Guixia Chen

ORCID: 0000-0001-5148-201X
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About
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Research Areas
  • Food Allergy and Anaphylaxis Research
  • Heavy Metal Exposure and Toxicity
  • Allergic Rhinitis and Sensitization
  • Asthma and respiratory diseases
  • Gestational Diabetes Research and Management
  • Financial Markets and Investment Strategies
  • Mercury impact and mitigation studies
  • Infant Nutrition and Health
  • Stochastic processes and financial applications
  • Arsenic contamination and mitigation
  • Environmental remediation with nanomaterials
  • Transportation Planning and Optimization
  • Air Quality and Health Impacts
  • Toxic Organic Pollutants Impact
  • Risk and Portfolio Optimization
  • Pregnancy and preeclampsia studies
  • Building Energy and Comfort Optimization
  • Wastewater Treatment and Nitrogen Removal
  • Trace Elements in Health
  • Infant Development and Preterm Care
  • Breastfeeding Practices and Influences
  • Thermoregulation and physiological responses
  • Birth, Development, and Health
  • Per- and polyfluoroalkyl substances research
  • Contact Dermatitis and Allergies

Friedrich-Alexander-Universität Erlangen-Nürnberg
2025

Universitätsklinikum Erlangen
2025

Xiamen Maternal and Child Health Hospital
2006-2024

Children’s Hospital of Fudan University Xiamen Branch
2020-2024

Xiamen University
2020-2024

Jimei University
2024

Third Affiliated Hospital of Zhengzhou University
2019-2021

Xi'an University of Architecture and Technology
2019-2021

Zhengzhou Children's Hospital
2020

Zhengzhou University
2020

An electrochemically prepared water treatment reagent containing a high concentration of Al(13) polymer and active chlorine (PACC) showed promising potential for the removal As(III) due to combined function oxidation coagulation. The results indicated that PACC was effective through by subsequent As(V) coagulation with polymer. oxidized in PACC, stoichiometric rate 0.99 mg Cl(2)/mg As(III). most Al species responsible PACC. To meet As drinking standards weight ratio Cl(2)/Al within 0.09...

10.1021/es203917g article EN Environmental Science & Technology 2012-05-17

<h3>Importance</h3> It remains unknown whether children born at different degrees of prematurity, early term, and post term might have a higher risk developmental coordination disorder (DCD) compared with completely full-term (39-40 gestational weeks). <h3>Objective</h3> To differentiate between suspected DCD in ages based on national representative sample China. <h3>Design, Setting, Participants</h3> A retrospective cohort study was conducted China from April 1, 2018, to December 31, 2019....

10.1001/jamanetworkopen.2021.37581 article EN cc-by-nc-nd JAMA Network Open 2021-12-14

Aim: The average mercury load in children under 7-years old was determined a populated but not overly industrial coastal area China. Methods: 395 blood samples, 1072 urine and 581 hair samples were collected from 1076 children, aged 0 to 6 years, eight representative communities of Xiamen, Mercury levels the surveyed. Results: 95% upper limits blood, urine, for 2.30, 1.50 2100.00 μg/kg, respectively. Levels tended increase with age. Correlation analyses showed that correlated those (n =...

10.3390/ijerph111112029 article EN International Journal of Environmental Research and Public Health 2014-11-20

Abstract Background mTOR inhibitor therapy is solely monitored via pharmacokinetics after kidney transplantation, which may not accurately reflect the effectiveness of PI3K-Akt-mTOR pathway blockade, potentially leading to inadequate or excessive immunosuppression. The pharmacodynamic effect inhibition on NK cells and dendritic cell subsets renal transplantation has been investigated so far. Methods Phosphoflow cytometry was employed in this cross-sectional study evaluate extent peripheral...

10.1093/cei/uxaf026 article EN Clinical & Experimental Immunology 2025-04-24

In order to reduce the immunoreactivity of sarcoplasmic calcium-binding protein (SCP), site-directed mutations were used replace key amino acids in conformational epitopes and sites. The mutant SCPs (mSCPs) expressed Escherichia coli, their immunoreactivities analyzed using iELISA basophil activation assays. Furthermore, structural changes mSCPs determined from circular dichroism spectra. results showed that could effectively inhibit binding wild-type SCP (wtSCP) sensitive serum, with...

10.1021/acs.jafc.0c05733 article EN Journal of Agricultural and Food Chemistry 2020-12-30

Scy p 8 (triosephosphate isomerase) as a crab allergen in inducing distinct T-helper (Th) cell differentiation and linear epitope associated with allergenicity remain elusive. In this study, mice sensitized exhibited significantly upregulated levels of IgE, IgG1, IL-4 release, Th2 immune response. Moreover, the release IFN-γ (Th1) Treg cells were downregulated, while IL-17A (Th17) was upregulated, indicating that disrupted Th1/Th2 balance Th17/Treg mice. Furthermore, bioinformatics...

10.1021/acs.jafc.4c02693 article EN Journal of Agricultural and Food Chemistry 2024-05-31

Breast milk contains various crucial nutrients and biologically active substances is ideal for newborns. This study aimed to analyze the composition of breast from mothers premature full-term infants its influences on growth infants.

10.1186/s12887-024-04757-4 article EN cc-by BMC Pediatrics 2024-04-30

OBJECTIVE To understand the correlation of blood lead levels in infant, maternal and breast milk as to providing evidence for prevention potential infant hazard from lead. METHODS Lead were measured by using graphite stove atom absorption spectrographic methods milk, infants aged 0 11 months their mothers between November December 2002 Xiamen City. Blood samples collected both mother infant's fingertips. Questionnaires also used collect information about childbirth, mothers, families other...

10.3760/j:issn:0253-9624.2006.03.011 article EN 2006-05-01

Prenatal exposure to second-hand smoke (SHS) is associated with increased neurodevelopmental problems in children, however, its impact on the risk of developmental coordination disorder (DCD) preschoolers have not been studied thoroughly. Herein, we probed this association based a nationwide retrospective cohort study 149,005 China. We divided objects into prenatal SHS-exposed group or no exposed (NS-exposed group). Preschoolers were assessed for motor proficiency by Chinese version Little...

10.3389/fpubh.2022.993471 article EN cc-by Frontiers in Public Health 2022-11-08

Previous studies have discovered that zinc-α2-glycoprotein (ZAG) is related to insulin resistance and lipid metabolism. The aim of the study explore change serum ZAG its factors in gestational diabetes mellitus (GDM). Eighty newly diagnosed GDM patients were enrolled case group, 80 normal pregnant women selected as control group. differences baseline data between two groups compared, level relationship with indexes was analyzed. Compared decreased ( <a:math...

10.1155/2021/8879786 article EN cc-by Journal of Diabetes Research 2021-02-18

Background: Scylla paramamosain frequently elicits IgE-mediated type-I hypersensitivity reactions. Molecular candidates for crab allergen-specific immunotherapy (AIT) have not been studied previously. This study aimed to investigate the effects of conformational and linear epitopes on immunoreactivity, produce hypo-immunoreactive derivatives myofibril allergens. Methods: We produced reduced alkylated allergens (alkylation performed using iodoacetamide [IAA]) with destroyed epitopes. also...

10.22541/au.170664493.32313885/v1 preprint EN Authorea (Authorea) 2024-01-30
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