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Contact & Profiles
Research Areas
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Dermatology and Skin Diseases
NBE Therapeutics (Switzerland)
2024
Inhibition of IL-4/IL-13 signaling has dramatically improved the treatment atopic dermatitis (AD). In many patients, however, clinical responses are slow to develop and remain modest. Indeed, some symptoms AD dependent on IL-31, which is only partially reduced by inhibition. Thus, there an unmet need for treatments that concomitantly block IL-31 pathways. We engineered NM26-2198, a bispecific tetravalent antibody designed accomplish this task. reporter cell lines, NM26-2198 inhibited with...
10.1016/j.xjidi.2024.100258
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JID Innovations
2024-01-16
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