A5109686280- Mental Health and Psychiatry
- Medicinal Plant Pharmacodynamics Research
- Psychosomatic Disorders and Their Treatments
- Immune cells in cancer
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Surgical Simulation and Training
- Reproductive System and Pregnancy
- Schizophrenia research and treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Extracellular vesicles in disease
- Autoimmune and Inflammatory Disorders Research
- Anatomy and Medical Technology
- Health Systems, Economic Evaluations, Quality of Life
- Immunotherapy and Immune Responses
- Mental Health Research Topics
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
China Academy of Chinese Medical Sciences
2024
Abstract Rheumatoid arthritis (RA) is a chronic autoimmune disease marked by synovitis and cartilage destruction. The active compound, icariin (ICA), derived from the herb Epimedium, exhibits potent anti-inflammatory properties. However, its clinical utility limited water insolubility, poor permeability, low bioavailability. To address these challenges, we developed multifunctional drug delivery system—adipose-derived stem cells-exosomes (ADSCs-EXO)-ICA to target macrophages in synovial...
Abstract Background This study explored how baseline insight predicts psychiatric hospitalization risk among 186 individuals with first-episode psychosis in coordinated specialty care (CSC). We hypothesized that insight, a potentially modifiable factor, moderates the relationship between CSC enrollment and outcomes, high stable predicting greater reductions hospitalizations lengths of stay (LOS). Design Insight was assessed using G12 item positive negative syndrome scale, categorizing...
Abnormal macrophage polarization is one of the common pathological bases various inflammatory diseases. The current research focus involves targeting macrophages to remodel their phenotype as a treatment approach for Notably, exosomes, which are predominantly phagocytosed by in vivo, naturally target these cells. Although icariin (ICA) and adipose mesenchymal stem cell exosomes exhibit regulatory potential polarization, practical application ICA impeded its water insolubility, poor...
You have accessJournal of UrologyHealth Services Research: Quality Improvement & Patient Safety II (MP33)1 May 2024MP33-06 ASSOCIATION BETWEEN CROWD-SOURCED ASSESSMENT OF TECHNICAL SKILLS (CSATSTM) AND COMPLICATIONS FOLLOWING RADICAL PROSTATECTOMY Maximilian J. Rabil, Michael Jalfon, Dylan Heckscher, Zhiqian Song, Fangyong Li, S. Leapman, and Jaime A. Cavallo RabilMaximilian Rabil , JalfonMichael Jalfon HeckscherDylan Heckscher SongZhiqian Song LiFangyong Li LeapmanMichael Leapman...
Understanding the relationship between insight, depression, and suicidality in first-episode psychosis (FEP) is crucial for improving clinical outcomes preventing suicide during early treatment stages. This longitudinal cohort study examined 264 participants enrolled coordinated specialty care (CSC) services FEP to investigate how insight depression at admission impact 6 12 months, assess depression's mediating role suicidality, evaluate persistence of over time. Regression analyses assessed...