Tirzepatide is a GLP1/GIP receptor agonist that used to treat type 2 diabetes and promote weight loss. Common side effects of include nausea, vomiting, diarrhea. More severe pancreatitis, cholelithiasis, thyroid cancer, cholecystitis. With the increased use these medications, additional are being discovered. Delayed gastric emptying associated with agonists can increase risk developing appendicitis due changes in gastrointestinal motility. There minimal data on Tirzepatide. This novel case...

Background: Physical examination may be inconclusive in adolescents presenting with an acute traumatic knee effusion because of pain and guarding. The purpose this study was to describe the magnetic resonance imaging (MRI) findings effusions compare injuries based on age, sex, physeal maturity. Methods: All MRIs using a trauma protocol performed at our institution over 2-year period were evaluated. One hundred thirty-one patients between ages 10 18 years age clinical history confirmed MRI...

Intraoperative blood loss in scoliosis surgery often requires transfusions. Autogenous decreases but does not eliminate risks typically associated with allogenic transfusion. Costs transfusions are significant. Tranexamic acid (TXA) has been shown to decrease cardiac and joint surgery. Few studies have examined its use pediatric spine surgery, the results inconsistent. The aim of this study was determine whether TXA intraoperative transfusion requirements adolescent idiopathic patients...

It is not uncommon to see a patient with bilateral cavovarus feet in the outpatient setting. A large percentage of these patients are subsequently diagnosed an associated condition, such as Charcot-Marie-Tooth disease. The purpose present report was determine prevalence disease children who have feet. chart review done. Patients were excluded if they had existing medical problem known be after clinical assessment by orthopaedic surgeon and neurologist. diagnosis confirmed either standard...

The aims of this study were to evaluate outcomes percutaneous epiphysiodesis, as described by Bowen, in 97 patients and assess complications determine whether the effect epiphysiodesis will accurately follow Moseley chart predictions.A total reviewed retrospectively. Fifty-six girls 41 boys, with a mean skeletal age 12.6 years (range, 10-16 years) at time operation, followed up until maturity, 3.8 1-10 years).The residual leg length discrepancy (LLD) 88 maturity was 1.3 cm 0-3.5 cm). In 9...

Posterior cruciate ligament (PCL) insertion-site osteochondral avulsions in children, particularly from the tibia, are not commonly seen by orthopaedic surgeons. Because of rarity these injuries, careful attention to specific physical examination and imaging findings with injuries is necessary so that proper diagnosis can be made. Osteochondral PCL missed on plain radiographs skeletally immature patients, therefore magnetic resonance for diagnosis. With this knowledge, clinicians formulate...

Retrospective cohort.To assess the period prevalence and predisposing factors in thoracolumbar kyphosis progression (TLK).TLK is a common presentation children with achondroplasia. This condition occurs very early life; it observed during first attempts to sit, has multifactorial etiology. Studies are limited on radiologic assessment of angle wedging deformed vertebra, but none our knowledge TLK achondroplasia.The records 48 103 achondroplasia seen between 1997 2005 were examined....

Childhood obesity is a national problem that has gained significant attention in both the medical literature and media. Obesity adult population been associated with increased failure of conservative treatments. Our hypothesis childhood loss reduction after closed treatment distal radius fractures.A total 157 patients consecutive fractures who underwent emergency department or operating room were included from office records sole pediatric orthopaedic subspecialist group metropolitan area...

Many approaches are being taken to generate cartilage replacement materials. The goal of this study was use a self-aggregating suspension culture model chondrocytes with mechanical preconditioning.Our differs from others in that it is based on scaffold-less, produces tissue analog has been shown share many similarities the natural phenotype. Owing known loaded environment under which function vivo, we hypothesized applying force culture-derived chondrocyte biomass would improve its...

Abstract Purpose This project aims to evaluate the relationship between biological sex and postoperative pain in patients receiving posterior spinal fusion for adolescent idiopathic scoliosis. Methods is a retrospective study of (n=137) aged 10-17 scoliosis 01/2018 09/2022. Each patient received surgery by same pediatric orthopedic surgeon with identical management regimen at children’s hospital or tertiary referral center spine program. Results There were no significant differences any...

