Patrick J. Karas

ORCID: 0000-0002-2605-8820
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About
Contact & Profiles
Research Areas
  • Neurological disorders and treatments
  • Vascular Malformations Diagnosis and Treatment
  • Intracranial Aneurysms: Treatment and Complications
  • Multisensory perception and integration
  • Meningioma and schwannoma management
  • EEG and Brain-Computer Interfaces
  • Glioma Diagnosis and Treatment
  • Epilepsy research and treatment
  • Botulinum Toxin and Related Neurological Disorders
  • Cerebrospinal fluid and hydrocephalus
  • Functional Brain Connectivity Studies
  • Bone Tumor Diagnosis and Treatments
  • Neural dynamics and brain function
  • Visual perception and processing mechanisms
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Neuroscience and Neural Engineering
  • Pain Mechanisms and Treatments
  • Head and Neck Surgical Oncology
  • Transcranial Magnetic Stimulation Studies
  • CNS Lymphoma Diagnosis and Treatment
  • Parkinson's Disease Mechanisms and Treatments
  • History of Medical Practice
  • Brain Metastases and Treatment
  • Polyomavirus and related diseases
  • Pharmacological Effects and Toxicity Studies

The University of Texas Medical Branch at Galveston
2022-2025

Neurological Surgery
2014-2024

Baylor College of Medicine
2016-2022

Texas Children's Hospital
2019

The University of Texas MD Anderson Cancer Center
2017

Columbia University Irving Medical Center
2013-2016

Cornell University
2014

The Neurological Institute
2013

The superior frontal gyrus (SFG) is an important region implicated in a variety of tasks including motor movement, working memory, resting‐state, and cognitive control. A detailed understanding the subcortical white matter SFG could improve postoperative morbidity related to surgery around this gyrus. Through DSI‐based fiber tractography validated by gross anatomical dissection, we characterized tracts based on their relationships other well‐known neuroanatomic structures. Diffusion imaging...

10.1002/ca.23523 article EN Clinical Anatomy 2019-11-21

Visual information about speech content from the talker's mouth is often available before auditory voice. Here we examined perceptual and neural responses to words with without this visual head start. For both types of words, perception was enhanced by viewing face, but enhancement significantly greater for a Neural were measured electrodes implanted over association cortex in posterior superior temporal gyrus (pSTG) epileptic patients. The presence suppressed speech, more so We suggest that...

10.7554/elife.48116 article EN cc-by eLife 2019-08-07

INTRODUCTION: Surgical removal of the epileptogenic zone (EZ) after iEEG evaluation is most successful approach for achieving seizure control in drug-resistant patients. Although automated algorithms EZ localization hold potential, issues like technical complexity and reproducibility hurdles limit their clinical adoption. METHODS: We developed a module called FREEZ (Frequency Range Explorer to assist Epileptogenic Zone localization) within open-source platform RAVE, enabling visualization...

10.1227/neu.0000000000003360_1004 article EN Neurosurgery 2025-03-14

Background and Purpose— Level of consciousness is frequently assessed by command-following ability in the clinical setting. However, it unclear what brain circuits are needed to follow commands. We sought determine networks differentiate command following from noncommand patients after hemorrhagic stroke. Methods— Structural MRI, resting-state functional electroencephalography were performed on 25 awake unresponsive with acute intracerebral subarachnoid hemorrhage. injury was via volumetric...

10.1161/strokeaha.114.007645 article EN Stroke 2014-12-10

Experimentalists studying multisensory integration compare neural responses to stimuli with the component modalities presented in isolation. This procedure is problematic for speech perception since audiovisual and auditory-only are easily intelligible but visual-only not. To overcome this confound, we developed intracranial encephalography (iEEG) deconvolution. Individual always contained both auditory visual speech, jittering onset asynchrony between allowed time course of unisensory...

10.1523/jneurosci.0279-20.2020 article EN cc-by Journal of Neuroscience 2020-07-29

A number of stereotactic platforms are available for performing deep brain stimulation (DBS) lead implantation. Robot-assisted stereotaxy has emerged more recently demonstrating comparable accuracy and shorter operating room times compared with conventional frame-based systems.To compare the our streamlined robotic DBS workflow data in literature from frameless systems.We retrospectively reviewed 126 consecutive placement procedures using a platform. Indications included Parkinson disease (n...

10.1227/ons.0000000000000298 article EN Operative Neurosurgery 2022-06-14

10.1055/s-0045-1803969 article EN Journal of Neurological Surgery Part B Skull Base 2025-02-01

Charles Bonnet Syndrome (CBS) is a condition characterized by complex visual hallucinations in individuals with impairment. We present the case of patient bilateral optic atrophy secondary to obstructive hydrocephalus caused pineal parenchymal tumor intermediate differentiation (PPTID) who experienced formed consistent CBS. Following right occipital craniotomy for transtentorial approach and resection, she developed elementary hallucinations. A thorough clinical history systematic diagnostic...

10.1016/j.ebr.2025.100764 article EN cc-by-nc-nd Epilepsy & Behavior Reports 2025-04-01

OBJECTIVE This study evaluated the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1-RAs) in idiopathic intracranial hypertension (IIH), focusing on their effects clinical outcomes, management escalation, and mortality. METHODS The authors conducted a cohort using TriNetX Research Network, comparing IIH patients treated with GLP-1-RAs to untreated patients, employing propensity score matching. Clinical including headaches, visual cognitive deficits, acetazolamide use, surgery,...

10.3171/2025.1.jns242357 article EN Journal of neurosurgery 2025-05-01

BACKGROUND: Surgery has become integral in treating children with tuberous sclerosis complex (TSC)–related drug-resistant epilepsy (DRE). OBJECTIVE: To describe outcomes of a multimodal diagnostic and therapeutic approach comprising invasive intracranial monitoring surgical treatment compare the complementary techniques open resection magnetic resonance–guided laser interstitial thermal therapy. METHODS: Clinical radiographic data were prospectively collected for pediatric patients...

10.1227/neu.0000000000002214 article EN Neurosurgery 2022-11-10

A middle-aged patient presented with right-sided chemosis, exophthalmos, and progressive visual loss. Digital subtraction angiography revealed a type D carotid-cavernous fistula (CCF). Transarterial embolization through the internal maxillary artery was unsuccessful, there no venous access to CCF. robotic-guided direct transtemporal of CCF Onyx performed, resulting in successful obliteration symptom resolution. This is first reported case transcranial embolization. We include technical video...

10.1136/jnis-2022-019868 article EN Journal of NeuroInterventional Surgery 2023-01-10

The authors present the first report of laser interstitial thermal therapy (LITT) ablation a recurrent chordoma metastasis to cervical spine. This patient was 75-year-old woman who diagnosed and treated for sacral chordoma, then developed metastases lung upper thoracic Unfortunately she experienced symptomatic recurrence at C-7 spinous process. She underwent an uncomplicated LITT lesion. convalesced without incident discharged on postoperative Day 1. received stereotactic spinal radiosurgery...

10.3171/2016.11.spine16897 article EN Journal of Neurosurgery Spine 2017-03-01

The classic presentation of a carotid-cavernous fistula (CCF) is unilateral painful proptosis, chemosis, and vision loss. Just as the goal treatment for dural arteriovenous (dAVF) obliteration entire fistulous connection proximal draining vein, modern CCF endovascular occlusion cavernous sinus via transvenous or transarterial route. Here, authors present case woman with paracavernous dAVF mimicking clinical radiographic CCF. Without any route available to access venous drainage, devised...

10.3171/2020.7.jns201737 article EN Journal of neurosurgery 2020-11-13
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