A5100777972- Cancer Immunotherapy and Biomarkers
- ATP Synthase and ATPases Research
- Plant tissue culture and regeneration
- Prostate Cancer Treatment and Research
- Mitochondrial Function and Pathology
- Nuclear Receptors and Signaling
- Macrophage Migration Inhibitory Factor
- Connexins and lens biology
- Reproductive System and Pregnancy
- Cytokine Signaling Pathways and Interactions
- Heavy metals in environment
- Plant Molecular Biology Research
- Cancer-related molecular mechanisms research
- SARS-CoV-2 and COVID-19 Research
- Heme Oxygenase-1 and Carbon Monoxide
- Genetics and Plant Breeding
- Plant Stress Responses and Tolerance
- Cancer Mechanisms and Therapy
- Nutritional Studies and Diet
- Genetic Mapping and Diversity in Plants and Animals
- Bacillus and Francisella bacterial research
- BRCA gene mutations in cancer
- Lipid metabolism and disorders
- Calpain Protease Function and Regulation
- SARS-CoV-2 detection and testing
Ocean University of China
2022-2024
Chinese Center For Disease Control and Prevention
2017-2024
Nanyang Technological University
2019-2024
National Center for Immunization and Respiratory Diseases
2023
Huazhong University of Science and Technology
2020-2023
Harbin Medical University
2019-2022
Rush University Medical Center
2014-2022
Huazhong Agricultural University
2022
First Affiliated Hospital of Harbin Medical University
2019-2022
Qingdao National Laboratory for Marine Science and Technology
2022
Mangrove species are uniquely adapted to tropical and subtropical coasts, although relatively low in number of species, mangrove forests provide at least US $1.6 billion each year ecosystem services support coastal livelihoods worldwide. Globally, areas declining rapidly as they cleared for development aquaculture logged timber fuel production. Little is known about the effects area loss on individual local or regional populations. To address this gap, species-specific information global...
Lower household income has been consistently associated with poorer diet quality. Household food purchases may be an important intervention target to improve quality among low populations. Associations between and the of were examined.Food purchase receipt data collected for 14 days from 202 urban households participating in a study about shopping. Purchase analyzed using NDS-R software scored Healthy Eating Index 2010 (HEI 2010). HEI total subscores, proportion grocery dollars spent on...
We examined whether accordance to the DASH (Dietary Approach Stop Hypertension) and Mediterranean diets is associated with slower cognitive decline in a prospective Chicago cohort study of older persons, Memory Aging Project.The sample comprised 826 Project participants (aged 81.5 ± 7.1 years) who completed 144-item food frequency questionnaire at baseline 2 or more assessments over 4.1 years. Dietary scores were computed for diet (0-10) (MedDietScore) (0-55). For both, higher reflect...
The research of hydrogels has been increasingly focused on designing an effective energy dissipation structure in recent years. Here, we report a kind novel supramolecular cross-linker, which was formed by self-assembling amphiphilic block copolymers with guest groups at the end and vinyl-functionalized cyclodextrin (CD) through host–guest interaction. These cross-linkers could dissipate effectively since they combined multiple sacrificial mechanisms across multiscales physical interactions....
<h3>Background and Objectives</h3> Previous research has examined the association between cognition flavonoids: bioactives found in foods, known to possess anti-inflammatory antioxidant properties. We extend this by investigating associations of dietary intakes total flavonols constituents (kaempferol, quercetin, myricetin, isorhamnetin) on change cognitive performance global cognition, episodic memory, semantic visuospatial ability, perceptual speed, working memory. <h3>Methods</h3> The...
T-cell responses may be shaped by sterile "danger signals" that are constituted damage-associated molecular patterns (DAMP). However, whether and what type of adaptive immune triggered in vivo DAMPs induced tumor progression not well characterized. In this study, we report the production HMGB1, an established DAMP released dying cells, was critical for mouse model prostate cancer. HMGB1 required activation intratumoral accumulation T cells expressed cytokine lymphotoxinα(1)β(2) (LT) on their...
Rapid advancement in genomic technologies has greatly enhanced the potential of clinical recognition and application molecular targets. Specifically, gene mutation detection are great significance early diagnosis, customized drug delivery guidance, treatment progression, monitoring tumor’s resistance. Gene or genetic typing patients is a prerequisite for targeted therapies. Most kinds therapies treat cancers by interfering with specific proteins that involved tumorigenesis. Compared...
Two-dimensional MXene materials with the composition Ti3C2Tx, where T represents a surface termination species, have become popular for many applications due to their large areas, unique mechanical and electrochemical properties, ability create thin single-layer systems. The high area hydrophilicity of this material render it viable option as molecular adsorber in aqueous solutions. In recent studies, using simplified synthesis method called minimally intensive layer delamination, we shown...
