A5041718044- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Probiotics and Fermented Foods
- Gut microbiota and health
- Enzyme Production and Characterization
- Methane Hydrates and Related Phenomena
- Natural Language Processing Techniques
- Speech Recognition and Synthesis
- Seaweed-derived Bioactive Compounds
- Topic Modeling
- Polysaccharides and Plant Cell Walls
- Fibroblast Growth Factor Research
- Microbial bioremediation and biosurfactants
- Multimodal Machine Learning Applications
- Polyamine Metabolism and Applications
- Diet and metabolism studies
- Human Pose and Action Recognition
- Gout, Hyperuricemia, Uric Acid
- Anomaly Detection Techniques and Applications
- Toxic Organic Pollutants Impact
- Soil and Unsaturated Flow
- Climate change and permafrost
- Proteoglycans and glycosaminoglycans research
- Electrochemical sensors and biosensors
- Environmental Changes in China
Qingdao University
2025
Affiliated Hospital of Qingdao University
2025
Shanghai Artificial Intelligence Laboratory
2024
Beijing Academy of Artificial Intelligence
2024
Qingdao University of Technology
2020-2024
State Key Laboratory of Pollution Control and Resource Reuse
2024
Tongji University
2024
Qingdao National Laboratory for Marine Science and Technology
2022-2023
Laoshan Laboratory
2023
Ocean University of China
2018-2023
Alginate has been documented to prevent the development and progression of ulcerative colitis by modulating gut microbiota. However, bacterium that may mediate anti-colitis effect alginate not fully characterized. We hypothesized alginate-degrading bacteria might play a role here since these could utilize as carbon source. To test this hypothesis, we isolated 296 strains from human gut. Bacteroides xylanisolvens AY11-1 was observed have best capability for degradation. The degradation...
Previous studies have suggested that polysaccharide from Enteromorpha clathrata (ECP) could be used as a potential prebiotic to treat dysbiosis-associated diseases. However, whether it has any therapeutic effects on obesity not been investigated. In the present study, we explored anti-obesity effect of ECP and illustrated can significantly reduce body weight decrease serum levels triacylglycerol cholesterol in high-fat diet (HFD)-fed mice. As revealed by 16S rRNA high-throughput sequencing...
Large Language Models (LLMs) have attracted extensive attention due to their remarkable performance across various tasks. However, the substantial computational and memory requirements of LLM inference pose challenges for deployment in resource-constrained scenarios. Efforts within field been directed towards developing techniques aimed at enhancing efficiency inference. This paper presents a comprehensive survey existing literature on efficient We start by analyzing primary causes...
The human gut microbiota plays a critical role in the metabolism of dietary carbohydrates. Previous studies have illustrated that marine algae oligosaccharides could be utilized and readily fermented by microbiota. However, is classified into three different enterotypes, how this may affect fermentation processes has not been studied. Here, using vitro 16 S high-throughput sequencing techniques, we demonstrate an enterotype-specific effect on outcomes oligosaccharides. Notably, with...
Alginate, a bioactive polysaccharide fermentable by gut microbiota, has been shown to effectively reduce serum uric acid levels. However, its mechanisms and the role of microbiota remain unclear. In this study, we explored effects alginate with two different molecular weights on hyperuricemia mice. Both alginates exhibited potent hypouricemic through ABCG2 transporter upregulation, ameliorating hyperuricemia-induced renal intestinal dysfunctions, low-molecular-weight demonstrating enhanced...
A Gram-stain-negative, strictly aerobic, non-motile, long, straight-rod and non-flagellated marine bacterium strain, designated SCR12 T , was isolated from the gill of a shrimp collected in Tangyin hydrothermal field Okinawa Trough. The growth temperature range 16–40 °C optimum 37 °C. Optimal occurred at pH 6.5 presence 3 % (w/v) NaCl. predominant isoprenoid quinone strain menaquinone-6 (MK-6). fatty acids (>10 %) were iso-C 15 : 0 (44.2 %), 1 G (19.0 17 3-OH (12.1 %). major polar lipids...
Polysaccharide from the edible alga Enteromorpha clathrata has been demonstrated to exert beneficial effects on human health. However, what effect it inflammatory bowel diseases not investigated. Here, using a mouse model of dextran sulfate sodium (DSS)-induced ulcerative colitis, we illustrate that polysaccharide (ECP) could alleviate body weight loss, reduce incidences colonic bleeding, improve stool consistency and ameliorate mucosal damage in diseased mice. 16S rRNA high-throughput...
