A5101379100- Advanced Biosensing Techniques and Applications
- Head and Neck Surgical Oncology
- Transportation Planning and Optimization
- Adenosine and Purinergic Signaling
- Animal Virus Infections Studies
- Wheat and Barley Genetics and Pathology
- Gynecological conditions and treatments
- Gold and Silver Nanoparticles Synthesis and Applications
- Drilling and Well Engineering
- Concrete and Cement Materials Research
- Liver physiology and pathology
- Ovarian function and disorders
- Reproductive System and Pregnancy
- Sperm and Testicular Function
- RNA modifications and cancer
- Nanocluster Synthesis and Applications
- interferon and immune responses
- Maternal and Perinatal Health Interventions
- Advanced ceramic materials synthesis
- Rice Cultivation and Yield Improvement
- Mesenchymal stem cell research
- Immune cells in cancer
- Autophagy in Disease and Therapy
- Hematopoietic Stem Cell Transplantation
- Hepatitis C virus research
Second Affiliated Hospital of Guangzhou Medical University
2024-2025
Southern Medical University
2025
State Key Laboratory of Respiratory Disease
2024-2025
Guangzhou Medical University
2024-2025
National Clinical Research Center for Digestive Diseases
2024
Sichuan University
2024
West China Second University Hospital of Sichuan University
2024
Peking University
2024
Institute of Hematology & Blood Diseases Hospital
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
S-Palmitoylation is a reversible post-translational modification involving saturated fatty acid palmitate-to-cysteine linkage in the protein, which guides many aspects of macrophage physiology health and disease. However, precise role underlying mechanisms palmitoylation Mycobacterium tuberculosis infection macrophages remain elusive. Here, we found that M. induced expression zinc-finger DHHC domain-type palmitoyl-transferases (ZDHHCs), particularly ZDHHC2, mouse macrophages. Furthermore,...
Abstract Autoreactive CD4 + T helper cells are critical players that orchestrate the immune response both in multiple sclerosis (MS) and other neuroinflammatory autoimmune diseases. Ubiquitination is a posttranslational protein modification involved regulating variety of cellular processes, including cell differentiation function. However, only limited number E3 ubiquitin ligases have been characterized terms their biological functions, particularly In this study, we found RING finger 213...
As one of the most rapidly evolving proteins genus Betacoronavirus, open reading frames (ORF8's) function and potential pathological consequence in vivo are still obscure. In this study, we show that secretion ORF8 is dependent on its N-terminal signal peptide sequence can be inhibited by reactive oxygen species scavenger endoplasmic reticulum-Golgi transportation inhibitor cultured cells. To trace effect possible secretion, examined plasma samples coronavirus disease 2019 (COVID-19)...
Macrophages are considered to play an important role in the development of chronic apical periodontitis (CAP). However function tissue resident macrophages CAP is unclear. This study aims investigate potential different origins CAP. Chemokine receptor-2 deficiency (CCR2-/-) mice and C57BL/6N (control group, WT mice) were used induce periodontitis. The pulp mandibular first molars both sides exposed oral environment. After 0, 7, 21, 28 days explosion, animals sacrificed, bones collected...
Cement clinker with low CO 2 emission was prepared in laboratory, which mainly consist of belite (C S), calcium sulfoaluminate 4 A 3 and ferrite AF). The mineral composition optimized for better compressive strength development. chemical physical properties this cement were characterized through X-ray diffraction (XRD), back scattered electron-scanning electron microscopy (BSE-SEM) differential thermal analysis (DTA). results reveal that C S governs most the at early ages, while contributes...
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the standard and curative treatment strategy for patients with hematologic malignancies. Recently, decitabine-included regimens have been investigated by several studies including ours, which may prevent relapse of primary malignant diseases.This study was to retrospectively evaluate a 7-day regimen reduced dose idarubicin malignancies who underwent allo-HSCT.A total 84 were enrolled, 24 cases in 60 5-day decitabine groups,...
As the construction of China's transportation infrastructure pushes forward in a fast pace, comprehensive passenger hub will become an important node for urban network. This paper analyzes necessity constructing travel information sharing platform against background traffic informatization. Based on analysis demand, system function is designed, alongside with orientation and structure. Then it proposes logical structure platform, whole process realization detail, including collecting,...
Different countries have developed high-speed rail system in different ways. The unique circumstances China led to the need figure out which is best operating mode of passenger flow between and conventional rail, how integrate operations into network. This paper provides a brief description three operation patterns convention rail. Based on this description, generalized cost model modes are compared has been order estimate optimal coverage trains. takes account some parameters such as train...
1985年由抑食金球藻(Aureococcus anophagefferens)引发的褐潮首次出现于美国东北部的一些沿海海湾,后来又于1997年在南非的萨尔达尼亚湾暴发;2009年秦皇岛海域褐潮的暴发使中国成为世界上第三个受其影响的国家。尽管抑食金球藻对人体健康没有直接的不利影响,但是它会导致贝类生长缓慢甚至死亡,从而造成巨大的经济损失和严重的生态问题。本文对国内外学者近年来在抑食金球藻的生理生化特征、暴发与消亡的原因、生态危害及预防措施等方面的研究进行了系统总结,为抑食金球藻褐潮防治及维持海洋生态系统的稳定提供科学依据。