A5101965459- Ferroptosis and cancer prognosis
- Pancreatic and Hepatic Oncology Research
- Hepatitis B Virus Studies
- Esophageal Cancer Research and Treatment
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- RNA modifications and cancer
- Lung Cancer Diagnosis and Treatment
- Cancer Research and Treatments
- Acne and Rosacea Treatments and Effects
- Lung Cancer Treatments and Mutations
- Liver Disease and Transplantation
- Immune cells in cancer
- Phagocytosis and Immune Regulation
- Cancer, Lipids, and Metabolism
Hebei Medical University
2020-2024
Fourth Hospital of Hebei Medical University
2020-2024
Second Hospital of Shandong University
2023-2024
Hospital of Hebei Province
2020
Qiqihar Medical University
2014
Abstract Gut microbiota plays a crucial role in gastrointestinal tumors. Additionally, gut microbes influence the progression of esophageal cancer. However, major bacterial genera that affect invasion and metastasis cancer remain unknown, underlying mechanisms unclear. Here, we investigated flora metabolites patients with squamous cell carcinoma found abundant Bacteroides increased secretion entry surface antigen lipopolysaccharide (LPS) into blood, causing inflammatory changes body. We...
Antiviral therapy improves the clinical outcomes of patients with HBV-related cirrhosis. In this study, we aimed to evaluate incidence rate HCC in recompensated, compensated, or decompensated cirrhosis based on latest Baveno VII criteria.
Background: Lung adenocarcinoma (LUAD) is the most common subtype of non-small-cell lung cancer (NSCLC). The aim our study was to determine prognostic risk factors and establish a novel nomogram for patients. Methods: This retrospective cohort based on Surveillance, Epidemiology, End Results (SEER) database Chinese multicenter database. We selected 22,368 eligible LUAD patients diagnosed between 2010 2015 from SEER screened them inclusion exclusion criteria. Subsequently, were randomly...
Abstract Background: To delineate the levels of serum Hepatitis B virus (HBV) RNA in patients with HBV-related hepatocellular carcinoma (HCC) and study comparisons those individuals afflicted cirrhosis. Methods: Adult diagnosed cirrhosis or HCC (initial diagnosis) were enrolled cross-sectional study. Serum HBV DNA level was quantified through a real-time polymerase chain reaction assay lower limit quantification (LLQ) 20 IU/ml. Additionally, employing fluorescence thermostatic amplification...
Qigesan (QGS) has been used to effectively treat esophageal cancer (EC) for decades in China, but the mechanism by which it suppresses EC metastasis remains unknown.In this study, we examined effects of QGS on cell mobility.Using immunohistochemistry and immunofluorescence, expression Gas6 Axl, promote tumor migration invasion, was carcinoma tissues adjacent normal from patients.Levels Gas6, Gas6/Axl complex were also ECA109 TE13 cells treated with QGS.In addition, immunofluorescent staining...
The understanding of viral transcription and replication activity in HBeAg-positive chronic hepatitis B (CHB) patients with low-level viraemia (LLV) or previous (pre-LLV) remains unclear. Our aim was to evaluate compare circulating virus (HBV) RNA levels these patient groups those achieving maintained virological response (MVR). This cross-sectional study included 147 patients: 43 the LLV group, 25 pre-LLV group 79 MVR group. Serum HBV were assessed using specific target capture combined...
Esophageal squamous cell carcinoma (ESCC) is one of the most fatal cancers worldwide. Most ESCC patients are diagnosed at an advanced stage; however, current research on in vivo animal models accurately reflecting their clinical presentation lacking. Alcohol consumption a major risk factor for and has been used several disease induction. In this study, we 4-nitroquinoline-1-oxide combination with ethanol to induce mouse model. tissues were stained hematoxylin eosin histopathological...
Ethanol is an important risk factor for esophageal squamous cell carcinoma (ESCC); however, the molecular mechanisms behind how ethanol promotes ESCC development remain poorly understood. In this study, ethanol-ESCC-associated target genes were constructed and screened using network pharmacology subjected to Kyoto Encyclopedia of Genes Genomes (KEGG) bioinformatics analysis. A mouse ethanol-exposed cancer model was with 4-nitroquinoline-1-oxide (4-NQO) assess its survival tumor lesion...
Objective To investigate the infection of Demodex among 148 students a medical technology college to provide reference for prevention and treatment demodicidosis.Methods Transparent adhesive tape method questionnaires were performed:including name,gender,household survey,facial skin condition so on.The survey results statistically analyzed by using SPSS12.0 andx2 test was used comparisons between different groups.Results The total rate 41.89％,and rates male female 46.88％ 40.52％,and 39.74％...