- Multiple Myeloma Research and Treatments
- Protein Degradation and Inhibitors
- Cancer Treatment and Pharmacology
- Natural Compounds in Disease Treatment
- Artificial Intelligence in Healthcare and Education
- Neutropenia and Cancer Infections
- Histone Deacetylase Inhibitors Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Peptidase Inhibition and Analysis
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Dental Radiography and Imaging
- Advanced X-ray and CT Imaging
- Tracheal and airway disorders
University Medical Center Freiburg
2022-2025
University of Freiburg
2022-2025
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
2024
Abstract Objectives To develop a content-aware chatbot based on GPT-3.5-Turbo and GPT-4 with specialized knowledge the German S2 Cone-Beam CT (CBCT) dental imaging guideline to compare performance against humans. Methods The LlamaIndex software library was used integrate context into chatbots. Based CBCT guideline, 40 questions were posed chatbots early career senior practitioners different levels of experience served as reference. chatbots’ compared in terms recommendation accuracy...
Computed tomography (CT) is an established method for the diagnosis, staging, and treatment of multiple myeloma. Here, we investigated potential photon-counting detector computed (PCD-CT) in terms image quality, diagnostic confidence, radiation dose compared with energy-integrating CT (EID-CT).In this prospective study, patients known myeloma underwent clinically indicated whole-body PCD-CT. The quality PCD-CT was assessed qualitatively by three independent radiologists overall edge...
The established standard to ensure state-of-the-art cancer treatment is through multidisciplinary tumor boards (TBs), although resource- and time-intensive. In this validation study, the multiple myeloma (MM)-TB was reexamined, aiming validate our previous (2012-2014) results, now using TB data from March 2020 February 2021. We assessed MM-TB protocols, physicians' documentation, patient, disease, remission status, progression-free survival (PFS), overall (OS) as left-truncated times....
In recent years, there have been significant advances in the understanding and treatment of multiple myeloma (MM). Despite this progress, is still limited information on disease patients aged 50 or younger, including impact young age characteristics, treatment, outcome.
Sowohl renale als auch ossäre Komplikationen sind häufige Endorganschäden des multiplen Myeloms (MM). In der vorliegenden Arbeit erfolgt die Darstellung Therapieoptionen bei Vorliegen von nephrologischen oder ossären MM. Dazu wurde eine aktuelle Literaturrecherche internationaler Studien- bzw. Übersichtsartikel durchgeführt. Nierenschäden beim MM entstehen durch toxische Effekte freier Leichtketten, Aggregate in den Tubuli bilden und zu Funktionsstörungen führen. Dies kann akute chronische...