Predicting patients' remaining angular growth and timing for hemiepiphysiodesis are crucial correcting coronal plane knee deformities in children. We asked whether the Angular Deformity Versus Growth Remaining Chart predicted correction of Serial orthoroentgenograms predictive chart were used to time percutaneous hemiepiphysiodesis, children followed until skeletal maturity. Twenty-five consecutive (35 extremities) with a mean age 13 years (range, 9.6-16 years) had hemiepiphysiodeses as...

We used the dynamic pedobarographs to study pressure distribution patterns in foot after surgical correction of cavovarus feet. also assessed influence ankle power generation on these Nine children (14 feet) diagnosed with Charcot-Marie-Tooth disease who had undergone operative treatment a combination osteotomies and muscle transfers were subjects this study. Preoperative postoperative pedobarographic measurements recorded included over medial forefoot, lateral midfoot (MMF), (LMF), heel...

A percutaneous supramalleolar osteotomy with multiple drill holes and closed osteoclasis was used to correct rotational deformities of the tibia in patients cerebral palsy. The technique is described results 247 limbs (160 patients) are reported. mean age at time surgery 10.7 years (4 20). radiographs were analysed for union, loss correction, angulation site osteotomy. Bone healing obtained all except one a period seven weeks (5 12). Malunion after reduction developed tibia. Percutaneous...

Retrospective cohort study.This project aims to evaluate the relationship between increased use of intraoperative nonopioid analgesics, muscle relaxers, and anesthetics postoperative outcomes, including opioid utilization, time until ambulation, hospital length stay.Adolescent idiopathic scoliosis (AIS) is a structural deformity spine that occurs in otherwise healthy adolescents, occurring with frequency 1% 3%. Up 60% patients receiving spinal surgeries, particularly posterior fusion (PSF),...

Aneurysmal bone cysts are benign active or aggressive tumors that commonly arise in the long bones, especially femur, tibia, and humerus posterior elements of spine. affect all age groups but more common before skeletal maturity (first two decades life). They usually involve metaphysis metadiaphyseal region bones. Although juxtaphyseal lesions abutting growth plate extending into epiphysis have been described, there is no report an aneurysmal cyst entirely primarily located epiphysis. We on...

The aims of this study are, first, to determine the incidence heterotopic ossification (HO) in patients with cerebral palsy (CP) who have undergone pelvic and/or proximal femoral osteotomies and, second, identify any risk factors that may contribute its development patient population. radiographs 219 consecutive CP underwent or without were reviewed. Risk including gender, age, and degree involvement, ambulatory status, previous hip operations, bilateral surgery, capsular release,...

We sought to evaluate findings of screening cardiac studies in adolescent idiopathic scoliosis (AIS) patients by reviewing the echocardiograms and electrocardiograms (EKGs) performed at their preoperative evaluation for spinal fusion.Retrospective chart review all surgical AIS from 2000 2007 was completed (n=212). Patients with neuromuscular scoliosis, known connective tissue disease, or known/suspected disease were excluded. In presurgical screening, 12 lead EKG, 2dimensional-Doppler,...

We present a case of an incidental finding dural ectasia in child diagnosed with Larsen syndrome. syndrome is rare inherited disorder connective tissue characterized by facial dysmorphism, congenital joint dislocations the hips, knees and elbows, deformities hands feet. Dural as abnormal expansion sac surrounding spinal cord may result morphologic changes, instability, spontaneous dislocation. To best our knowledge, presence has not previously been reported.A 6-year-old boy presented upper...

The aims of this study were to determine factors that cause a leg-length discrepancy (LLD) the extent correction is indicated after treatment in developmental dysplasia hip and whether LLD may be treated with percutaneous epiphysiodesis. Twelve children included study. which caused avascular necrosis, femoral shortening varus at reduction, septic arthritis. Percutaneous epiphysiodesis contralateral limb reduced mean predicted from 3.8 1.2 cm maturity. We concluded (>2.5 cm) might result...