A5089982818- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiovascular and exercise physiology
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Hemodynamic Monitoring and Therapy
- Diabetes Treatment and Management
- Nutrition and Health in Aging
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Case Reports on Hematomas
- Hormonal Regulation and Hypertension
- Frailty in Older Adults
- Optical Imaging and Spectroscopy Techniques
- Cardiac Valve Diseases and Treatments
- Concrete Corrosion and Durability
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Bartonella species infections research
- Takotsubo Cardiomyopathy and Associated Phenomena
- Pulmonary Hypertension Research and Treatments
- Herpesvirus Infections and Treatments
- Innovative concrete reinforcement materials
- Cytomegalovirus and herpesvirus research
- Cardiovascular and Diving-Related Complications
- Pharmaceutical Practices and Patient Outcomes
Gunma University
2023-2025
National Defense Medical College
2023-2025
National Institute of Technology, Toyota College
2023
Ashikaga Red Cross Hospital
2022
Abstract Aims Left ventricular (LV) diastolic dysfunction and heart failure with preserved ejection fraction (HFpEF) are common cardiac complications of patients systemic sclerosis (SSc). Exercise stress echocardiography is often used in symptomatic SSc to detect abnormal increases pulmonary pressures during exercise, but the pathophysiologic prognostic significance exercise assess presence HFpEF these unclear. Methods results Patients (n=140) underwent ergometry simultaneous expired gas...
Abstract Aims Exercise stress echocardiography (ESE) is often used to identify heart failure with preserved ejection fraction (HFpEF) in patients presenting dyspnea. However, diagnostic criteria have not been standardized. Here, we sought develop ESE-based diagnose HFpEF dyspneic patients. Methods and Results A total of 81 consecutive dyspnea who underwent exercise right catheterization ESE were evaluated. Diagnosis was ascertained by directly-measured hemodynamics (61 20 controls). Logistic...
Left atrial (LA) dysfunction is common in heart failure (HF) with preserved ejection fraction. However, data on the pathophysiologic impacts of impaired LA functional reserve remained limited. We sought to determine association abnormal dynamics during exercise cardiovascular reserve, capacity, and clinical outcomes.
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is a syndrome characterized by multiple cardiac reserve limitations during exercise. Cardiac power output (CPO) an index of global performance and can be estimated non-invasively echocardiography. We hypothesized that CPO exercise would associated impaired cardiovascular reserve, intolerance, adverse outcomes in HFpEF. Methods results Exercise stress echocardiography was performed 425 dyspnoeic patients [217 HFpEF 208...
Sodium-glucose cotransporter-2 inhibitors (SGLT-2is) show cardiovascular protective effects, regardless of the patient’s history diabetes mellitus (DM). SGLT2is suppressed adverse events in patients with type 2 DM, and furthermore, SGLT-2is reduced risk worsening heart failure (HF) or death HF. Along these research findings, are recommended for HF latest guidelines. Despite benefits, concern surrounding increasing body weight loss other has not yet been resolved, especially sarcopenia...
Extracardiac comorbidities are highly prevalent in patients with heart failure preserved ejection fraction (HFpEF). We investigated the pathophysiological contribution of an extracardiac comorbidity burden to cardiac function, exercise capacity, and prognosis HFpEF. A total 775 (372 HFpEF 403 control subjects) underwent echocardiography, simultaneous expired gas analysis. separated previously validated Meta-Analysis Global Group Chronic Heart Failure (MAGGIC) risk score into cardiac,...
Coronary artery spasm (CAS) is an underrecognized cause of heart failure, even in the absence obstructive coronary disease. We report three cases failure which CAS was identified as critical etiology. All patients exhibited symptoms with nonobstructive arteries, and provocation testing confirmed epicardial spasm. In two cases, cardiac magnetic resonance imaging revealed ischemic patterns consistent CAS-related injuries. Calcium channel blockers effectively stabilize signs related to failure....
Anemia is common in patients with heart failure preserved ejection fraction (HFpEF) and associated exercise intolerance. However, there are limited data on how anemia contributes to reduced capacity HFpEF. We aimed characterize capacity, cardiovascular ventilatory reserve, the oxygen (O2) pathway anemic HFpEF.A total of 238 HFpEF 248 dyspneic without HF underwent ergometry stress echocardiography simultaneous expired gas analysis. Patients were classified into two groups based presence...
Venous thromboembolism (VTE) is a common comorbidity of cancer, often referred to as cancer-associated thrombosis (CAT). Even though its prevalence has been increasing, clinical picture not thoroughly investigated. In this single-center retrospective observational study, 259 patients who were treated for pulmonary embolism (PE) between January 2015 and December 2020 available analysis. The divided by the presence or absence concomitant malignancy, those with malignancy (N = 120, 46%) further...
Hospitalization with a first episode of heart failure (HF) is serious event associated poor clinical outcomes in HF preserved ejection fraction (HFpEF). Identification HFpEF via detection elevated left ventricular filling pressure at rest or during exercise may allow early intervention. Benefits treatment mineralocorticoid receptor antagonists (MRAs) established have been reported, but use MRAs not well studied without prior hospitalization.We retrospectively 197 patients who did...
Background: Recent evidence suggests the efficacy and safety of sodium-glucose transporter 2 inhibitors (SGLT-2is) in heart failure (HF) patients. However, there still remain concerns their use among patients with physical or cognitive frailty. Methods: West Tokyo Heart Failure (WET-HF) Registry is an ongoing prospective multicenter registry Japan enrolling all who were hospitalized for acute decompensated failure. We retrospectively analyzed impact frailty-related factors (FF) on...
We aimed to diagnose arteriosclerosis by identifying the fluorescence that originates from substance in arterial wall of arteriosclerotic vessels. The inner surface abdominal aorta rabbit models was illuminated an excitation light and multispectral images were obtained. spectra sites shown be different those normal sites. then calculated a ratio intensity at wavelength two significant differences for each pixel, reconstructed images. As result, we succeeded ‘disease mapping’, which can...