A5100621632- MicroRNA in disease regulation
- RNA modifications and cancer
- Circular RNAs in diseases
- RNA Interference and Gene Delivery
- RNA Research and Splicing
- Metabolism, Diabetes, and Cancer
- Viral gastroenteritis research and epidemiology
- Peroxisome Proliferator-Activated Receptors
- Heme Oxygenase-1 and Carbon Monoxide
- Plant Gene Expression Analysis
- Viral Infectious Diseases and Gene Expression in Insects
- Lipid metabolism and disorders
- Virus-based gene therapy research
- Advanced biosensing and bioanalysis techniques
- Plant Stress Responses and Tolerance
- Cancer-related gene regulation
- Angiogenesis and VEGF in Cancer
- Drug Transport and Resistance Mechanisms
- Barrier Structure and Function Studies
- Fatigue and fracture mechanics
- Plant biochemistry and biosynthesis
- Bacteriophages and microbial interactions
Affiliated Zhongshan Hospital of Dalian University
2024
Institute of Pomology
2021
Sichuan Agricultural University
2021
First Affiliated Hospital of Kunming Medical University
2020
Kunming Medical University
2020
Innovation Team (China)
2020
First Affiliated Hospital of Zhengzhou University
2019
Xinjiang Uygur Autonomous Region Uygur Medicine Hospital
2017
Institute of Hydrobiology
2005
Chinese Academy of Sciences
2005
Emerging evidence suggests that circular RNAs (circRNAs) are linked to the development and progression of human cancers. Nevertheless, their contribution breast cancer (BC) is still largely unknown. In current study, we screened identified a novel circRNA, circ-UBE2D2, which was highly expressed in BC cell lines tissues closely related aggressive clinical features dismal prognosis. Small interfering RNA (siRNA)–mediated circ-UBE2D2 silencing notably inhibited proliferation, migration...
Double‐stranded RNA (dsRNA) has been shown to be a useful tool for silencing genes in zebrafish ( Danio rerio ), while the blocking specificity of dsRNA is still major concern application. It was reported that siRNA (small interfering RNA) prepared by endoribonuclease digestion (esiRNA) could efficiently silence endogenous gene expression mammalian embryos. To test whether esiRNA work zebrafish, we utilized Escherichia coli RNaseIII digest no tail ntl ) , mesoderm determinant and found...
BACKGROUND: Anthocyanins are not only one of the most important antioxidants in plants but also responsible for coloration strawberry (Fragaria×ananassa), it is suggested to be associated with ascorbic acid (AsA), sugars and plant hormones metabolism. OBJECTIVE: To elucidate molecular differences genes pathways presence absence anthocyanins. METHODS: RNA sequencing (RNAseq) red-fleshed ‘Benihoppe’ its white-fleshed mutant ‘Xiaobai’ was performed. RESULTS: A total 1,156 1,378 transcripts were...
Mounting evidence indicates that circular RNAs (circRNAs) could play a pivotal role in cancers. However, due to the lack of sensitive biomarkers, most lung cancer Xuanwei (LCXW) patients are still diagnosed at an advanced stage accompany with distant metastasis.According LCXW and tissue sources, circRNAs microarray detection was carried out six groups. Considering fold change, raw intensity, length circRNAs, P-value, we selected eightcircRNAs for further study. A total 50 paired tissues were...
To investigate the relationship between gene polymorphism of peroxisome proliferator- activated receptor (PPAR) and susceptibility to northwest dryness syndrome (NDS).The polymorphisms 11 PPARγ loci rs10510418, rs12633551, rs1373640, rs17036188, rs2921190, rs4135247, rs4135275, rs4135283, rs6768587, rs709156, rs7615916 were detected in 249 patients with NDS 260 non-NDS (control group) by using Snapshot single-nucleotide typing technology.All locus detections accordance Hardy-Weinberg...
Objective To construct and identify lentiviral vectors carrying the connexin43(CX43) gene. Methods Plasmids containing CX43 gene were digested using EcoRI/XbaI restriction enzymes, target fragments cloned into lentival to result in recombinant (pHBLV-CMVIE-IRES-ZsGreen-CX43). identified by enzyme digestion electrophoresis, sequencing was carried on only for correct after identification. The successfully-constructed packaging plasmids mixed contransfected 293FT cell producting virus....
Objective To investigate the relationship between expression of vascular endothelial growth factor C (VEGF-C) and receptor-3 (VEGF-R3) in peripheral blood patients with lung cancer pathological characteristics, to assess ability evaluate lymphatic distant metastasis two marks. Methods VEGF-C VEGF-R3 were detected by enzyme-linked immunosorbent assay (ELISA) 124 30 normal controls, used analyze characteristics cancer. Results The serum levels [M(QR)] VEGF-C 283.57 (120.70) pg/ml...