A5019953837- Neuroscience and Neural Engineering
- Wireless Power Transfer Systems
- Energy Harvesting in Wireless Networks
- EEG and Brain-Computer Interfaces
- Neurological disorders and treatments
- Wireless Body Area Networks
- Advanced Memory and Neural Computing
- Vagus Nerve Stimulation Research
- Transcranial Magnetic Stimulation Studies
- Advanced Sensor and Energy Harvesting Materials
- Innovative concrete reinforcement materials
- Structural Behavior of Reinforced Concrete
- Optical measurement and interference techniques
- Electrohydrodynamics and Fluid Dynamics
- Concrete Corrosion and Durability
- IoT and Edge/Fog Computing
- Hydraulic and Pneumatic Systems
- Nerve injury and regeneration
- Anesthesia and Pain Management
- Wireless Networks and Protocols
- Perovskite Materials and Applications
- Advanced Data Storage Technologies
- Hygrothermal properties of building materials
- Molecular Communication and Nanonetworks
- ECG Monitoring and Analysis
Rice University
2021-2025
Baylor College of Medicine
2024
University of Michigan
2020-2021
Objective. Carbon fiber electrodes may enable better long-term brain implants, minimizing the tissue response commonly seen with silicon-based electrodes. The small diameter high-channel count brain-machine interfaces capable of reproducing dexterous movements. Past carbon exhibited both high fidelity single unit recordings and a healthy neuronal population immediately adjacent to recording site. However, yield our arrays chronically implanted in typically hovered around 30%, for previously...
Miniaturized neuromodulation systems could improve the safety and reduce invasiveness of bioelectronic neuromodulation. However, as implantable devices are made smaller, it becomes difficult to store enough power for long-term operation in batteries. Here, we present a battery-free epidural cortical stimulator that is only 9 millimeters width yet can safely receive wireless using magnetoelectric antennas deliver 14.5-volt stimulation bursts, which enables stimulate activity on-demand through...
Bioelectric medicine treatments target disorders of the nervous system unresponsive to pharmacological methods. While current stimulation paradigms effectively treat many disorders, underlying mechanisms are relatively unknown, and neuroscience recording electrodes often limited in their specificity gross averages across neurons or axons. Here, we develop a novel, durable carbon fiber electrode array adaptable neural structures for precise recording. Carbon fibers ( [Formula: see text]...
This paper presents the design, implementation, and experimental evaluation of a wireless biomedical implant platform exploiting magnetoelectric effect for power bi-directional communication. As an emerging transfer method, is promising mm-scaled bio-implants because its superior misalignment sensitivity, high efficiency, low tissue absorption compared to other modalities [46, 59, 60]. Utilizing same physical mechanism communication critical miniaturization, but low-power uplink has not been...
Wireless, batteryless, and miniaturized implants promise transformative therapies for various neurological, psychiatric, cardiac disorders. Beyond conventional battery-powered bulky with leads, drastically reduced infection risk surgical complexity, improved patient acceptance precision. Despite significant efforts on wireless power transfer (WPT) implants, most demonstrations are not sufficiently reliable to sustain practical usage, when misalignment between the external hub implant...
Bioelectronic implants transform clinical therapies by offering unprecedented tools for precise sensing and intervention inside the human body. Wireless, battery-free, miniaturized (mm-scale) bio-implants are highly desirable to enhance safety, simplify surgery, minimize behavioral disruptions, boost long-term stability over conventional bulky [1–3]. Developing such devices faces two crucial challenges: safe reliable wireless power transfer (WPT) efficient bidirectional telemetry....
<title>Abstract</title> Networks of miniature bioelectronic implants would enable precise measurement and manipulation the complex distributed physiological systems in body. For example, sensing stimulation nodes throughout heart, brain, or peripheral nervous system more accurately track treat disease support prosthetic technologies with many degrees freedom. A main challenge to creating this type in-body network is fact that wireless power data transfer are often inefficient when...
