A5102762509- Soil Carbon and Nitrogen Dynamics
- Nanoparticles: synthesis and applications
- Microbial Community Ecology and Physiology
- Gut microbiota and health
- Carbon and Quantum Dots Applications
- Advanced Nanomaterials in Catalysis
- Graphene and Nanomaterials Applications
- Legume Nitrogen Fixing Symbiosis
- Genetics and Neurodevelopmental Disorders
- Autoimmune Neurological Disorders and Treatments
- Extracellular vesicles in disease
- Insect Pest Control Strategies
- Evolutionary Game Theory and Cooperation
- Breastfeeding Practices and Influences
- Mechanical and Thermal Properties Analysis
- Inflammasome and immune disorders
- Neurobiology and Insect Physiology Research
- Nanocluster Synthesis and Applications
- Protist diversity and phylogeny
- Solar-Powered Water Purification Methods
- Nanoplatforms for cancer theranostics
- Invertebrate Immune Response Mechanisms
- ZnO doping and properties
- Metastasis and carcinoma case studies
- Malaria Research and Control
Chinese Academy of Sciences
2023-2025
Institute of Urban Environment
2023-2025
Qilu Hospital of Shandong University
2022-2024
Northwest A&F University
2021-2023
Tianjin University of Traditional Chinese Medicine
2023
First Hospital of China Medical University
2022
China Medical University
2022
University of Hong Kong
2022
Ministry of Education of the People's Republic of China
2022
Jilin Agricultural University
2022
Alcohol overconsumption as a worldwide issue results in alcoholic liver disease (ALD), such steatosis, hepatitis, and cirrhosis. The treatment of ALD has been widely investigated but remains challenging. In this work, the protective effects graphene oxide quantum dots (GOQDs) novel nanozymes against alcohol are discovered, specific mechanisms underlying these elucidated via omics analysis. GOQDs dramatically alleviate reduction cell viability induced by ethanol can act to accelerate...
Although increasing attention has been paid to the nanotoxicity of graphene oxide quantum dots (GOQDs) due their broad range applications, persistence and recoverability associated with GOQDs had widely ignored. Interestingly, stress-response hormesis for algal growth was observed Chlorella vulgaris as a single-celled model organism. Few physiological parameters, such density, plasmolysis, levels reactive oxygen species, exhibited facile recovery. In contrast, effects on chlorophyll levels,...
Due to the numerous factors (e.g., nanoparticle [NP] properties and experimental conditions) influencing nanotoxicity, it is difficult identify priority dominating nanotoxicity. Herein, by integrating data from literature a random forest model, determining reproductive toxicity were successfully screened highly heterogeneous data. Among 10 more than 18 different NPs, NP type exposure pathway found dominantly determine accumulation. The of various NPs primarily depended on indicators....
Background and Aims: Metabolism in the liver is dysregulated obesity, contributing to various health problems including steatosis insulin resistance. While pathogenesis of lipid accumulation has been extensively studied, protective mechanism against challenge remains unclear. Here, we report that Src homology 3 domain binding kinase 1 (SBK1) a regulator hepatic metabolism systemic sensitivity response obesity. Approach Results: Enhanced Sbk1 expression was found high‐fat diet (HFD)–induced...
Crop plants are intimately associated with an enormous diversity of microbiota that profoundly influence their productivity, but the contribution plant-microbiome interactions to grain yield and quality sorghum during different developmental stages remains unclear. The aim this study was evaluate relative importance sorghum-associated bacterial fungal communities in compartments predicting quality. We collected soil plant samples from various vegetative (jointing heading stages) reproductive...
Epilepsy is a common neurologic disorder. While good clinical solution still missing, studies have confirmed that exosomes (Exos) derived from adipose-derived stem cells (ADSCs) had therapeutic effect on various diseases, including neurological diseases. Therefore, this study aimed to reveal whether ADSC-Exo treatment could improve kainic acid (KA)-induced seizures in epileptic mice. ADSCs and Exos were isolated. Mice generated with KA-induced seizures. ELISA was used detect inflammatory...
Abstract Currently, nanomaterials face a dilemma due to their advantageous properties and potential risks human health. Here, strategy improve both nanomaterial biocompatibility functionality is established by screening small metabolites from cells as coatings. A metabolomics analysis of exposed nanosilver (nAg) integrates volcano plots ( t ‐tests fold change analysis), partial least squares‐discriminant (PLS‐DA), significance microarrays (SAM) identifies six l ‐aspartic acid, ‐malic...
Abstract Aedes albopictus is the vector of arbovirus diseases including yellow fever, dengue, Zika virus, and chikungunya it poses an enormous threat to human health worldwide. Previous studies have revealed that haedoxan A (HA), which insecticidal sesquilignan from Phryma leptostachya L., a highly effective natural insecticide for managing mosquitoes houseflies; however, mechanisms underlying response Ae. after treatment with sublethal concentrations HA not clear. Here, high-throughput...
Macrophage polarization affects the progression of pathogenic bacterial infections. Lactobacillus is widely used to interact with macrophages and exert specific immunomodulatory activities. In this study, we investigated regulation macrophage against Salmonella enterica serotype Typhimurium (STM) by plantarum JL01 (LP), explore prevention treatment strategies for salmonellosis. We assessed in vitro differential RAW 264.7 mouse bone marrow (BMMs) LP STM, measuring protein cytokine levels,...
Abstract Introduction Protists are unicellular eukaryotes including important predators, parasites and phototrophs, play pivotal roles in organic matter decomposition, biogeochemical nutrient cycling various ecosystem functions. Unravelling the impact of climate warming on soil protists is paramount predicting how these microorganisms will continue to provide essential services face changing climatic conditions. Materials Methods We examined effects 5‐year simulated scenario, with...
This work presents a 2-step systematic modeling process for the electromagnetic and thermal analysis of washing machine during full wash cycle. The motor is single-phase capacitor-run induction motor. Using combination 2D software 1D system simulation tool, designer able to evaluate power losses heat rise, at limited cost in time resources.
Periplocoside P (PSP) is a major component of Periploca sepium Bunge known for its potent insecticidal activity. V-Type adenosine triphosphatase (V-ATPase), which widely distributed in the cytoplasmic membranes and organelles eukaryotic cells, plays crucial role synaptic excitability conduction. Previous research has shown that PSP targets apical membrane goblet cells insect midgut. However, effects on transmission at neuromuscular junction are often overlooked.The bioassay revealed...