This study aimed to evaluate the effects of fermented corn-soybean meal mixed feed on intestinal barrier function and cecal microbiota in laying hens. A total 360 Jingfen No.6 hens (22 wk-old) were assigned 4 dietary treatments, which offered basal diets (without antibiotics) containing 0, 4, 6 8% respectively. The results showed that pH value anti-nutritional factor concentrations lower than those unfermented (p < 0.05). Moreover, fermentation significantly increased crude protein content...
// Xin Men 1 , Jun Ma Tong Wu Junyi Pu Shaojia Wen Jianfeng Shen Xun Wang Yamin Chao Chen and Penggao Dai National Engineering Research Center for Miniaturized Detection Systems, College of Life Sciences, Northwest University, Xi'an, PR China Correspondence to: Dai, email: daipg@nwu.edu.cn Chen, chaochen@nwu.edu.cn Keywords: tamoxifen; resistance; transcriptome; RNA-seq; breast cancer Received: May 24, 2017 Accepted: December 15, Published: 26, ABSTRACT Tamoxifen (TAM) resistance is an...
Project Description: The Mediterranean and DASH dietary patterns have been associated with slower rate of cognitive decline. diet reflects a culturally-based pattern whereas the was devised initially to reduce blood pressure. Neither is specific current knowledge on neuroprotective foods nutrients. We new score, MIND that more specifically captures consumption individual nutrients related decline incident dementia. includes many same components as in diets, such emphasis natural plant-based...
Toxic heavy metal pollution of water is a major environmental problem and the current remediation approaches are not optimal as they non-eco-friendly lacking in efficiency. As such phytoremediation, green technology recognized better approach. In this study, both Fourier Transform Infrared (FTIR) Spectroscopy Inductive Coupled Plasma-Optical Emission (ICP-OES) were used to investigate capability an aquatic plant, hyacinth (Eichhornia crassipes) remove metals lead, copper, cadmium arsenic...
Polysaccharide from the edible alga Enteromorpha clathrata has been demonstrated to exert beneficial effects on human health. However, what effect it inflammatory bowel diseases not investigated. Here, using a mouse model of dextran sulfate sodium (DSS)-induced ulcerative colitis, we illustrate that polysaccharide (ECP) could alleviate body weight loss, reduce incidences colonic bleeding, improve stool consistency and ameliorate mucosal damage in diseased mice. 16S rRNA high-throughput...
Testicular cancer is a very common malignancy in young men. Although testicular has high cure rate, patients have long-term risk of secondary malignant tumors and cardiovascular disease. In addition, for resistant to traditional treatment methods, new methods predicting prognosis are also urgently needed.Gene expression profiles 165 normal tissues 156 germ cell tumor (TGCT) from GTEx database TCGA were used obtain differentially expressed genes (DEGs) TGCT. Through the ImmPort database, we...
The mitochondrial ATP synthase is a molecular motor, which couples the flow of protons with phosphorylation ADP. Rotation central stalk within core effects conformational changes in active sites driving synthesis ATP. Mitochondrial genome integrity (mgi) mutations have been previously identified alpha-, beta-, and gamma-subunits yeast Kluyveromyces lactis trypanosome Trypanosoma brucei. These reverse lethality loss DNA petite negative strains. Introduction homologous Saccharomyces cerevisiae...
Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. 5-fluorouracil (5-FU)-based chemotherapeutic regimens are routinely used for treatment patients with CRC. However, recurrence and drug resistance limit survival rates DNA methylation participates in diverse cellular processes by regulating transcription a large number genes expression, cell division, apoptosis, adhesion differentiation, metabolism, thus it might mediate chemoresistance. Using an Illumina...
Cervical cancer is one of the most fatal malignancies in females. Acquired resistance to chemotherapeutic agent reason behind this lethality. In study, we developed cisplatin cell line, subsequently examined molecular mechanisms linked. Transcriptome sequencing technology was utilized compare various expression models between cisplatin-resistant line (Hela/DDP) and its parental human cervical adenocarcinoma Hela. The present study has identified 2,312 differentially expressed genes (DEGs)....
Abstract Single molecule studies in recent decades have elucidated the full chemo-mechanical cycle of F 1 -ATPase, mostly based on from thermophilic bacteria. In contrast, high-resolution crystal structures are only available for mitochondrial . Here we present high resolution single rotational data Saccharomyces cerevisiae , obtained using new throughput detection and analysis tools. Rotational presented wild type enzyme, a “liver” isoform six mutant forms yeast that previously been...