A5059617617- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Coronary Interventions and Diagnostics
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiovascular Effects of Exercise
- Cardiac pacing and defibrillation studies
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 and healthcare impacts
- Venous Thromboembolism Diagnosis and Management
- Cardiac Health and Mental Health
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Takotsubo Cardiomyopathy and Associated Phenomena
- Lipoproteins and Cardiovascular Health
- Cardiovascular Disease and Adiposity
- Cardiac electrophysiology and arrhythmias
Minneapolis Heart Institute Foundation
2016-2025
Abbott Northwestern Hospital
2015-2025
Prairie Vascular Institute
2024
Christ Hospital
2022
Allina Health
2018-2022
Christ Hospital
2020-2022
Valve (United States)
2017-2021
Hennepin Healthcare Research Institute
2021
Bethel University
2020
Cedars-Sinai Medical Center
2014-2019
Sudden deaths in young competitive athletes are tragic events, with high public visibility. The importance of race and gender respect to sport the diagnosis causes sudden death has generated substantial interest.The US National Registry Death Athletes, 1980-2011, was accessed define epidemiology athletes. A total 2406 were identified aged 19 ± 6 years engaged 29 diverse sports.Among 842 autopsy-confirmed cardiovascular diagnoses, incidence males exceeded that females by 6.5-fold (1:121; 691...
Background— Hypertrophic cardiomyopathy (HCM) is prominently associated with risk for sudden death and disease progression, largely in young patients. Whether patients of more advanced age harbor similar risks unresolved, often creating clinical dilemmas, particularly decisions primary prevention implantable defibrillators. Methods Results— We studied 428 consecutive HCM presenting at ≥60 years followed 5.8±4.8 years; 53% were women. Of the patients, 279 (65%) survived to 73±7 (range, 61–96...
An increasing number of patients with severe coronary artery disease (CAD) are not candidates for traditional revascularization and experience angina in spite excellent medical therapy. Despite limited data regarding the natural history predictors adverse outcome, these have been considered at high risk early mortality. The OPtions In Myocardial Ischemic Syndrome Therapy (OPTIMIST) program Minneapolis Heart Institute offers investigational therapies refractory angina. A prospective clinical...
Background— Youthful age has been considered the time of greatest risk for patients with hypertrophic cardiomyopathy (HCM), largely because possibility sudden death. The last 2 decades have witnessed more reliable identification at-risk and utilization implantable cardioverter-defibrillators prevention death, other contemporary treatment options. Whether such management advances significantly altered considerable mortality rate young HCM remains unresolved. Methods Results— We studied...
Regional ST-segment-elevation myocardial infarction systems are being developed to improve timely access primary percutaneous coronary intervention (PCI). System delays may diminish the mortality benefit achieved with PCI in patients, but specific reasons for and clinical impact of patients transferred unknown.This was a prospective, observational study 2034 at single center as part regional system from March 2003 December 2009. Despite long-distance transfers, 30.4% (n=613) were treated ≤...
Systemic anticoagulation is a standard of care in adult patients supported by extracorporeal membrane oxygenation (ECMO) to prevent circuit thrombosis and subsequent thromboembolic events. Unfractionated heparin has long been considered the anticoagulant choice, but emerging evidence reports successful ECMO runs with direct thrombin inhibitors. This retrospective study sought determine whether bivalirudin offers distinct clinical benefits as choice ECMO. Primary end points included...
To evaluate the impact of COVID-19 pandemic migitation measures on ST-elevation myocardial infarction (STEMI) care.We previously reported a 38% decline in cardiac catheterization activations during early phase mitigation measures. This study extends our observations using larger sample STEMI programs representative different US regions with inclusion more contemporary data.Data from 18 hospitals or healthcare systems January 2019 to April 2020 were collecting including number for STEMI,...
Background: Hypoattenuated leaflet thickening (HALT), identified on functional cardiac computed tomography (CTA), can affect valve function and clinical outcomes. The objective of this study was to assess the impact HALT outcomes in patients treated with transcatheter aortic replacement (TAVR). Methods: In July 2015, Minneapolis Heart Institute implemented prospective screening at 30-day post-TAVR CTA. Patients evidence were recommended initiate anticoagulation for 3 6 months warfarin....
ABSTRACT Background Sex differences in ST‐segment elevation myocardial infarction (STEMI) due to obstructive coronary artery disease (CAD) are well‐established, but limited research exists on sex STEMI patients with nonobstructive arteries (MINOCA) and MINOCA mimickers. Methods We analyzed 8560 consecutive patients, enrolled the Midwest Consortium from 2003 2020. Patients non‐obstructive CAD were classified into (defined as < 50% stenosis confirmed or suspected plaque disruption,...
To determine the safety and efficacy of a pharmaco-invasive reperfusion strategy utilizing half-dose fibrinolysis combined with transfer for immediate percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) patients presenting to remote rural hospitals. Primary PCI is preferred STEMI if performed timely manner. However, <20% transferred USA have door-to-balloon times <2 h.Prospective data from Level 1 MI programme were analysed. All Minneapolis Heart Institute...
Background: Reports of race-related triathlon fatalities have raised questions regarding athlete safety. Objective: To describe death and cardiac arrest among participants. Design: Case series. Setting: United States. Participants: Participants in U.S. races from 1985 to 2016. Measurements: Data on deaths arrests were assembled such sources as the National Registry Sudden Death Athletes (which uses news media, Internet searches, LexisNexis archival databases, clipping services) USA Triathlon...