A5102762667- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Cardiovascular Health and Risk Factors
- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Immunotherapy and Immune Responses
- Public Health and Nutrition
- Birth, Development, and Health
- Ophthalmology and Visual Health Research
- Drug Solubulity and Delivery Systems
- RNA Interference and Gene Delivery
- Infectious Disease Case Reports and Treatments
- Biomarkers in Disease Mechanisms
- Maternal and Perinatal Health Interventions
- Protein purification and stability
- Omental and Epiploic Conditions
- Adipose Tissue and Metabolism
- Berberine and alkaloids research
- Microencapsulation and Drying Processes
- Pharmacological Effects of Natural Compounds
- Health Literacy and Information Accessibility
- interferon and immune responses
- Circular RNAs in diseases
- Thyroid Cancer Diagnosis and Treatment
- Child Nutrition and Water Access
Kunming Medical University
2025
Shenyang Pharmaceutical University
2019-2024
Xi'an University of Architecture and Technology
2024
Soochow University
2018
Novartis (China)
2014
Mongolian National University
2014
Fifth Hospital of Shijiazhuang
2014
First People's Hospital of Jingzhou
2009
University of Michigan
2006-2008
Michigan Institute of Urology
2006
No AccessJournal of UrologyAdult urology1 Apr 2006Cystectomy Delay More Than 3 Months From Initial Bladder Cancer Diagnosis Results in Decreased Disease Specific and Overall Survival Cheryl T. Lee, Rabii Madii, Stephanie Daignault, Rodney L. Dunn, Yingxi Zhang, James E. Montie, David P. Wood LeeCheryl Lee , MadiiRabii Madii DaignaultStephanie Daignault DunnRodney Dunn ZhangYingxi Zhang MontieJames Montie WoodDavid View All Author...
Nanocarrier antigen-drug delivery system interacts specifically with immune cells and provides intelligent modes to improve antigen efficiency facilitate progression. However, these nanoparticles often have weak adhesion cells, followed by insufficient cell absorption, leading a failed response. Inspired the structure function of viruses, virus-like mesoporous silica (VMSNs) were prepared simulating surface structure, centripetal-radialized spike rough topology virus co-acted toll-like...
No AccessJournal of UrologyAdult Urology1 Nov 2008Lymphovascular Invasion Urothelial Cancer in Matched Transurethral Bladder Tumor Resection and Radical Cystectomy Specimens Lakshmi P. Kunju, Li You, Yingxi Zhang, Stephanie Daignault, James E. Montie, Cheryl T. Lee KunjuLakshmi Kunju Department Pathology, University Michigan School Medicine, Ann Arbor, , YouLi You Urology, ZhangYingxi Zhang DaignaultStephanie Daignault Biostatistics, MontieJames Montie LeeCheryl View All Author...
2520^ Background: Aberrations in the MET receptor tyrosine kinase pathway occur various human malignancies (via amplification, mutation, or overexpression) driving cell proliferation, survival and metastasis. INC280 is a highly selective, oral small molecule inhibitor with preclinical activity tumor models. This dose escalation study evaluated patients (pts) dependent advanced solid tumors. Methods: In this Phase (Ph) I study, primary objective was to determine MTD recommended Ph II (RP2D),...
Introduction: The incidence and mortality rates of liver cancer are high; therefore, developing new drug delivery systems with good biocompatibility targeting has become a research hotspot. Methods: Mitoxantrone hydrochloride (MH) loaded in acidic Panax notoginseng polysaccharide III nanoparticles (MANPs) was prepared using electrostatic adsorption. This achieved by loading MH (APPN III), natural compound that exhibits anti-tumor activity. Response surface methodology used to determine the...
Although the appearance of Doxil alleviated cardiotoxicity DOX, progression-free survival patients was not prolonged compared with traditional medication regimens, and side effects such as hand-foot syndrome has occurred. In order to solve this dilemma, we have designed a novel co-delivery strategy construct co-loaded liposome berberine (BER) doxorubicin (DOX), which called LipoBeDo. The optimal synergistic ratio two drugs screened by cell cytotoxicity experiments in vitro, attenuation...
Objectives: This study investigated the impact of polymer excipients on a typical cocrystal for sacubitril (SAC) and valsartan (VAL), aiming to guide optional formulation design maximize oral bioavailability.Methods: Poly vinyl pyrrolidone (PVP) hydroxypropyl cellulose (HPC) methylcellulose (HPMC) were selected. The dissolution/permeation system was used predict both kinetics drug supersaturation simple permeation. intermolecular interaction analyzed by 1H NMR spectroscopy molecular dynamics...
Abstract Interruption of EGFR signaling, either by blocking binding sites on the extracellular domain receptor or inhibiting intracellular tyrosine kinase activity, can prevent growth EGFR-expressing tumors. inhibitors (TKIs) provide a favorable treatment outcome in mutation positive NSCLC patients. However, many patients eventually develop progressive disease after treatment. Such acquired resistance limits long-term efficacy these TKIs clinic. The mechanisms include variety mutations and...
It is crucial to improve poorly water-soluble orally administered drugs through both preclinical and therapeutic drug discovery. A co-amorphous formulation consisting of two low molecular weight (MW) molecules offers a solubility/dissolubility advantage over its crystalline form by maintaining their amorphous status. Here, we report on solid dispersion (SD) system that includes inert carriers (lactose monohydrate or microcrystalline cellulose) sacubitril (SAC)-valsartan (VAL) using the spray...
You have accessJournal of UrologyPodium, Monday, May 23, 2005, 3:30 - 5:30 pm1 Apr 2005911: Lymphovascular Invasion is an Independent Predictor Survival in CTl Bladder Cancer Cheryl T. Lee, James E. Montie, YingXi Zhang, Rodney L. Dunn, and David P. Wood LeeCheryl Lee More articles by this author , MontieJames Montie ZhangYingXi Zhang DunnRodney Dunn WoodDavid View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)35067-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack...
You have accessJournal of UrologyPodium, Monday, May 22, 2006, 1:00 - 3:00 pm1 Apr 2006887: Gender Disparities in Urologic Referral Hematuria Emilie Johnson, Stephanie Daignault, Yingxi Zhang, and Cheryl T. Lee JohnsonEmilie Johnson , DaignaultStephanie Daignault ZhangYingxi Zhang LeeCheryl View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)33123-9AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "887:...
You have accessJournal of UrologyPodium 43, Tuesday, May 22, 2007, 1:00 - 3:00 pm1 Apr 20071520: Comparison Lymphovascular Invasion in Turbt and Radical Cystectomy Specimens from Patients with Urothelial Carcinoma L. Priya Kunju, Li You, Yingxi Zhang, Stephanie Daignault, James E. Montie, Cheryl T. Lee KunjuL. Kunju More articles by this author , YouLi ZhangYingxi Zhang DaignaultStephanie Daignault MontieJames Montie LeeCheryl View All Author...