- Renal Diseases and Glomerulopathies
- Wildlife Ecology and Conservation
- Dialysis and Renal Disease Management
- Species Distribution and Climate Change
- Hepatocellular Carcinoma Treatment and Prognosis
- Chronic Kidney Disease and Diabetes
- Therapeutic Uses of Natural Elements
- Magnesium in Health and Disease
- Family Caregiving in Mental Illness
- Sulfur Compounds in Biology
- Organ Donation and Transplantation
- Autophagy in Disease and Therapy
- Rangeland Management and Livestock Ecology
- Vasculitis and related conditions
- Network Security and Intrusion Detection
- Cardiac tumors and thrombi
- Diverticular Disease and Complications
- Mycorrhizal Fungi and Plant Interactions
- IgG4-Related and Inflammatory Diseases
- Platelet Disorders and Treatments
- Pediatric health and respiratory diseases
- Alcohol Consumption and Health Effects
- Bipolar Disorder and Treatment
- Insect Utilization and Effects
- Genomics and Phylogenetic Studies
China Medical University
2011-2025
Zhujiang Hospital
2025
Southern Medical University
2024-2025
Shanghai University of Medicine and Health Sciences
2024
Northeast Forestry University
2023-2024
Hainan General Hospital
2024
Hainan Medical University
2024
Capital Medical University
2021-2022
Beijing Chao-Yang Hospital
2021-2022
Shaanxi University of Chinese Medicine
2021
Following the 2019 coronavirus disease (COVID-19) outbreak in China, undergraduate students may experience psychological changes. During emergency circumstances, social support is an important factor influencing mental health condition among Shaanxi province. This study aims to find factors associated with symptoms of depression, anxiety, and stress province during COVID-19 pandemic China. A cross-sectional was conducted from Feb 23 Mar 7, 2020. total 1278 universities located participated...
Bladder cancer (BCa) exhibits the escalating incidence and mortality due to untimely inaccurate early diagnosis. Urinary exosome metabolites, carrying critical tumor cell information directly related bladder, emerge as promising non-invasive diagnostic biomarkers of BCa. Herein, magnetic 3D ordered macroporous zeolitic imidazolate framework-8 (magMZIF-8) is synthesized used for efficient urinary isolation. Notably, beyond retaining single crystals micropores conventional ZIF-8, MZIF-8...
Anti-partial epithelial-mesenchymal transition (pEMT) treatment of renal tubular epithelial cells (TECs) represents a promising therapeutic approach. Hyperuricemia nephropathy (HN) arises as consequence hyperuricemia (HUA)-induced tubulointerstitial fibrosis (TIF). Studies have suggested that the Ras homolog member A (RhoA)/Rho-associated kinase (ROCK) pathway is crucial signaling transduction system in fibrosis. Fasudil, RhoA/ROCK inhibitor, has exhibited potential to prevent progress....
Zinc (Zn) and magnesium (Mg) are essential trace elements in humans. Their deficiency may be associated with inflammation oxidative stress (OS) patients diabetic nephropathy (DN), but the mechanisms involved have not been fully characterized. We aimed to investigate relationships between circulating concentrations of Zn Mg pro-inflammatory factors DN-associated renal functional damage type 2 diabetes mellitus (T2DM). To this end, we studied 20 healthy people, 24 T2DM, 59 T2DM T2DN. Serum...
Laparoscopic caudate lobectomy (LCL) is one of the most challenging types laparoscopic liver resections. The main difficulty lies in deep anatomical position lobe, which closely adjacent to first and second hepatic ports inferior vena cava, increasing risk major bleeding during surgery. In addition a thorough understanding anatomy lobe tumor, comprehensive imaging assessment, three-dimensional reconstruction, flexible choice surgical approach also key reducing improving safety. We perform...
In recent years, triple therapy (molecular targeted agent + PD-1 inhibitor transarterial therapy) has emerged as a promising strategy for unresectable hepatocellular carcinoma (uHCC). However, the optimal molecular choice within remains unclear. Donafenib is currently only drug with superior survival benefits compared sorafenib monotherapy. This study aimed to compare donafenib-based versus sorafenib-based in patients uHCC, providing preliminary evidence guide selection this emerging...
4128 Background: Microvascular invasion (MVI) is currently recognized as a pathological feature strongly associated with HCC recurrence. However, its predictive performance in clinical practice remains suboptimal. The detection of minimal residual disease (MRD), which has demonstrated significant prognostic value across multiple cancer types, represents promising alternative. Therefore, the first goal this study to detail genomic alterations that potentially drive MVI or MRD, second aims...
