A5056162051- Traditional Chinese Medicine Analysis
- Andrographolide Research and Applications
- Lipid metabolism and disorders
- Acute Kidney Injury Research
- Kawasaki Disease and Coronary Complications
- Paraquat toxicity studies and treatments
- Helicobacter pylori-related gastroenterology studies
- Inflammation biomarkers and pathways
Chengdu University of Traditional Chinese Medicine
2020
Henan University Huaihe Hospital and Huaihe Clinical Institute
2019
Shanghai Changzheng Hospital
1997
Background: Andrographolide (Andro) is an active compound extracted from Andrographis, which has protective anti-inflammatory effects. But, its pathological role in coronary heart disease (CHD) unclear, the aim of this study to investigate therapeutic effect Andro CHD and explore potential mechanism. Methods: Here, we established a mouse model CHD, rats were randomly divided into 5 groups (n=10): sham, (50 mg/kg), + (10 mg/kg). HE staining was employed evaluate changes myocardial injury...
Abstract Cryptotanshinone (CTS), an active component extracted from the root of Salvia miltiorrhiza Bunge , was reported to attenuate hepatic ischemia/reperfusion (I/R) injury. However, its protective effect against renal I/R injury remains unclear. In this study, role CTS in vitro and possible mechanism were investigated. Our results showed that improved cell viability HK‐2 cells exposed hypoxia/reoxygenation (H/R). also inhibited H/R‐mediated production reactive oxygen species, as well...