A5068535758- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Cardiovascular and Diving-Related Complications
- Cardiac tumors and thrombi
- Venous Thromboembolism Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Pericarditis and Cardiac Tamponade
- Intracranial Aneurysms: Treatment and Complications
- Pulmonary Hypertension Research and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiomyopathy and Myosin Studies
- Acute Ischemic Stroke Management
- Orthopaedic implants and arthroplasty
- Cardiovascular Health and Disease Prevention
- Cardiovascular Disease and Adiposity
- Coronary Interventions and Diagnostics
- Spinal Fractures and Fixation Techniques
- Cardiovascular Issues in Pregnancy
Toho University
2013-2024
Minneapolis Heart Institute Foundation
2019-2024
Toho University Ohashi Medical Center
2013-2024
National Kyushu Medical Center
2020-2023
Clinical Research Institute
2023
Abbott Northwestern Hospital
2019-2022
Valve (United States)
2020-2022
St. Mary's Hospital
2021
St Mary's Hospital
2021
Kurume University
2021
Although transcatheter aortic valve replacement (TAVR) therapy continues to grow, there have been concerns about the occurrence of hypoattenuating leaflet thickening (HALT), which may affect prosthesis function or durability. This study aimed examine frame factors and correlate their extent frequency HALT clinical outcomes.We prospectively examined 565 patients with cardiac computed tomography screening for at 30 days after balloon-expandable SAPIEN3 self-expanding EVOLUT TAVR. Deformation...
The three major immunocompetent cells in human peripheral blood (lymphocytes, neutrophils, and monocytes) were shown to be effector for antibody-dependent cell-mediated cytotoxicity (ADCC) against influenza virus-infected baby hamster kidney vitro. Lymphocyte was mediated by FcIgG receptor-bearing null Ty cells. These populations best defined HNK-1, a monoclonal antibody natural killer ADCC-mediator Antibody responsible ADCC detectable sera of young children after infection vaccination with...
Background: Hypoattenuated leaflet thickening (HALT), identified on functional cardiac computed tomography (CTA), can affect valve function and clinical outcomes. The objective of this study was to assess the impact HALT outcomes in patients treated with transcatheter aortic replacement (TAVR). Methods: In July 2015, Minneapolis Heart Institute implemented prospective screening at 30-day post-TAVR CTA. Patients evidence were recommended initiate anticoagulation for 3 6 months warfarin....
BACKGROUND: The optimal duration of anticoagulation therapy for isolated distal deep vein thrombosis in patients with cancer is clinically relevant, but the evidence lacking. prolonged could have a potential benefit prevention thrombotic events; however, it also increase risk bleeding. METHODS: In multicenter, open-label, adjudicator-blinded, randomized clinical trial at 60 institutions Japan, we randomly assigned thrombosis, 1-to-1 ratio, to receive either 12-month or 3-month edoxaban...
<h3>Importance</h3> Chronic aortic regurgitation (AR) causes left ventricular (LV) volume overload, which results in progressive LV remodeling negatively affecting outcomes. Whether cardiac magnetic resonance (CMR) volumetric quantification can provide incremental risk stratification over standard clinical and echocardiographic evaluation patients with chronic moderate or severe AR is unknown. <h3>Objective</h3> To compare measurements by CMR echocardiography between without heart failure...
Abstract Background The natural history of patients with moderate aortic stenosis (AS) is poorly understood. We aimed to determine the long-term outcomes AS. Methods examined AS defined by echocardiography in our healthcare system, and performed survival analyses for occurrence death, heart failure (HF) hospitalization, progression AS, accounting symptoms, left ventricular dysfunction, comorbidities. Results 729 (median age, 76 years; 59.9 % men) a median follow-up 5.0 years (interquartile...
A 29-year-old woman who worked as a KAATSU (a type of body exercise that involves blood flow restriction) instructor visited our emergency room with chief complaint swelling and left upper limb pain. Chest computed tomography (CT) showed non-uniform contrast images corresponding to the site from axillary vein subclavian vein; vascular ultrasonography revealed thrombotic obstruction at same site, leading diagnosis Paget-Schroetter syndrome (PSS). We herein report experience case PSS derived...