Hepatocellular carcinoma (HCC) is associated with a high rate of postoperative recurrence. Postoperative adjuvant transcatheter arterial chemoembolization (PA-TACE) effective in preventing However, the effect different courses PA-TACE on tumor prognosis remains unclear. As such, this study aimed to develop and validate nomogram that incorporates predict early Data from 307 high-risk patients who underwent were divided into training test cohorts at 6:4 ratio. A was developed group using least...
Depression is one of the most important psychiatric disorders in chronic kidney disease patients who undergo maintenance hemodialysis (MHD). Previous studies have shown that low-grade inflammation involved progression depressive symptoms. The neutrophil-to-lymphocyte ratio (NLR) an inflammatory marker inexpensive and easy to measure. However, association between NLR depression symptoms MHD has not been examined.In this single-center, cross-sectional study, we included 160 undergoing MHD....
The gasotransmitter hydrogen sulfide (H2S) plays important physiological and pathological roles in the cardiovascular system. However, involvement of H2S recovery from uremic cardiomyopathy (UCM) remains unclear. This study aimed to determine therapeutic efficacy elucidate underlying mechanisms UCM. A UCM model was established by 5/6 nephrectomy 10-week-old C57BL/6 mice. Mice were treated with sodium hydrosulfide (NaHS, donor), L-cysteine [L-Cys, cystathionine gamma-lyase (CSE) substrate],...
Cognitive impairment and depression are common mental health problems in chronic kidney disease (CKD) patients with maintenance hemodialysis (MHD). Previous studies have proven that cognitive were risk factors for poor prognosis MHD patients. However, the related of function association between still unclear. The purpose this study is to explore affecting evaluate relationship patients.This single-center, cross-sectional enrolled 160 depressive symptoms measured using Montreal Assessment...
Climate change is becoming an important driver of biodiversity loss by altering the habitat, distribution and interspecific relationships species. Japanese yew (Taxus cuspidata) a first class protected plant in China, which has ecological significance occupies certain position feeding habit wapiti (Cervus elaphus) Siberian roe deer (Capreolus pygargus). Due to human animal damage, number gradually decreased. Therefore, understanding potential suitable areas for browse on it under climate...
Beta2-microglobulin, a novel marker of kidney function, predicts failure and mortality in the general population. However, few studies have evaluated association serum β2-MG level with clinical outcome maintenance hemodialysis (MHD) patients.This prospective cohort study enrolled 303 MHD patients to investigate factors related its relationship patients. Multivariate linear regression analysis was used examine level. Multivariable Cox calculate hazard ratios for on all-cause cardiovascular...
IgG4-related disease (IgG4-RD) is a slowly progressing inflammatory that can involve multiple organ systems. There considerable overlap between IgG4-RDs and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Herein, we present an unusual case of IgG4-associated tubulointerstitial nephritis (IgG4-TIN) ANCA-associated glomerulonephritis (ANCA-GN) co-occurring with C3 (C3GN).A 72-year-old male was admitted to hospital because fever fatigue. He diagnosed elevated serum...
Habitat isolation and fragmentation are serious to Amur tiger in the eastern Wandashan Mountains China. patches isolated from each other or core area by connected boundaries.These will hinder dispersal migration gene exchange among populations.The unreasonable spatial layout greatly restricts recovery survival of them.Therefore, assessing quality habitat, improving landscape connectivity, promoting construction ecological corridors crucial conservation tiger.We analyze connectivity between...
<title>Abstract</title> Patients with unresectable hepatocellular carcinoma (uHCC) have poor long-term prognosis, necessitating alternative treatment modalities. We assessed the efficacy and safety of tyrosine kinase inhibitors immune checkpoint combined either transarterial chemoembolisation, hepatic artery infusion chemotherapy, or transcatheter arterial embolisation chemotherapy in patients uHCC. The efficacy, represented by survival tumour response, tolerability, adverse event frequency...
Dear Editor, Despite a recent trend toward earlier diagnosis of renal cell carcinoma (RCC), 4–10% patients are still diagnosed with advanced disease and tumor invasion into the inferior vena cava1. Patients kidney cancers, specifically RCCs, at increased risk venous thromboembolism (VTE), rates varying between 1.2 3.5%2,3. To identify preoperative thrombotic factors in cava thrombus, Wang et al.4 performed retrospective case–control study concluded that addition to contributing mechanical...