A5003968798- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Cancer, Hypoxia, and Metabolism
- Acupuncture Treatment Research Studies
- Pancreatic function and diabetes
- Cardiovascular Disease and Adiposity
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Endoplasmic Reticulum Stress and Disease
- Cancer-related molecular mechanisms research
- Healthcare and Venom Research
Soonchunhyang University
2020-2025
Whether and how regulatory events at the translation stage shape cellular metabolic features of thermogenic adipocytes is hardly understood. In this study, we report two hitherto unidentified cross-talk pathways between translational regulation in beige adipocytes. By analysing temporal profiles activity protein level changes during precursor-to-beige differentiation, found selective down-regulation OXPHOS component-coding mRNAs. The restricted to Complexes I, III, IV, V, coordinated with...
Adipose tissue, an organ critical for systemic energy homeostasis, is influenced by type 2 immunity in its development and function. The cytokine interleukin (IL)-4 induces the proliferation of bipotential adipocyte precursors (APs) white fat tissue primes these cells differentiation into beige adipocytes, which are specialized thermogenesis. However, underlying mechanisms have not yet been comprehensively examined. Here, we identified six microRNA (miRNA) genes upregulated upon IL-4...