A5016758719- Esophageal Cancer Research and Treatment
- Global Cancer Incidence and Screening
- Esophageal and GI Pathology
- Cancer survivorship and care
- PI3K/AKT/mTOR signaling in cancer
- Health Systems, Economic Evaluations, Quality of Life
- Liver physiology and pathology
- Cytokine Signaling Pathways and Interactions
- Ferroptosis and cancer prognosis
- Palliative Care and End-of-Life Issues
- MRI in cancer diagnosis
- Apelin-related biomedical research
- Fibroblast Growth Factor Research
- Neurological Disease Mechanisms and Treatments
- Synthesis and biological activity
- Neurogenesis and neuroplasticity mechanisms
- Health and Wellbeing Research
- S100 Proteins and Annexins
- Peptidase Inhibition and Analysis
- Hepatocellular Carcinoma Treatment and Prognosis
- Cell Adhesion Molecules Research
- Dementia and Cognitive Impairment Research
- Immunotherapy and Immune Responses
- Frailty in Older Adults
- Lung Cancer Treatments and Mutations
Temple University
2023-2025
Temple University Hospital
2025
University of Southern California
2018
University of California, San Diego
2016-2017
Abstract Purpose To examine racial and ethnic disparities in Health-Related Quality of Life (HRQOL) older adults with breast cancer, both pre- post-diagnosis. Methods Using the SEER-MHOS database, we included patients ≥ 65 years old cancer who completed Health Outcomes Survey within 24 months post-diagnosis, were non-Hispanic White, Asian or Pacific Islander, Black African American, Hispanic. HRQOL data was measured via Physical Mental Component Summary (PCS, MCS). Univariable multivariable...
LDL receptor-related proteins (LRPs) are transmembrane receptors involved in endocytosis, cell-signaling, and trafficking of other cellular proteins. Considerable work has focused on LRPs the fields vascular biology neurobiology. How these affect cancer progression humans remains largely unknown. Herein, we mined provisional databases The Cancer Genome Atlas (TCGA) to compare expression thirteen ten common solid malignancies patients. Our first goal was determine abundance LRP mRNAs each...
In high grade glioma (HGG), extensive tumor cell infiltration of normal brain typically precludes identifying effective margins for surgical resection or irradiation. Pertussis toxin (PT) is a multimeric complex that inactivates diverse Gi/o G-protein coupled receptors (GPCRs). Despite the broad continuum regulatory events controlled by GPCRs, PT may be applicable as therapeutic. We have shown urokinase receptor (uPAR) major driver HGG migration. uPAR-initiated cell-signaling requires GPCR,...
<div>AbstractBackground:<p>It is unclear whether health-related quality of life (HRQOL) disparities exist between racial/ethnic groups in older patients with esophageal cancer, pre- and post-diagnosis.</p>Methods:<p>Using the SEER-MHOS (Surveillance, Epidemiology, End Results Medicare Health Outcomes Survey) national database, we included ages 65-years-old or greater cancer diagnosed from 1996 to 2017. HRQOL data within 36 months before after diagnosis were measured...
<p>Distribution of the SEER-MHOS Linked Data Resource (1998-2021)</p>
<p>Distribution of the SEER-MHOS Linked Data Resource (1998-2021)</p>
<div>AbstractBackground:<p>It is unclear whether health-related quality of life (HRQOL) disparities exist between racial/ethnic groups in older patients with esophageal cancer, pre- and post-diagnosis.</p>Methods:<p>Using the SEER-MHOS (Surveillance, Epidemiology, End Results Medicare Health Outcomes Survey) national database, we included ages 65-years-old or greater cancer diagnosed from 1996 to 2017. HRQOL data within 36 months before after diagnosis were measured...
<p>Distribution of the SEER-MHOS Linked Data Resource (1998-2021)</p>
<p>Distribution of the SEER-MHOS Linked Data Resource (1998-2021)</p>
<div>AbstractBackground:<p>It is unclear whether health-related quality of life (HRQOL) disparities exist between racial/ethnic groups in older patients with esophageal cancer, pre- and post-diagnosis.</p>Methods:<p>Using the SEER-MHOS (Surveillance, Epidemiology, End Results Medicare Health Outcomes Survey) national database, we included ages 65-years-old or greater cancer diagnosed from 1996 to 2017. HRQOL data within 36 months before after diagnosis were measured...