Sparse attention can effectively mitigate the significant memory and throughput demands of Large Language Models (LLMs) in long contexts. Existing methods typically employ a uniform sparse mask, applying same pattern across different heads input lengths. However, this approach fails to capture diverse patterns inherent LLMs, ignoring their distinct accuracy-latency trade-offs. To address challenge, we propose Mixture Attention (MoA), which automatically tailors configurations layers. MoA...
In order to improve the practicality of rapid biochemical oxygen demand (BOD) method, a highly sensitive detection method for BOD that is based on establishing correlation between current and dissolved (DO) was developed. this experiment, Bacillus subtilis used as test microorganism, embedding achieve quantitative fixation microorganisms, which could increase content microorganisms prolong service life biological element. The conductivity (COND) probe sensing element, so testing value can be...
A Gram-stain-negative, facultative anaerobic, non-motile, short-clavate and non-flagellated marine bacterium strain, designated JC075T, was isolated from the Yongle Blue Hole in South China Sea. Based on 16S rRNA gene sequence, strain JC075T found to be closely related Marinifilum albidiflavum FB208T (97.10 %), flexuosum DSM 21950T (96.43 %) fragile JCM 15579T (95.58 with less than 90.24 % sequence similarity other genera of family Marinifilaceae. The growth temperature range 10-37 °C,...
Blue holes are unique geomorphological units characterized by steep redox and biogeochemical gradients. Yongle Hole is located on the largest atoll (Yongle Atoll) of western Xisha Islands in South China Sea. A Gram-stain-negative, facultatively anaerobic, non-motile, non-flagellated marine bacterium with creamy white colonies, designated JC036T, was isolated from Hole. Cells were short-rod-shaped catalase-negative. 16S rRNA gene sequence analysis showed that similarities lower than 91.6 %...
A Gram-stain-negative, strictly aerobic, oval-shaped, non-motile bacterium with no flagella, designated strain SCR17 T , was isolated from a shrimp gill habitat in Tangyin hydrothermal field of Okinawa Trough. Phylogenetic analysis based on 16S rRNA gene sequences indicated that formed lineage within the family ‘ Rhodobacteraceae ’, and shared sequence similarity 93.2–96.2 % to related genera Aquicoccus Roseivivax . Strain able grow 0–14 (w/v) NaCl (optimum, 9–10 %). The sole respiratory...
A Gram-stain-negative, strictly aerobic, motile by gliding, rod-shaped and non-flagellated marine bacterium strain, designated BOM4 T , was isolated from a mussel inhabiting the Tangyin hydrothermal field of Okinawa Trough. The growth temperature in range 16–40 °C, optimum 37 °C. Optimal occurred at pH 7.0 presence 1 % (w/v) NaCl. predominant isoprenoid quinone strain identified as menaquinone-6 (MK-6). fatty acids (>10 %) were iso-C 15 : 0 (43.8 17 3-OH (17.5 %). major polar lipids...
A Gram-stain-negative, non-motile, facultatively anaerobic and non-flagellated marine bacterium, designated JC070T was isolated from the Yongle Blue Hole in South China Sea. The temperature, pH NaCl ranges for growth of strain were 4-37 °C (optimum, 16 °C), 6.0-9.0 7.0) 1.0 -6.0% (w/v; optimum, 3.0%). predominant isoprenoid quinone identified as menaquinone-7. dominant fatty acids (>10%) iso-C15:0 (59.6%) iso-C17:0 3-OH (17.2%). major polar lipids aminophospholipid, aminolipid, two unknown...
A Gram-stain-negative, obligately anaerobic, non-motile, non-spore-forming, long-rod-shaped and non-flagellated bacterial strain, designated T3-2 S1-CT, was isolated from a sediment sample collected at the Okinawa Trough. Phylogenetic analyses of 16S rRNA gene sequences whole genome revealed that strain S1-CT member family Marinifilaceae exhibited less than 95.1 % sequence similarities to closely related type strains Marinifilaceae. Optimal growth occurred pH 7.0, 28 °C in presence 3 (w/v)...