Matthew J. Farrell

ORCID: 0000-0003-4810-6253
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About
Contact & Profiles
Research Areas
  • Esophageal Cancer Research and Treatment
  • Global Cancer Incidence and Screening
  • Esophageal and GI Pathology
  • Colorectal Cancer Surgical Treatments
  • Lung Cancer Research Studies
  • Neuroendocrine Tumor Research Advances
  • Advances in Oncology and Radiotherapy
  • Cancer survivorship and care
  • Palliative Care and End-of-Life Issues
  • Colorectal and Anal Carcinomas
  • Lung Cancer Treatments and Mutations
  • Radiomics and Machine Learning in Medical Imaging
  • Management of metastatic bone disease
  • Frailty in Older Adults
  • Health Systems, Economic Evaluations, Quality of Life
  • Prostate Cancer Diagnosis and Treatment
  • Advanced Radiotherapy Techniques
  • Radio Frequency Integrated Circuit Design
  • Colorectal Cancer Screening and Detection
  • Prostate Cancer Treatment and Research
  • Empathy and Medical Education
  • Medical Education and Admissions
  • Lung Cancer Diagnosis and Treatment
  • Sex work and related issues
  • Clinical Reasoning and Diagnostic Skills

University of California, Los Angeles
2023-2025

Radiation Oncology Associates
2025

Oregon Health & Science University
2017-2023

Providence St. Vincent Medical Center
2020

The surrogacy of biochemical recurrence (BCR) for overall survival (OS) in localized prostate cancer remains controversial. Herein, we evaluate the BCR using different analytic methods.Individual patient data from 11 trials evaluating radiotherapy dose escalation, androgen deprivation therapy (ADT) use, and ADT prolongation were obtained. Surrogate candidacy was assessed Prentice criteria (including landmark analyses) two-stage meta-analytic approach (estimating Kendall's tau R2)....

10.1200/jco.23.00617 article EN Journal of Clinical Oncology 2023-08-28

10.1001/jama.2024.25606 article DE JAMA 2025-03-05

Abstract Purpose To examine racial and ethnic disparities in Health-Related Quality of Life (HRQOL) older adults with breast cancer, both pre- post-diagnosis. Methods Using the SEER-MHOS database, we included patients ≥ 65 years old cancer who completed Health Outcomes Survey within 24 months post-diagnosis, were non-Hispanic White, Asian or Pacific Islander, Black African American, Hispanic. HRQOL data was measured via Physical Mental Component Summary (PCS, MCS). Univariable multivariable...

10.1186/s12955-025-02359-x article EN cc-by Health and Quality of Life Outcomes 2025-03-26

Residency applicants have long been advised to play it safe in their personal statement, but what if the best way rise above heap is share a part of yourself you've told keep hidden?

10.1056/nejmp2414494 article EN New England Journal of Medicine 2025-03-29

Background: Watchful waiting in rectal cancer patients with a complete clinical response (cCR) to chemoradiation therapy (CRT) forgo upfront resection has been proposed. Growing evidence suggests that watch-and-wait approach using for salvage of local recurrence may improve quality life without jeopardizing outcomes. The current acceptance by US radiation oncologists (ROs) is unknown. Methods: ROs completed our IRB-approved anonymous e-survey regarding non-surgical management who achieved...

10.21037/jgo.2018.08.02 article EN cc-by-nc-nd Journal of Gastrointestinal Oncology 2018-11-29

10.1200/jco.22.02611 article EN Journal of Clinical Oncology 2023-03-28

Management of rectal cancer with involved lateral pelvic lymph nodes (LPLNs) at the time diagnosis-the stage we refer institutionally to as Stage 3.5-is controversial. The American Joint Committee on Cancer's 7th edition classifies internal iliac (LNs) regional (Stage III), but both external and common LNs metastatic IV). However, in many Asian countries all LPLNs are considered patients treated curative intent, literature supporting improved outcomes LPLN dissection. patterns these by US...

10.21037/jgo.2018.02.05 article EN cc-by-nc-nd Journal of Gastrointestinal Oncology 2018-05-25

Accurate staging is crucial for management of patients with newly diagnosed rectal cancer. Endorectal ultrasound (EUS) has been the standard modality in United States decades, magnetic resonance imaging (MRI) now preferred by national guidelines. Positron emission tomography (PET), conversely, not recommended. The current utilization modalities American radiation oncologists cancer unknown.American completed an anonymous institutional review board-approved online survey probing their...

10.21037/jgo.2018.01.19 article EN cc-by-nc-nd Journal of Gastrointestinal Oncology 2018-05-25

10.1200/jco.20.01146 article EN Journal of Clinical Oncology 2020-08-04

<div>AbstractBackground:<p>It is unclear whether health-related quality of life (HRQOL) disparities exist between racial/ethnic groups in older patients with esophageal cancer, pre- and post-diagnosis.</p>Methods:<p>Using the SEER-MHOS (Surveillance, Epidemiology, End Results Medicare Health Outcomes Survey) national database, we included ages 65-years-old or greater cancer diagnosed from 1996 to 2017. HRQOL data within 36 months before after diagnosis were measured...

10.1158/1055-9965.c.7061337 preprint EN 2024-02-06

<div>AbstractBackground:<p>It is unclear whether health-related quality of life (HRQOL) disparities exist between racial/ethnic groups in older patients with esophageal cancer, pre- and post-diagnosis.</p>Methods:<p>Using the SEER-MHOS (Surveillance, Epidemiology, End Results Medicare Health Outcomes Survey) national database, we included ages 65-years-old or greater cancer diagnosed from 1996 to 2017. HRQOL data within 36 months before after diagnosis were measured...

10.1158/1055-9965.c.7061337.v1 preprint EN 2024-02-06
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