A5040042710- Acute Myocardial Infarction Research
- Cardiac Arrest and Resuscitation
- Coronary Interventions and Diagnostics
- COVID-19 and healthcare impacts
- Mechanical Circulatory Support Devices
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- COVID-19 Clinical Research Studies
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- Cardiac electrophysiology and arrhythmias
- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Arrhythmias and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Emergency and Acute Care Studies
- Cardiac and Coronary Surgery Techniques
- Vascular Procedures and Complications
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Lipoproteins and Cardiovascular Health
- ECG Monitoring and Analysis
- Cardiac Fibrosis and Remodeling
University of Saskatchewan
2018-2025
Royal University Hospital
2018-2024
Saskatoon Medical Imaging
2020-2024
Saskatchewan Health
2022-2023
Clinical Research Institute
2017-2022
Canadian VIGOUR Centre
2013-2021
University of Alberta
2013-2021
Shore Memorial Hospital
2021
University of Regina
2021
Duke University
2017-2019
Background: Regional variations in reperfusion times and mortality patients with ST-segment–elevation myocardial infarction are influenced by differences coordinating care between emergency medical services (EMS) hospitals. Building on the Accelerator-1 Project, we hypothesized that time to could be further reduced enhanced regional efforts. Methods: Between April 2015 March 2017, worked 12 metropolitan regions across United States 132 percutaneous coronary intervention–capable hospitals 946...
Introduction: Scant data exist on the epidemiology and clinical characteristics of atrial fibrillation in Kenya.Traditionally, (AF) sub-Saharan Africa is as a result rheumatic valve disease.However, with economic transition Africa, risk factors associated complications this arrhythmia are likely to change.Methods: A retrospective observational survey was carried out between January 2008 December 2010.Patients discharge diagnosis either or flutter were included for analysis.The...
Abstract Background Most people do not recognize symptoms of neurological and cardiac emergencies in a timely manner. This leads to delays hospital arrival reduced access therapies that can open arteries. We created smartphone app help patients families evaluate if may be high risk for stroke or heart attack (myocardial infarction, MI). The ECHAS (Emergency Call Heart Attack Stroke) guides users assess their through evidence-based questions test weakness one arm by evaluating finger-tapping...
Processing liquid chromatography–mass spectrometry-based metabolomics data using computational programs often introduces additional quantitative uncertainty, termed variation in a previous work. This work develops solution to automatically recognize metabolic features with set. tool, AVIR (short for "Accurate eValuation of alIgnment and integRation"), is support vector machine-based machine learning strategy (https://github.com/HuanLab/AVIR). The rationale that have poor correlation between...
The contemporary role of prophylactic anticoagulation following extensive anterior wall ST-segment myocardial infarction (STEMI) is unclear.We evaluated STEMI patients with left ventricle dysfunction (left ventricular ejection fraction ≤40%) ("high risk"), categorized by warfarin use, within a regional STEMI. Patients pre-existing atrial fibrillation were excluded. primary outcome was an adjusted (for Global Registry Acute Coronary Events risk score) 1-year composite recurrent ischemia,...
The benefit of β-blocker use beyond 3 years after a myocardial infarction (MI) has not been clearly determined.Using data from the CRUSADE Registry (Can Rapid Risk Stratification Unstable Angina Patients Suppress Adverse Outcomes With Early Implementation American College Cardiology/American Heart Association Guidelines) linked with Medicare claims, we studied patients ≥65 age MI, discharged on therapy and alive later without recurrent MI to evaluate dose (none, <50%, ≥50% recommended...
BackgroundIn-hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) is higher those COVID-19 than without COVID-19. The factors that predispose to this rate and their relative contribution are poorly understood. This study developed a risk score inclusive of clinical variables predict in-hospital STEMI.MethodsBaseline demographic, clinical, procedural data from the North American Myocardial Infarction registry were extracted. Univariable logistic regression...
Patients with chronic kidney disease (CKD) have been under-represented in stable ischaemic heart (SIHD) trials despite their heightened risk of cardiovascular mortality. We examine associations between disease, treatment selection, and long-term survival patients SIHD. SIHD angiographically significant stenosis (≥70%) were categorized by renal function [dialysis-dependent, severe CKD [estimated glomerular filtration rate (eGFR) < 30], mild-moderate (eGFR 30-59), no ≥ 60)] groups...
BACKGROUND Severe anemia in children is a major public health problem sub‐Saharan Africa. In this study we describe clinical and operational aspects of blood transfusion admitted to Coast Provincial General Hospital, Kenya. STUDY DESIGN AND METHODS This was an observational where over 2‐year period, demographic laboratory data were collected on all for whom the hospital bank received request. Clinical obtained by retrospective review case notes first year. RESULTS There 2789 requests (median...
A pharmacoinvasive (PI) strategy for early presenting ST-segment elevation myocardial infarction nominally reduced 30-day cardiogenic shock and congestive heart failure compared with primary percutaneous coronary intervention (PPCI). We evaluated whether infarct size (IS) was related to this finding.Using the peak cardiac biomarker in patients randomized PI versus PPCI within Strategic Reperfusion Early After Myocardial Infarction (STREAM) trial, IS divided into 3 groups: small (≤2 times...
Background Cardiac intensive care units were originally created in the prerevascularization era for early recognition of ventricular arrhythmias following a myocardial infarction. Many patients with stable ST-segment-elevation infarction (STEMI) are still routinely triaged to cardiac after primary percutaneous coronary intervention (pPCI), independent clinical risk or provision critical therapies. The aim this study was determine factors associated in-hospital adverse events hemodynamically...