A5028176703- Bacteriophages and microbial interactions
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Bacterial Genetics and Biotechnology
- Diabetes Management and Research
- Toxin Mechanisms and Immunotoxins
- Genomics and Phylogenetic Studies
- Protein Structure and Dynamics
Institute for Basic Science
2024
Imperial College London
2010
Abstract Podophages that infect gram-negative bacteria, such as Pectobacterium pathogen ΦM1, encode tail assemblies too short to extend across the complex cell wall. To overcome this, podophages a large protein (ejectosome) packaged inside viral capsid and correspondingly ejected during infection form transient channel spans periplasmic space. Here, we describe ejectosome of bacteriophage ΦM1 resolution 3.32 Å by single-particle cryo-electron microscopy (cryo-EM). The core consists...
We assessed whether per-arnt-sim (PAS) domain-containing protein kinase (PASK) is involved in the regulation of glucagon secretion.
Podophages that infect gram-negative bacteria, such as Pectobacterium pathogen PhiM1, encode tail assemblies too short to extend across the complex cell wall. To overcome this, podophages a large protein (ejectosome) packaged inside viral capsid and correspondingly ejected during infection form transient channel spans periplasmic space. Here we describe ejectosome of bacteriophage PhiM1 resolution 3.32 angstroms by single particle cryo-EM. The core consists tetrameric octameric ejection...