A5033494050- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Contact Dermatitis and Allergies
- Urticaria and Related Conditions
- Robotic Path Planning Algorithms
- Robotic Locomotion and Control
- Robot Manipulation and Learning
- Cutaneous lymphoproliferative disorders research
- Nail Diseases and Treatments
- Hydraulic and Pneumatic Systems
- Immunotherapy and Immune Responses
- Chronic Lymphocytic Leukemia Research
- Maritime Navigation and Safety
- Mast cells and histamine
- Autoimmune Bullous Skin Diseases
- Robotic Mechanisms and Dynamics
- Advancements in Transdermal Drug Delivery
- Robotics and Sensor-Based Localization
- Innovations in Concrete and Construction Materials
- Prosthetics and Rehabilitation Robotics
- Herbal Medicine Research Studies
- Kruppel-like factors research
- Transgenic Plants and Applications
Shiga University of Medical Science
2003-2025
Yanmar (Japan)
2020-2024
Kyushu Institute of Technology
2024
Goodman Research Group (United States)
2019
Goodman (Japan)
2014
Fundação Universitária de Cardiologia
2014
Honda (Germany)
2006-2010
Honda (Japan)
2007-2009
Ministry of Health Labour and Welfare
2005
GTx (United States)
1997
Atopic dermatitis (AD) is a common inflammatory skin disease associated with the local infiltration of T helper type 2 (Th2) cells. The ST2 gene encodes both membrane-bound ST2L and soluble (sST2) proteins by alternative splicing. orphan receptor functionally indispensable for Th2 We found significant genetic association between AD −26999G/A single nucleotide polymorphism (SNP) (χ2-test, raw P-value=0.000007, odds ratio 1.86) in distal promoter region (chromosome 2q12) study 452 patients 636...
Atopic dermatitis (AD) is prone to exacerbations in response various triggering factors and flare-ups after remission. We searched for molecules associated with relapse/exacerbation of AD among altered gene expression the skin patients AD. Microarray analyses were performed on lesional non-lesional adolescent or adult recalcitrant healthy controls. Five chaperones involved intracellular stress responses, namely heat shock protein family A (Hsp70) member 9 (HSPA9), 90 beta 1 (HSP90B1),...
Atopic dermatitis (AD)-specific genes have not yet been clarified. Objectives To identify gene expression specific to active atopic skin lesions.We analysed 23,000 in biopsy samples from 17 patients with AD and four normal controls using Affymetrix oligonucleotide arrays.Four of the 10 greatest differences between controls, S100A8 S100A7 (upregulated), loricrin filaggrin (downregulated), were epidermal differentiation located on 1q21, a locus previously reported genetic linkage AD.Our...
To ascertain the prevalence of childhood and adolescent atopic dermatitis in a Japanese population, we clinically observed total body 5 to 6-year-old children (994 cases), 7 9-year-old (1,240 10 12-year-old (1,152 13 15-year-old (1,670 16 18-year-old adolescents (2,159 cases). The examination was performed spring 1994-96, when exacerbation most frequently occurs Japan. Atopic 24% 6-year group, 19% 9-year 15% 12-year 14% 15-year 11% 18-year group. 9 two times five as high similar age groups...
We propose a self collision avoidance system that superposes trajectories in order not only to protect the robot's hardware but also enable continuous motions. The runs real-time so robot can work an uncertain environment. It is based on virtual forces between close segments of robot. movements are blended with whole body motion control change priority target reaching and avoidance. blending performed autonomously without necessity external switching. Our method works both while standing...
Background: Mild cases of atopic dermatitis (AD) generally improve with standard treatment.However, treatment fails many patients recalcitrant AD skin lesions.Study results in animal models have demonstrated that the administration tea (ie, green, black, or oolong) has suppressed type I and IV allergic reactions.Objective: To test effectiveness oolong AD.Patients: Although 121 were enrolled study, 118 completed open study.Methods: Patients asked to maintain their dermatological they also...
Background The genetic background of atopic eczema might be heterogeneous and there is a possibility that immunoglobulin (Ig)E responsiveness in patients with controlled separately from the development eczema. Although both interleukin (IL)‐4 IL‐4 receptor α chain have an important role for IgE production are therefore possible candidate genes atopy, it has not been clarified whether these play any roles who normal productivity. Objective We aimed to assess polymorphisms gene patients,...
Summary It has been reported that a functional polymorphism in the promoter of RANTES gene (−403G/A) is associated with atopic dermatitis German population. Although there are several reports on association polymorphisms (−403G/A and −28C/G) asthma, these not yet confirmed other populations. We therefore aimed to test whether relate well‐defined Japanese conducted an study upregulating 389 patients 177 healthy control subjects. There was significant between variant −28G dermatitis, while...
We describe a new method for real-time collision avoidance humanoid robots. Instead of explicitly modifying the commands, our influences control system by means nullspace criteria and task interval. The is driven virtual force acting on joint center vector that defines minimum potential function in space. interval target constraints coordinates allows to specify deviations from given position. advantages this indirect are smooth trajectories can be achieved underlying motion may use any...
We describe a system for visual interaction developed humanoid robots. It enables the robot to interact with its environment using smooth whole body motion control driven by stabilized targets. Targets are defined as visually extracted "proto-objects" and behavior-relevant object hypotheses means of short-term sensory memory. Selection mechanisms used switch between behavior alternatives searching or tracking objects well different strategies reaching. The decision like reaching right left...
Although it has been recognized that women with atopic dermatitis often show menstrual-cycle-associated skin deterioration, information about this subject is meager.To clarify the clinical features of monthly worsening dermatitis.A total 286 Japanese were interviewed to see whether menstrual cycle had any influence upon their lesions, and they symptoms premenstrual syndrome. Patients suffering from deterioration then observed during after worsening.Of patients interviewed, 134 (47%) most...
Abstract Although it is well known that patients with atopic dermatitis often show unpredictable, irregular aggravation of skin lesions, there are no previously published studies examining trigger factors for such unpredictable aggravation. We investigated whether foods play a role in the worsening dermatitis. The patient group included 195 Japanese adult who showed lesions. They were hospitalized and openly challenged suspected foods. Photographs representative lesion sites taken at...
ABSTRACT Atopic dermatitis is a common inflammatory skin disease that especially affects children and adolescents. Many environmental factors have been recognized as relevant in aggravating lesions of the disease. However, it remains to be determined whether foods play role worsening with atopic dermatitis. In present study, we investigated irregular aggravation The study population consisted 69 patients aged 3–15 years They were hospitalized open challenge tests performed suspected foods....
Ninety-two exclusively breast-fed Japanese infants with atopic dermatitis were studied to see whether tree nut-related foods (chocolate and coffee) fermented (cheese, yogurt, bread, soy sauce, miso soup beans) eaten by their mothers affected skin condition. Of the 92 infants, 67 (73%) showed improvement of lesions when avoided these aggravation reintroduced. The predominant offending chocolate, sauce soup. A long-term maternal exclusion trigger brought about progressive in majority infants....