A 69-year-old man was admitted to our hospital under diagnosis of pneumonia due severe acute respiratory syndrome-corona virus 2 (SARS-CoV-2) (Day 0). He underwent endotracheal intubation from Day 3. Although his condition improved and anesthetic drugs were discontinued, no cough reflex observed despite having been performed until 17. His tendon reflexes also diminished. We suspected that he had developed Guillain-Barré syndrome (GBS), administered intravenous immunoglobulin 18. The absence...
Transcatheter aortic valve replacement (TAVR) procedural planning requires computed tomography angiography (CTA) which allows for the assessment of left ventricular global longitudinal strain (CTA-LVGLS). There is, however, limited data on feasibility CTA-LVGLS, and its prognostic value. This study sought to evaluate incremental value baseline change in CTA-LVGLS after TAVR, their association with post-TAVR outcomes.A total 431 patients who underwent multiphasic gated CTA using dual-source...
Background: Although transcatheter edge-to-edge repair (TEER) is effective and safe, there a need for better prediction of optimal outcomes. We aimed to determine predictors reduction in mitral regurgitation (MR) survival with TEER. Methods: examined anatomy its change TEER on outcomes 183 patients (age, 82 [77–87] years; 53% women). Coaptation reserve was measured as the distance continuous apposition A2 P2 leaflet segments 2-dimensional apical long-axis imaging at site predominant jet MR....
A 70-years-old male with a history of hypertension and drug resistant paroxysmal atrial fibrillation (AF) presented to our hospital for catheter ablation his symptomatic AF. He had no prior surgical or percutaneous procedure close exclude the left appendage (LAA). transesophageal echocardiography (TEE) was performed rule out intra-cardiac thrombus procedure. Although TEE imaging at multiple acquisition angles obtained, LAA could not be visualized an absence suspected. An confirmed using...
<b><i>Background:</i></b> To validate the hypothesis that cryptogenic stroke with multiple infarcts included embolic due to left atrial appendage (LAA) dysfunction, present retrospective observational study was aimed clarify association between LAA flow velocity (LAA-FV) and in patients stroke. <b><i>Methods:</i></b> From consecutive admitted our hospital within 7 days after onset, without brain magnetic resonance imaging (MRI) on admission or...
In patients with left ventricular hypertrophy (LVH), LV midwall fractional shortening (FS) is used as a measure of systolic performance that more physiologically appropriate than conventional FS. For evaluation volume and ejection fraction (EF), 2-dimensional (2D) echocardiography accurate M-mode echocardiography. The purpose this study was to assess by EF using 2D speckle tracking (STE). Sixty were enrolled in the study. Patients divided into two groups LVH (n = 30) without (control group,...
Bioprosthetic valve fracture (BVF) during valve-in-valve TAVR (transcatheter aortic replacement) is a procedural adjunct designed to optimize the expansion of transcatheter heart and reduce patient-prosthesis mismatch by using high-pressure balloon intentionally surgical (SHV).
Objectives: Cilostazol, a type III phosphodiesterase inhibitor, is an antiplatelet agent with vasodilating properties. Positive inotropic and chronotropic effects are frequently observed cilostazol, but there few reports on the influence of cilostazol left ventricular function. The aim this study was to assess effect using tissue Doppler imaging (TDI) two-dimensional speckle-tracking echocardiography (2D-STE). Methods: Thirty-five patients normal ejection fraction were enrolled in study....
Abstract Genetic Creutzfeldt–Jakob disease (gCJD) with V180I prion protein gene ( PRNP ) mutation shows weaker (PrP) deposition histologically compared sporadic CJD, and it is more difficult to detect protease‐resistant in immunoblotting. However, we previously reported the autopsy case of a patient gCJD who was treated pentosan polysulfate sodium (PPS); this had increased PrP deposition. It has been suggested that PPS might reduce PrP; however, detailed pharmacological histopathological...