A5078435032- Neuroscience and Neuropharmacology Research
- Tryptophan and brain disorders
- Ginseng Biological Effects and Applications
- Eicosanoids and Hypertension Pharmacology
- Sulfur Compounds in Biology
- Genomics, phytochemicals, and oxidative stress
- Medicinal Plant Pharmacodynamics Research
- Biochemical effects in animals
- Heart Rate Variability and Autonomic Control
- Neurotransmitter Receptor Influence on Behavior
- Pain Management and Treatment
- Receptor Mechanisms and Signaling
- Neuroscience of respiration and sleep
- Nitric Oxide and Endothelin Effects
Harbin Medical University
2011-2024
Third Affiliated Hospital of Harbin Medical University
2011-2024
Heilongjiang Academy of Sciences
2017
In the present study, potent inducers of phase II detoxifying and antioxidant stress responsive to icariside was investigated. First, a dose 0-10 µM showed no significantly cytotoxicity on HepG2 cells by MTT assays could enhance cellular GSH levels ELISA assay. Then, potential roles ERK, Akt JNK in regulation II-induced Nrf2-dependent ARE transcriptional activity as well ARE-mediated endogenous HO-1 glutathione GST protein expression were estimated. Icariside activated nuclear translocation...
Propofol (2, 6-diisopropylphenol), is an anesthetic and routinely used for the humans sedation during surgery.The potent inducers of phase II detoxifying antioxidant stress responsive to propofol were investigated.First, a dose 25-100 µM showed no significant cytotoxicity on SH-SY5Y cells pre-treatment with (25-100 μM) 8h prevented cell death maintained integrity following exposure 1 mM hydrogen peroxide by MTT assays.Then, increase in generation ROS treatment was significantly attenuated 8...
<h3>Background and Objectives</h3> To determine whether stellate ganglion block (SGB) treatment exerts protective effects against isoproterenol (ISO)–induced acute myocardial ischemia (AMI) due to its antioxidant effects, we aimed evaluate the of different lateral SGB agents on tissue status in ISO-induced AMI male Sprague-Dawley rats. <h3>Methods</h3> The model received an ISO overdose make cardiac damage at a single dose 110 mg/kg injected subcutaneously into rats groups 15 minutes after...
Narcotic drugs refer to that have anesthetic effects on the central nervous system, and they easily produce physical dependence mental can be addictive due continuous use, abuse or unreasonable use. In this paper, bioinformatics data analysis mining techniques were used analyze methylation differences in transcriptional clinical of narcotic addiction public databases, explore mechanism addiction, mine some norepinephrine drugs. This study confirmed possibility using as an auxiliary drug for...