- RNA and protein synthesis mechanisms
- CRISPR and Genetic Engineering
- Bacteriophages and microbial interactions
- Enzyme Production and Characterization
- Flow Measurement and Analysis
- Endoplasmic Reticulum Stress and Disease
- RNA modifications and cancer
- Amino Acid Enzymes and Metabolism
- Drug Transport and Resistance Mechanisms
- Non-Invasive Vital Sign Monitoring
- Enzyme Structure and Function
- Indoor and Outdoor Localization Technologies
- Bacterial Genetics and Biotechnology
- Malaria Research and Control
Shanghai Jiao Tong University
2022-2025
Zhengzhou University of Light Industry
2018
Ribonuclease P (RNase P) plays a vital role in the maturation of tRNA across bacteria, archaea, and eukaryotes. However, how RNase assembles various components to achieve specific cleavage precursor (pre-tRNA) different organisms remains elusive. In this study, we employed single-molecule fluorescence resonance energy transfer probe dynamics from E. coli ( Escherichia ) Mja Methanocaldococcus jannaschii during pre-tRNA by incorporating five Cy3-Cy5 pairs into P. Our results revealed...
Low visibility and hot smoke environment under fire conditions can largely hamper the related rescue processes. Ultrasound obstacle avoidance technology is then useful for guidance. However, biggest challenge of adopting ultrasound comes from accurate distance measurements disturbances high temperature soot particle concentration. It critical to measure propagation speed complicated conditions. Therefore, in this study, a baffle calibration method was proposed improve accuracy measurement an...
Gametogenesis is an essential step for malaria parasite transmission and activated in mosquito by signals including temperature drop, pH change, mosquito-derived xanthurenic acid (XA). Recently, a membrane protein gametogenesis 1 (GEP1) was found to be responsible sensing these interacting with giant guanylate cyclase α (GCα) activate the cGMP-PKG-Ca2+ signaling pathway gametogenesis. However, molecular mechanisms this process remain unclear. In study, we used AlphaFold2 predict structure of...