A5015704716- Sirtuins and Resveratrol in Medicine
- Nonmelanoma Skin Cancer Studies
- Occupational and environmental lung diseases
- Epigenetics and DNA Methylation
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Herpesvirus Infections and Treatments
- Virus-based gene therapy research
- Glutathione Transferases and Polymorphisms
- Medical Imaging and Pathology Studies
Beijing Chest Hospital
2024
Capital Medical University
2024
Second Affiliated Hospital of Nantong University
2024
Nantong University
2024
Affiliated Hospital of Nantong University
2024
Cutaneous squamous cell carcinoma (CSCC) is one of the most common types skin cancer worldwide. Therefore, identification biomarkers associated with CSCC progression could aid in early detection high-risk and development novel therapeutic strategies.
Aims To investigate the performance of a combined biomarker approach using methylation status short stature homeobox 2 ( SHOX2 ) and prostaglandin E2 receptor EP4 PTGER4 genes, along with serum levels CYFRA21-1, for differential diganosis malignant pleural mesothelioma (MPM) from benign reactive mesothelial hyperplasia (RMH). Methods We analysed 48 MPM tissue or effusion cell block specimens 42 cases RMH. Real-time quantitative methylation-specific PCR was used to examine , ras association...