A5101908193- Cloud Computing and Resource Management
- Bayesian Modeling and Causal Inference
- Signaling Pathways in Disease
- Bone Tissue Engineering Materials
- interferon and immune responses
- Fibroblast Growth Factor Research
- Distributed systems and fault tolerance
- Computational Geometry and Mesh Generation
- Cardiac Fibrosis and Remodeling
- Software-Defined Networks and 5G
- Cardiac Ischemia and Reperfusion
- Access Control and Trust
- Robotics and Sensor-Based Localization
- Web Data Mining and Analysis
- MXene and MAX Phase Materials
- Software System Performance and Reliability
- Immune Response and Inflammation
- Robotic Path Planning Algorithms
- Anomaly Detection Techniques and Applications
- Network Security and Intrusion Detection
- Inflammasome and immune disorders
- Nanoplatforms for cancer theranostics
Nankai University
2024
Shanghai Changzheng Hospital
2018-2023
Tsinghua University
2019
Background Stimulation of IFN genes (STING) is central to the production interferon and proinflammatory cytokines in response microbial DNA or self-DNA cytosol. The detrimental role activation STING during sepsis has been well documented. Methods Here, we found that gelsevirine (GS) potently inhibit inflammatory cytokine induction macrophages exposed agonists (2'3'-cGAMP, stimulatory (ISD), poly(dA:dT)). I n silico docking analysis surface plasmon resonance binding study showed GS bonds with...
Incurable implant-related infection may cause catastrophic consequences due to the existence of a biofilm that resists infiltration host immune cells and antibiotics. Innovative approaches inspired by nanomedicine, e.g., engineering innovative multifunctional bionic coating systems on surface implants, are becoming increasingly attractive. Herein, 2D black phosphorus nanosheets (BPs) were loaded onto hydroxyapatite (HA)-coated metal implant construct BPs@HA composite coating. With its...
The availability of microservice systems is critical to business operations and corporate reputation. However, the dynamics complexity introduce significant challenges performance issue diagnosis large-scale systems. After investigating hundreds real-world cases in Tencent, we find that previous troubleshooting approaches fail accurately localize root causes because they overlook inconsistency between causality calling relationships. Therefore, propose a novel approach, MicroDig, diagnose...
Collision detection has attracted attention of researchers for decades in the field computer graphics, robot motion planning, aided design, etc. A large number successful algorithms have been proposed and applied, which make use convex polytopes bounding volumes as primitives. However, those shapes rely significantly on complexity meshes. This paper deals with collision simple exact mathematical descriptions, such ellipsoids superquadrics. These primitives a wide range applications...
Shared autonomy functions as a flexible framework that empowers robots to operate across spectrum of levels, allowing for efficient task execution with minimal human oversight. However, humans might be intimidated by the autonomous decision-making capabilities due perceived risks and lack trust. This paper proposed trust-preserved shared strategy allows seamlessly adjust their level, striving optimize team performance enhance acceptance among collaborators. By enhancing relational event...
Background Fibroblast growth factor(FGF)10 is a member of the FGF family, mainly expressed in epithelial cells and mesenchymal cells, fibroblasts adult liver, lungs, brain, intestines other organs. It plays diverse roles different organs tissues, such as angiogenesis, promoting wound healing, participating process embryo development. Objective This review will lay good foundation for further study on physiological function mechanism role FGF10. Content This paper reviews recent...