A5033450071- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Cerebrovascular and Carotid Artery Diseases
- Infective Endocarditis Diagnosis and Management
- Intracranial Aneurysms: Treatment and Complications
- Mechanical Circulatory Support Devices
- Acute Ischemic Stroke Management
- Cardiac pacing and defibrillation studies
- Pharmaceutical Economics and Policy
- Glioma Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Function and Risk Factors
- Nanoplatforms for cancer theranostics
- Vascular Malformations Diagnosis and Treatment
- Multiple Sclerosis Research Studies
- Multiple Myeloma Research and Treatments
- Venous Thromboembolism Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Meningioma and schwannoma management
- Stroke Rehabilitation and Recovery
- Heart Failure Treatment and Management
- Photodynamic Therapy Research Studies
- Cardiac Arrest and Resuscitation
- Radiomics and Machine Learning in Medical Imaging
University of Warwick
2016-2024
Hospices Civils de Lyon
2015-2024
Université Claude Bernard Lyon 1
2013-2024
Matériaux Ingénierie et Science
2015-2024
Centre National de la Recherche Scientifique
2015-2024
Hôpital Edouard Herriot
2019-2024
Institut National des Sciences Appliquées de Lyon
2021
Hôpital Lyon Sud
2012-2018
Hôpital Pierre Wertheimer
2015-2017
Los Angeles Medical Center
2016
In patients who have chronic heart failure with reduced left ventricular ejection fraction, severe secondary mitral-valve regurgitation is associated a poor prognosis. Whether percutaneous repair improves clinical outcomes in this patient population unknown.We randomly assigned had mitral (defined as an effective regurgitant orifice area of >20 mm2 or volume >30 ml per beat), fraction between 15 and 40%, symptomatic failure, 1:1 ratio, to undergo addition receiving medical therapy...
OBJECTIVE Only one phase III prospective randomized study, published in 2006, has assessed the performance of 5-aminolevulinic acid (5-ALA) fluorescence–guided surgery (FGS) for glioblastoma resection. The aim RESECT study was to compare onco-functional results associated with 5-ALA fluorescence and white-light conventional microsurgery patients managed according current standards care. METHODS This a single-blinded involving 21 French neurosurgical centers, comparing FGS care, including...
5-ALA-induced protoporphyrin IX (PpIX) fluorescence enables to guiding in intra-operative surgical glioma resection. However at present, it has yet be shown that this method is able identify infiltrative component of glioma. In extracted tumor tissues we measured a two-peaked emission low grade gliomas and the glioblastomas due multiple photochemical states PpIX. The second peak appearing 620 nm (shifted by 14 from main 634 nm) limits sensibility current methods PpIX concentration. We...
Percutaneous mitral valve repair (pMVR) is a new therapeutic option for regurgitation. Positive preliminary results in non-randomised studies have been published supporting the use of MitraClip system patients with secondary regurgitation (MR) and poor left ventricular (LV) function contraindicated to surgery. The aim MITRA-FR study provide higher level evidence efficacy device this setting.The national, multicentre, investigator-initiated, open-label, randomised trial evaluate benefits...
The medical technology sector is characterised by a constant influx of innovations with the potential to revolutionise patient care. In France, there are several pathways for devices enter market, from diagnosis-related group tariffs reimbursement lists. However, traditional regulatory can delay market access innovative technologies. response, France has established Early Access Programs expedite devices. This paper looks at three these Innovation Funding, introduced in its final version...
The management of gliomas is based on precise histologic diagnosis. tumor tissue can be obtained during open surgery or via stereotactic biopsy. Intraoperative imaging could substantially improve biopsy precision and, ultimately, the extent resection.To show feasibility intraoperative in vivo probe-based confocal laser endomicroscopy (pCLE) and gliomas.In our prospective observational study, 9 adult patients were enrolled between September 2014 January 2015. Two contrast agents used:...
<h3>BACKGROUND AND PURPOSE:</h3> Endovascular coiling of wide-neck intracranial aneurysms is associated with low rates initial angiographic occlusion and high recurrence. The WEB intrasaccular device has been developed specifically for this indication. To date, there no report the long-term follow-up a series patients treated type device, to our knowledge. Our aim was evaluate 1-year results in prospective single-center WEB-Single-Layer (SL) device. <h3>MATERIALS METHODS:</h3> All WEB-SL...