- Cardiac, Anesthesia and Surgical Outcomes
- Acne and Rosacea Treatments and Effects
- Hospital Admissions and Outcomes
- Bariatric Surgery and Outcomes
- Respiratory viral infections research
- Trauma and Emergency Care Studies
- Emergency and Acute Care Studies
- Retinoids in leukemia and cellular processes
- Hip and Femur Fractures
- Enhanced Recovery After Surgery
- Pulmonary Hypertension Research and Treatments
- Influenza Virus Research Studies
- Healthcare Policy and Management
- Pharmaceutical Practices and Patient Outcomes
- Healthcare Systems and Practices
- Frailty in Older Adults
- Travel-related health issues
- Disaster Response and Management
- Medication Adherence and Compliance
- Sepsis Diagnosis and Treatment
- Healthcare Operations and Scheduling Optimization
- Data-Driven Disease Surveillance
- Climate Change and Health Impacts
- High Altitude and Hypoxia
- Reproductive Health and Contraception
Université Claude Bernard Lyon 1
2016-2025
Hospices Civils de Lyon
2016-2025
Health Services and Performance Research Laboratory
2016-2025
Inserm
2021-2025
Research on healthcare performance
2018-2023
Santé Publique France
2023
Centre Hospitalier Régional et Universitaire de Nancy
2019
Hôpital Femme Mère Enfant
2018
Novem (Netherlands)
2018
Brigham and Women's Hospital
2014-2018
Objective: Matching healthcare staff resources to patient needs in the ICU is a key factor for quality of care. We aimed assess impact staffing-to-patient ratio and workload on mortality. Design: performed multicenter longitudinal study using routinely collected hospital data. Setting: Information pertaining every eight ICUs from four university hospitals January December 2013 was analyzed. Patients: A total 5,718 inpatient stays were included. Interventions: None. Measurements Main Results:...
OBJECTIVE Contact patterns and microbiological data contribute to a detailed understanding of infectious disease transmission. We explored the automated collection high-resolution contact by wearable sensors combined with virological investigate influenza transmission among patients healthcare workers in geriatric unit. DESIGN Proof-of-concept observational study. Detailed information on were collected over 12 days. Systematic nasopharyngeal swabs taken, analyzed for A B viruses real-time...
Despite the French pregnancy prevention program (PPP), a considerable number of pregnancies are potentially exposed to oral isotretinoin. New measures were taken by Medicines Agency, including restriction initial isotretinoin prescriptions dermatology specialists in May 2015 and new information campaign on teratogenicity January 2019.
The coronavirus disease 2019 (COVID-19) pandemic disrupted care organization in France, likely changing the use of oral isotretinoin and worsening noncompliance with recommendations. We described number dispensations isotretinoin, teleconsultation, recommendations, before during COVID period. This nationwide cohort included all subjects dispensation between 2022, using data from French Health Data System (SNDS). pre-COVID period corresponded to 2019, 2020, 2021, 2022. first lockdown took...
Abstract Background The death rate due to suicide in elderly people is particularly high. As part of selective prevention measures for at-risk populations, the WHO recommends training “gatekeepers”. Methods In order assess impact gatekeeper members staff, we carried out a controlled quasi-experimental study over course one year, comparing 12 nursing homes where at least 30% staff had undergone with without trained staff. We collected data about residents considered be suicidal, their...
Objective To identify the determinants of operative time for thyroidectomy and quantify relative influence preoperative intra-operative factors. Background Anticipation is key to avoid both waste hospital resources dissatisfaction surgical staff. Having an accurate anticipated planning would allow a rationalized operating room use may improve patient flow staffing level. Methods We conducted prospective, cross-sectional study between April 2008 December 2009. The 3454 patients who underwent...
Pulmonary arterial hypertension (PAH) may lead to right heart failure and subsequently alter glomerular filtration rates (GFR). Chronic kidney disease (CKD, GFR <60 mL/min/1.73 m2) also adversely affect PAH prognosis. This study aimed assess how hemodynamics was associated with reduced estimated (eGFR) the association of CKD survival in patients.In a prospective cohort (2003-2012), invasive eGFR were collected at diagnosis (179 patients) during follow-up (159 patients). The prevalence...
High-fidelity simulation is known to improve participant learning and behavioral performance. Simulation scenarios generate stress that affects memory retention may impact future The authors hypothesized more participants would recall three or critical key messages at months when a relaxation break was performed before debriefing of event scenarios.Each resident actively participated in one scenario observed another. Residents were randomized two parallel-arms. intervention 5-min...
