- Radiopharmaceutical Chemistry and Applications
- Medical Imaging Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Alzheimer's disease research and treatments
- Peptidase Inhibition and Analysis
- Renal cell carcinoma treatment
- Radiomics and Machine Learning in Medical Imaging
- Renal and related cancers
- Cardiomyopathy and Myosin Studies
- Lipid Membrane Structure and Behavior
- Thyroid and Parathyroid Surgery
- Flowering Plant Growth and Cultivation
- Autoimmune and Inflammatory Disorders Research
- Silicon Effects in Agriculture
- Pancreatic and Hepatic Oncology Research
- RNA Interference and Gene Delivery
- Nanoplatforms for cancer theranostics
- Brain Tumor Detection and Classification
- Monoclonal and Polyclonal Antibodies Research
- Thyroid Cancer Diagnosis and Treatment
- Science, Research, and Medicine
- Pediatric health and respiratory diseases
- Environmental and Agricultural Sciences
- Prostate Cancer Treatment and Research
- Erythrocyte Function and Pathophysiology
Renji Hospital
2016-2024
Shanghai Jiao Tong University
2016-2024
Philippine General Hospital
2016
The First Affiliated Hospital, Sun Yat-sen University
2016
Sun Yat-sen University
2016
Shanghai Institute of Hypertension
2016
Ruijin Hospital
2016
Nanjing Drum Tower Hospital
2016
Xinjiang Institute of Water Resources and Hydropower Research
2011
Abstract Accurately predicting and selecting patients who can benefit from targeted or immunotherapy is crucial for precision therapy. Trophoblast cell surface antigen 2 (Trop2) has been extensively investigated as a pan-cancer biomarker expressed in various tumours plays role tumorigenesis through multiple signalling pathways. Our laboratory successfully developed two 68 Ga-labelled nanobody tracers that rapidly specifically target Trop2. Of the tracers, [ Ga]Ga-NOTA-T4, demonstrated...
Abstract Alzheimer's disease (AD) is a common neurodegenerative disease. The histopathological changes in AD include amyloid β‐protein (Aβ) deposition, tau tangles, neuroinflammation, and neurodegeneration. Some of the pathological could be shown vivo by positron emission tomography (PET) magnetic resonance imaging (MRI) biomarkers, which play key role diagnosing AD. Fluorodeoxyglucose (FDG‐PET) can reflect predict dysfunction. Aβ‐PET sensitive for diagnosis early but cannot distinguish...
Pancreatic ductal adenocarcinoma (PDAC) is a malignant tumor with insidious onset, rapid progression, and very poor prognosis. CD47 transmembrane protein associated the development prognosis of pancreatic cancer. The aim this study was to evaluate diagnostic value novel immunoPET tracers targeting in preclinical cancer models. association expression analyzed using Gene Expression Profiling Interactive Analysis platform. Immunohistochemical analysis tissue microarrays performed detect PDAC....
To study whether male sex is a risk factor for prognosis in patients with differentiated thyroid cancer after 131I treatment using the propensity score matching (PSM) method.From April 2016 to October 2021, 1948 postoperative aged 43 (interquartile range: 34, 54) years who received were retrospectively enrolled and divided into (n = 645) female groups 1303). The PSM method was adopted process all data reduce influence of bias confounding variables. Mann-Whitney U test χ2 used analysis....
Objective: To report the baseline data of Chinese patients in PROOF, an ongoing multi-country study evaluating long-term outcomes axSpA patients.Methods: PROOF is a prospective observational (ASAS classification criteria and diagnosed ≤12 months before enrollment) clinical practice over 5 years.Yearly assessments disease activity (BASDAI, ASDAS-CRP), physical function (BASFI), quality-of-life (SF-12v2), productivity (WPAI-SHP), pelvic X-ray (graded by local central readers according to NY...
Alzheimers disease (AD) is a common neurodegenerative disease. The histopathological changes of AD include amyloid β-protein (Aβ) deposition, tau tangles, neuroinflammation and neurodegeneration. Some the pathological could be shown in vivo by positron emission tomography (PET) magnetic resonance imaging (MRI) biomarkers which play key role diagnosing AD. Fluorodeoxyglucose (FDG-PET) can reflect predict dysfunction. Aβ-PET was sensitive for diagnosis early but cannot distinguish severity...
Total variation regularized expectation maximization (TVREM) reconstruction algorithm on the image quality of gallium (68GA) prostate-specific membrane antigen-11 ([68Ga]Ga-PSMA-11) total-body positron emission tomography/computed tomography (PET/CT).Images a phantom with small hot sphere inserts and PET/CT scans 51 prostate cancer patients undergoing [68Ga]Ga-PSMA-11 were reconstructed using TVREM 5 different penalization factors between 0.09 0.45 for 20-, 40-, 60-, 120-, 300-second...
Abstract A 68-year-old man with chest tightness underwent cardiac blood perfusion imaging on total-body 13 N-NH 3 PET/CT. Incidentally, mildly increased activity was observed in the left side of body tongue. Pathological diagnosis proved to be mucosal squamous cell carcinoma.