A5100649178- Berberine and alkaloids research
- Advanced Neuroimaging Techniques and Applications
- Clostridium difficile and Clostridium perfringens research
- Antifungal resistance and susceptibility
- Gut microbiota and health
- Antimicrobial Resistance in Staphylococcus
- Pneumocystis jirovecii pneumonia detection and treatment
- Medical Research and Treatments
- Nosocomial Infections in ICU
- Legionella and Acanthamoeba research
- Metabolism and Genetic Disorders
- Synthesis and Biological Activity
- Hydrogen's biological and therapeutic effects
- Motivation and Self-Concept in Sports
- Bacterial biofilms and quorum sensing
- Plant-based Medicinal Research
- Bacterial Identification and Susceptibility Testing
- Infections and bacterial resistance
- Aquatic life and conservation
- Genomics and Rare Diseases
- Respiratory and Cough-Related Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Adolescent and Pediatric Healthcare
- Intraperitoneal and Appendiceal Malignancies
- Genetic Neurodegenerative Diseases
Columbia University Irving Medical Center
2023-2025
National University of Singapore
2022-2025
Binzhou University
2023-2025
Binzhou Medical University
2023-2025
United Imaging Healthcare (China)
2023-2024
Hainan University
2024
Henan Provincial People's Hospital
2022-2023
Zhengzhou University
2022-2023
Guangxi Medical University
2023
Nanjing Medical University
2022
<h3>Importance</h3> It remains unknown whether children born at different degrees of prematurity, early term, and post term might have a higher risk developmental coordination disorder (DCD) compared with completely full-term (39-40 gestational weeks). <h3>Objective</h3> To differentiate between suspected DCD in ages based on national representative sample China. <h3>Design, Setting, Participants</h3> A retrospective cohort study was conducted China from April 1, 2018, to December 31, 2019....
Background Increased rates of methicillin-resistant Staphylococcus aureus (MRSA) antibiotic resistance and the associated morbidity have increased dermatologists' attention to skin soft tissue MRSA infections. However, clinical characterization infections (SSTIs) in Southwest China is lacking, which precludes optimal prevention treatment these Objectives This study was conducted characterize prevalence, comorbidities susceptibility isolates from SSTIs, including community-associated (CA)...
Candida auris is an emerging multidrug-resistant pathogen. Interpretation of susceptibility testing can be difficult since minimum inhibitory concentration (MIC) breakpoints have not been fully established.
Over the last decades, organ transplantation has made rapid progress as a curative therapy for failure. However, adaptive immune system—alloreactive T cells and antibodies targeting human leukocyte antigens (HLA)—is leading cause of graft rejection. The presence anti-donor HLA is considered risk factor that disqualifies particular donor-recipient pair. alloantibodies are found in some long-term survivors, suggesting protective blocking function alloantibodies. Therefore, whether can have...
Wig protectors produced via 3D printing were used in skull protection protocols following decompressive craniotomy (DC) surgery. This study is a single-center, prospective trial involving 25 patients who underwent DC. Patients admitted between February 1, 2023, and June 30, assigned to the control group (receiving standard care), while those July December 31, comprised experimental 3D-printed wig protection). The evaluated participants based on various metrics, including reinjury at site of...
Abstract A simple and rapid method for the simultaneous determination of seven isoquinoline alkaloids, protopine, chelidonine, coptisine, stylopine, sanguinarine, berberine, chelerythrine, in Chelidonium majus L. ( Ch. ) samples by ultra‐performance LC with photodiode array detection is described. The baseline separation these compounds was performed (A) acetonitrile–(B) ammonium acetate (10 mM, adjusted to pH 3.0 acetic acid) as mobile phase using a C18 RP column (2.1×100 mm, 1.7 μm)....
Objective Mitochondrial DNA (mtDNA) depletion/deletions syndrome (MDDS) comprises a group of diseases caused by primary autosomal defects mtDNA maintenance. Our objective was to study the etiology MDDS in 4 patients who lack pathogenic variants known genetic causes. Methods Whole exome sequencing probands performed identify variants. We validated mitochondrial defect analyzing mtDNA, dNTP pools, respiratory chain activities, and GUK1 activity. To confirm pathogenicity deficiency, we...
COVID-19 can be severe in pregnant women, and have adverse consequences for the subsequent infant. We profiled post-infectious immune responses maternal child blood as well breast milk terms of antibody cytokine expression performed histopathological studies on placentae obtained from mothers convalescent antenatal COVID-19. Seventeen mother-child dyads (8 cases 9 healthy unrelated controls; 34 individuals total) were recruited to Gestational Immunity For Transfer (GIFT) study. Maternal...
There are significant differences in the composition of intestinal flora renal transplant recipients before and after an operation, which has a great impact on prognosis transplantation. The purpose this project is to study effect imbalance transplantation.The animal model transplantation was established (mice pretreated with compound antibiotics), or being single antibiotics. HE, PAS, Masson staining used detecting histopathological changes transplanted renal. expression inflammatory...
Purpose: Parkinson’s disease (PD) is a neurodegenerative characterized by progressive loss of dopaminergic neurons in the brain. To achieve better explorations dopamine changes both centrally and peripherally, we employed uEXPLORER dynamic [11C]CFT PET/CT imaging combined with voxel-wise kinetic modeling. Methods: Eleven participants (five patients, PD six healthy volunteers, HC) underwent 75-min scans were enrolled. Volumes interest for four nigrostriatal nuclei (caudate, putamen, pallidum...
Abstract Background Genetic alterations implicated in constitutional disorders range size from single nucleotide substitutions to losses and gains of millions bases. Whole exome sequencing (WES) captures many clinically relevant variants, but an analytic pipeline optimized for detection small substitutions, insertions, deletions may miss pathogenic copy number variants (CNVs). Historically, our laboratory performed separate cytogenetic tests evaluate larger genomic imbalances. Addition...
To investigate photoactivated disinfection (PAD) to treat acute pseudomembranous stomatitis, an animal model was established. Six-week-old male ICR mice were inoculated with Candida albicans under immunosuppression then divided into three groups (15 per group). Pseudomembranous area measured, had 1 mg mL-1 toluidine blue solution spread on the area, left for min (PAD-1 group) or 2 (PAD-2 group), irradiated a 750 mW LED red light min, control group received no treatment. Fungal load measured...
Abstract Despite human saliva representing a convenient and non-invasive clinical substrate for disease diagnosis biomonitoring, its widespread utilization has been hampered by technical challenges. The non-Newtonian, heterogenous highly viscous nature of samples complicate the development automated fluid handling processes that are vital accurate diagnoses. Furthermore, conventional processing methods either resource and/or time intensive precluding certain testing capabilities in low-...
The present study sought to characterise the gut microbiota of subjects with kidney transplantation and healthy control identify distinct analyse their potential function. We found that abundance had significant differences in between two groups. Line Discriminant Analysis (LDA) Effect Size (LEfSe) analysis showed bacterial taxa were differentially represented groups, biomarkers at different taxonomic levels transplant recipients
ABSTRACT Introduction: The sports psychology of athletes and public service policies in various places have been adjusted under the influence epidemic COVID-19. However, team also need adjustments, paucity evidence prevents safe decision-making. Objective: Research current model to outline optimizations during Methods: mechanism athletes’ satisfaction was investigated, mainly involving organizing activities venues, including geographical distribution, technical guidance, health services,...