent infection. This study intended to evaluate the efficacy of IGRA case detection pulmonary and correlation with fluorescence microscopy chest x-ray findings. Methods: Clinically suspected patients (N=300) findings were screened by IGRA. Each patient was subjected IGRA, diagnose active well infection. Results: Overall 300 enrolled. A total 89% observed...