Background Quality improvement and epidemiology studies often rely on database codes to measure performance or impact of adjusted risk factors, but how validity issues can bias those estimates is seldom quantified. Objectives To evaluate whether much interhospital administrative coding variations influence a typical (adjusted mortality) potential incentives based it. Design National cross-sectional study comparing hospital mortality ranking simulated pay-for-performance before/after recoding...
Surgical safety during vacation periods may be influenced by the interplay of several factors, including workers' leave, hospital activity, climate, and variety patient cases. This study aimed to highlight an annually recurring peak surgical mortality summer in France explore its main predictors. We selected all elective open procedures performed French hospitals between 2007 2012. variation was analyzed over time relation workers leaving on vacation, volume hospitals, temperature changes....
<b><i>Background:</i></b> Implementation of enhanced recovery after surgery (ERAS) program pancreatic was associated with decreased length stay (LOS). However, there were only retrospective uncontrolled before-after study, and care protocols heterogeneous. We aimed to evaluate the impact ERAS on postoperative outcomes pancreatectomy through a prospective controlled study. <b><i>Methods:</i></b> A before/after study contemporary control group...
Rationale: Nurse-to-nurse familiarity at work should strengthen the components of teamwork and enhance its efficiency. However, impact on patient outcomes in critical care remains poorly investigated. Objectives: To explore role nurse-to-nurse inpatient deaths during ICU stay. Methods: This was a retrospective observational study eight adult academic ICUs between January 1, 2011 December 31, 2016. Measurements Main Results: measured across day night 12-hour daily shifts as mean number...
Objectives: We investigated whether the risk of death among noncoronavirus disease 2019 critically ill patients increased when numerous coronavirus cases were admitted concomitantly to same hospital units. Design: performed a nationwide observational study based on medical information system from all public and private hospitals in France. Setting: Information pertaining every adult ICUs or intermediate care units 641 between January 1, 2020, June 30, 2020 was analyzed. Patients: A total...
SUMMARY During outbreaks of hospital-acquired influenza-like illness (HA-ILI) healthcare workers (HCWs), patients, and visitors are each a source infection for the other. Quantifying effects these various exposures will help improve prevention control HA-ILI outbreaks. We estimated attributability to: (1) exposure to recorded or unrecorded sources; (2) contagious patient HCW; (3) during observable unobservable period and, (4) moment exposure. Among sources, 59% [95% credible interval (CrI)...
Abstract Background The “practice makes perfect” concept considers the more frequent a hospital performs procedure, better outcome of procedure. We aimed to study this by investigating whether patient outcomes improve in hospitals with significantly increased volume high-risk surgery over time and learning effect existed at individual level. Methods included all patients who underwent one 10 digestive, cardiovascular orthopaedic procedures between 2010 2014 from French nationwide database....
The occurrence of communicable diseases (CD) depends on exposure to contagious persons. effects CD are delayed in time and persons remain for several days during which their contagiousness varies. Moreover when multiple exposures occur, it is difficult know associated with the CD. A statistical model at individual level presented estimate risk patients, healthcare settings, observed other patients workers unobserved or unobservable sources. explores effect exposure, source exposure. It was...
Several studies documented declines in treatment adherence with generic forms of oral bisphosphonates osteoporosis compared to branded forms, while others did not support this relation. Our aim was compare medication brand versus bisphosphonates. A new-user cohort study conducted using routinely collected administrative and healthcare data linked at the individual level extracted from a nationwide representative sample French National Healthcare Insurance database. We included all patients...
Mass tourism during winter in mountain areas may cause significant clustering of body injuries leading to increasing emergency admissions at hospital. We aimed assessing if surgical safety and efficiency was maintained this particular context.We selected all open surgery performed French hospitals between 2010 2012. After identifying with volume stays winter, we considered seasonal variations outcomes using a difference-in-differences study design. computed multilevel regressions evaluate...
Abstract The patient transfer from hospitals to followup care and rehabilitation facilities is an important aspect for maintaining the continuity of medical care. In order achieve flexible healthcare within field Internet Vehicles (IoVs) in terms secure ambulance transport, whole organization patients ' discharge should be anticipated, based mostly on a length stay (LOS) given at time inpatient admission. Therefore, prediction LOS has serious impact influx coordination, bed management,...