Abstract Refractory neurological and psychiatric disorders are increasingly treated with brain stimulation therapies using implanted neuromodulation devices. Current commercially available systems, however, limited by the need for implantable pulse generators wired power; complexity of this architecture creates multiple failure points including lead fractures, migration, infection. Enabling less invasive approaches could increase access to these therapies. Here we demonstrate first...
Magnetoelectric power transfer has shown remarkable promise for the development of wireless millimetric bioelectronic implants with its low tissue absorption, high efficiency, and misalignment sensitivity. Utilizing same physical mechanism communication is critical implant miniaturization. For first time, we designed demonstrated near-zero magnetoelectric backscatter from mm-sized by exploiting converse magnetostriction effects. The prototype system consists an 8.2-mm3 integrating...
Intrafascicular peripheral nerve interfaces (PNIs) with penetrating electrodes have the potential to chronically record from nerves on scale of single axons. The small size and dynamic environment makes material selection important for these devices. In this work, we describe how bending properties common PNI electrode materials contribute their effectiveness as self-inserting PNIs. First, tungsten, platinum-iridium, carbon fiber wires are tested assess ability survive repeated stresses when...
Abstract Minimally invasive neural interfaces can be used to diagnose, manage, and treat many disorders with substantially reduced risks of surgical complications. Endovascular implanted in the veins or arteries is one approach, but it requires prescriptions anti-thrombotic medication are likely not explantable after endothelialization. More critically, approach limited by small size location blood vessels, such that important cortical, subcortical, spinal targets cannot reached. Here, we...
Bioelectronic devices that manipulate and record human neural activity could help patients suffering from debilitating health conditions not effectively treated by drugs. Here we discuss the exponential growth in both neuroscience neurotechnology provides ingredients to fuel of implantable as therapeutic options, implications this has on circuit design for neurotech applications.
Wireless minimally invasive bioelectronic implants enable a wide range of applications in healthcare, medicine, and scientific research. Magnetoelectric (ME) wireless power transfer (WPT) has emerged as promising approach for powering miniature bio-implants because its remarkable efficiency, safety limit, misalignment tolerance. However, achieving low-power high-quality uplink communication using ME remains challenge. This paper presents pulse-width modulated (PWM) backscatter enabled by...
Miniature bioelectronic implants promise revolutionary therapies for cardiovascular and neurological disorders. Wireless power transfer (WPT) is a significant method miniaturization, eliminating the need bulky batteries in today's devices. Despite successful demonstrations of millimetric battery-free animal models, robustness efficiency WPT are known to degrade significantly under misalignment incurred by body movements, respiration, heart beating, limited control implant orientation during...
Wireless communication technologies for bioelectronic implants enable remote monitoring diagnosis and adaptive therapeutic intervention without the constraints of wired connections. However, wireless data uplink from millimeter-scale devices deep in body struggles to achieve low power consumption while maintaining large misalignment tolerances. Here, we report a passive backscatter system based on magnetoelectric transducers that consumes less than 0.3 pJ/bit achieves 1E-6 bit error rate at...
Abstract Bioelectric medicine treatments target disorders of the nervous system unresponsive to pharmacological methods. While current stimulation paradigms effectively treat many disorders, underlying mechanisms are relatively unknown, and neuroscience recording electrodes often limited in their specificity gross averages across neurons or axons. Here, we develop a novel, durable carbon fiber electrode array adaptable neural structures for precise recording. Carbon fibers were sharpened...
State‐of‐the‐art intraneural peripheral nerve electrodes are large, silicon‐based structures that can cause substantial tissue response and ill‐suited for recording from small autonomic nerves. The focus of this work is to adapt our minimally‐scarring carbon fiber brain a chronic array. objective study increase the durability withstand surgical handling necessary implantation, while maintaining cellular scale electrode insert through outer epineurium layer Toward end, we embedded fibers in...
The rise in popularity of mass timber structures globally has increased the demand for high-performance connections. Glued-in rod connections which are advantageous compared to other dowel-type because their high strength and stiffness, have been subject extensive research literature; However, lack an in-depth understanding behavior a uniform set guidelines design continues limit use glued-in rods practice. To develop improved connections, this paper examines distributed fiber optic sensors...