A5087143112- Toxoplasma gondii Research Studies
- Immune Cell Function and Interaction
- IL-33, ST2, and ILC Pathways
- Neonatal Respiratory Health Research
- Health, Nursing, Elderly Care
- Neonatal Health and Biochemistry
- Women's cancer prevention and management
- Adipokines, Inflammation, and Metabolic Diseases
- Sepsis Diagnosis and Treatment
- Education and Public Policy
- Trypanosoma species research and implications
- interferon and immune responses
- Prenatal Screening and Diagnostics
- Cutaneous Melanoma Detection and Management
- Intensive Care Unit Cognitive Disorders
- Acute Kidney Injury Research
- Migration, Racism, and Human Rights
- Healthcare during COVID-19 Pandemic
- Cancer and Skin Lesions
- Herpesvirus Infections and Treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Nonmelanoma Skin Cancer Studies
- Business and Management Studies
- Healthcare Regulation
- Viral Infectious Diseases and Gene Expression in Insects
Universidade do Porto
2016-2024
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2024
Fundação Oswaldo Cruz
2020
As queimaduras são um grave problema de saúde pública, com impactos físicos e emocionais. No Brasil, ocorrem cerca 1 milhão casos anuais, sendo crianças até quatro anos dos grupos mais vulneráveis. Este estudo teve por objetivo avaliar as taxas internações hospitalares na Região Nordeste, identificando estados maior incidência, diferenças entre gêneros desfechos clínicos. Tratou-se epidemiológico descritivo retrospectivo, dados obtidos do Departamento Informática Sistema Único Saúde -...
Domestic dogs are the main reservoir of Leishmania infantum, a causative agent visceral leishmaniasis (VL). The number human disease cases is associated with rate canine infection. Currently available drugs not efficient at treating (CanL) and months after treatment most show relapse, therefore development new or therapeutic strategies should be sought. In CanL, lack ability to mount specific cellular immune response suitable for combating parasite manipulation cytokine signaling pathway has...
Abstract Immune cells resident in adipose tissue have important functions local and systemic metabolic homeostasis. Nevertheless, these immune cell populations remain poorly characterized bovines. Recently, we described diverse lymphocyte subpopulations of Holstein-Friesian cows. Here, aimed at characterising myeloid present bovine using multicolour flow cytometry, sorting histochemistry/immunohistochemistry. Macrophages, CD14 + CD11b MHC-II CD45 cells, were identified mesenteric...
Abstract The importance of immune cells present in the adipose tissue to metabolic homeostasis has been increasingly recognized. Nevertheless, bovines few studies have so far addressed cell populations resident this tissue. Here we developed an eight-colour flow cytometry panel address T bovine Our results showed that γδ cells, CD4 + and CD8 CD3 non-γδ as well NK are mesenteric subcutaneous Holstein-Friesian cows. frequency both was found higher than majority presented a CD45RO CD62L −...
Abstract Aims Pregnant BALB/c mice infected with a Toxoplasma gondii type II strain were used to determine how pregnancy interferes the development of maternal immunity T and infection disrupts foetal development. Methods Maternal parasite loads assessed by amplification SAG1 using qPCR. Adverse effects evaluated on foetal‐placental quantification implantation units undergoing resorption histopathological analyses. Serum progesterone levels quantified immunoassay. The effect was determined...
BACKGROUND: Acute kidney injury (AKI), an abrupt decline in function, is a challenging diagnosis among preterm infants due to some specific features of this population. The aim study was determine the risk factors developing AKI and predictive for its severity neonates with less than 31 weeks gestational age.METHODS: All age, admitted our NICU between January 2012 December 2015, were included. Maternal neonatal records about demographics, placental abnormalities, perinatal period evolution...
O melanoma do trato urogenital é raro, representando menos de 0,1% dos casos melanoma. Atualmente, a literatura descreve apenas 220 peniano, mais comumente localizado na glande. principal desafio no além determinar origem cutânea ou mucosa, deteção precoce. A doença aparece como uma lesão indolor e pigmentada, crescimento gradual posterior ulceração. Descrevemos o caso um doente 76 anos, que recorreu ao serviço urgência por fleimão escrotal esquerdo, com da uretra peniana suspeita associada...
Intrauterine growth restriction (IUGR) is caused by fetal below what normal for its genetic potential. Recent studies have shown a distinct association between changes in umbilical artery flow IUGR subjects and an increased risk of respiratory morbidity consequently, higher mortality. The aim this study was to find the impact on outcomes premature neonates born with less than 32 weeks gestational age.This retrospective cohort targeted infants gestation, admitted at NCIU, January 2010...
In bovines few studies addressed the contribution of adipose tissue to host immune response infection. Here we evaluated in vitro bovine stromal vascular fraction (SVF) cells protozoan parasite Neospora caninum, using live and freeze-killed tachyzoites. Live N. caninum induced production IL-6, IL-1β IL-10 by SVF isolated from subcutaneous (SAT), while mesenteric (MAT) cell cultures only was increased, showing slight distinct responses between depots. Whereas a clear IL-8 increase detected...
A colelitíase é definida como a presença de cálculos nas vias biliares, formados partir um desequilíbrio nos componentes da bile. complicação mais frequentemente associada esse quadro colecistite, caracterizada pela migração e impactação dos no ducto cístico, sendo uma causa recorrente hospitalizações por sintomas gastrointestinais.
Neospora caninum is an apicomplexan parasite that in cattle assumes particular importance, as it responsible for abortions reported worldwide. Leptin adipokine mainly secreted by adipocytes, which beside its role maintaining metabolic homeostasis also has important effects both innate and adaptive immunity. In previous work, we showed mice chronically infected with N. had elevated serum leptin levels. Here, sought to assess whether acute infection influenced the production of this well...