A5033158053- Cardiovascular Function and Risk Factors
- Metabolomics and Mass Spectrometry Studies
- Coronary Interventions and Diagnostics
- Nitric Oxide and Endothelin Effects
- Traditional Chinese Medicine Analysis
- Healthcare and Venom Research
- Reproductive System and Pregnancy
- Pregnancy and preeclampsia studies
- Medical Research and Treatments
- Atrial Fibrillation Management and Outcomes
- Takotsubo Cardiomyopathy and Associated Phenomena
- Nutritional Studies and Diet
- Preterm Birth and Chorioamnionitis
- Endoplasmic Reticulum Stress and Disease
- Inflammasome and immune disorders
- Nicotinic Acetylcholine Receptors Study
- Plant Diversity and Evolution
- Calcium signaling and nucleotide metabolism
- Acupuncture Treatment Research Studies
- Natural product bioactivities and synthesis
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Acute Myocardial Infarction Research
- Apelin-related biomedical research
- Electron Spin Resonance Studies
- Berberine and alkaloids research
First Affiliated Hospital of Henan University
2020-2024
Zhuhai People's Hospital
2022
Jinan University
2022
Lanzhou University
2016-2019
Lanzhou University Second Hospital
2016-2019
Jiangsu University
2018
Purpose . To use in vitro and vivo models to evaluate Glechoma longituba extract provide scientific evidence for this extract’s antiurolithic activity. Materials Methods Potassium citrate was used as a positive control group. Oxidative stress (OS) markers the expression of osteopontin (OPN) kidney injury molecule‐1 (KIM‐1) were measured assess protective effects Multiple urolithiasis‐related biochemical parameters evaluated urine serum. Kidneys harvested histological examination assessment...
Objectives This study aimed to explore the effects of astragaloside IV on metabolic syndrome induced by a high-fructose/high-fat diet in rats. Methods Rats were randomized into four groups: normal control, syndrome, + intraperitoneal 0.5 mg/kg/day, and 2.0 mg/kg/day (n=30 per group) for 14 continuous days. Left ventricular functions evaluated hemodynamic echocardiographic parameters. Results Metabolic rats had thicker interventricular septum left posterior wall, accompanied higher E/A wave...
Hepatocellular carcinoma (HCC) is one of the most frequent cancers. Sinomenine (SIN) a compound derived from Sinomenium acutum. Our previous investigations have found that SIN inhibited protein kinase B (AKT) signaling to induce autophagic death tumor cells. However, whether inhibition this pathway by could impact proliferation HCC cells unknown. Thus, we applied SK-Hep-1 and used cell counting kit 8 (CCK8), lactate dehydrogenase (LDH), colony formation 5-ethynyl-20-deoxyuridine (EdU)...
Anticardiolipin antibody (aCL), an important characterization of antiphospholipid syndrome, shows intense association with vascular endothelial injury. Hyperoside is a flavonoid extracted from medicinal plants traditionally used in Chinese medicines, displaying anti-inflammatory, anti-cancer, and anti-oxidative properties various diseases. Recent studies have shifted the focus on protective effects hyperoside However, little known about mechanisms involved. In present study, we investigated...
With the massive emergence of new technologies empowered by big data and technology, four original disciplines engineering, agriculture, medicine liberal arts have to keep up with times integrate data, artificial intelligence other related contents. New came into being, focus on professional cross-cutting practical [1], but also improve quality talent training creative exploration, in near future layout higher education or a major reshuffle will come. Industrial transformation upgrading...
Objective To investigate the effect of exogenous tetrahydrobiopterin (BH4) on improving left ventricular diastolic dysfunction and association with cardiac oxidative stress in spontaneously hypertensive rats (SHR). Methods 10-week aged specific pathogen free male were divided into 4 groups: Wistar-Kyoto (WKY), WKY + BH4, SHR BH4(with 16 each group). Rats BH4 groups given 200 mg·kg-1·d-1 by lavage administration, while control received same volume sterile water. After one month...
Objectives: Astragaloside IV (ASI), which is a saponin, has been reported to enhance the activity of eNOS and scavenge reactive oxygen species. We hypothesized that diastolic dysfunction may be associated with reduced can reversed by ASI treatment. Methods: used an established model isolated caused deoxycorticosterone acetate (DOCA)-induced mild hypertension. Mice were divided into four groups: sham DOCA mice without was administrered intraperitoneal injection 0.02 mg/kg/day for 7 days....
Objectives: Left atrial (LA) size is an independent predictor of cardiovascular events.In patients with fibrillation (AF), LA enlargement also associated the occurrence and recurrence AF, but relationship between cognitive function in AF has not been reported. Methods: 297 were selected from second hospital lanzhou university, age average was 67.6 ± 8.4. According to tertiles left diameter (LAD), they divided into three groups(LAD≤33.8 mm group included 99 patients; LAD 33.9–39.7 98 LAD≥39.8...
To explore the optimal ablation index (AI) parameters for radiofrequency catheter (RA) treating atrial fibrillation (AF).Patients with AF (186) who underwent bilateral PVAI in Department of Cardiology, Zhuhai People's Hospital, Guangdong Province, from March 2018 to October 2019 and received as first-round treatment, were grouped according AI. Control group included patients (95) recommended AI (350-400 posterior wall, 400-450 non-posterior wall). Patients ablated (300-330 350-380 Recurrence...