Morgan J. Rothschadl

ORCID: 0009-0009-7996-7671
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About
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Research Areas
  • Pluripotent Stem Cells Research
  • Erythropoietin and Anemia Treatment
  • PI3K/AKT/mTOR signaling in cancer
  • PARP inhibition in cancer therapy

University of South Dakota
2022-2023

Trophic factors are secreted proteins that can modulate neuronal integrity, structure, and function. Previous preclinical studies have shown synergistic effects on decreasing apoptosis improving behavioral performance after stroke when combining two such trophic factors, erythropoietin (EPO) insulin-like growth factor-1 (IGF-1). However, EPO elevate the hematocrit level, which be life-threatening for non-anemic individuals. A chemically engineered derivative of EPO, carbamoylated (CEPO),...

10.3390/life13091826 article EN cc-by Life 2023-08-29
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