A5085405152- Cancer survivorship and care
- Health Systems, Economic Evaluations, Quality of Life
- Economic and Financial Impacts of Cancer
- Palliative Care and End-of-Life Issues
- Radiomics and Machine Learning in Medical Imaging
- Glioma Diagnosis and Treatment
- Image and Signal Denoising Methods
- Colorectal Cancer Screening and Detection
- Frailty in Older Adults
- Breast Cancer Treatment Studies
- Cancer-related cognitive impairment studies
- Multiple and Secondary Primary Cancers
- Cancer Treatment and Pharmacology
- Optical Network Technologies
- Advanced Photonic Communication Systems
- Childhood Cancer Survivors' Quality of Life
- Global Cancer Incidence and Screening
- Advanced Optical Network Technologies
- AI in cancer detection
- Lung Cancer Treatments and Mutations
- Prostate Cancer Diagnosis and Treatment
- Digital Media Forensic Detection
- Blind Source Separation Techniques
- Advanced Image Processing Techniques
- Digital Radiography and Breast Imaging
Fondazione Edmund Mach
2025
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2023-2025
European Organisation for Research and Treatment of Cancer
2013-2025
University of Milan
2023-2025
University of Perugia
2007-2024
The University of Texas MD Anderson Cancer Center
2015
Medisch Centrum Haaglanden
2015
University of Freiburg
2015
University Hospital Magdeburg
2015
University of British Columbia
2009-2015
The National Cancer Institute’s Common Terminology Criteria for Adverse Events (NCI-CTCAE) reporting system is widely used by clinicians to measure patient symptoms in clinical trials. European Organization Research and Treatment of Cancer's Quality Life core questionnaire (EORTC QLQ-C30) enables cancer patients rate their related quality life. We examined the extent which clinician symptom scoring agreement could contribute estimation overall survival among patients. analyzed baseline data...
BACKGROUND The objective of this study was to examine the prognostic value baseline health‐related quality life (HRQOL) for survival with regard different cancer sites using 1 standardized and validated patient self‐assessment tool. METHODS In total, 11 pooled from 30 European Organization Research Treatment Cancer (EORTC) randomized controlled trials were selected study. For each site, univariate multivariate Cox proportional hazards modeling used assess ( P < .05) 15 HRQOL parameters...
The purpose of this study was to compare the diagnostic accuracy digital mammography with that screen-film in concurrent cohorts participating same population-based screening program.In a retrospective covering 2004-2005, we compared two women 50-69 years old program operated from mobile units. Each cohort had 14,385 participants matched by age and interpreting radiologist all consecutively registered. We recall cancer detection rates.The rate higher for (4.56% vs 3.96%, p = 0.01),...
The 5th EORTC Quality of Life in Cancer Clinical Trials Conference presented the current state quality life and other patient-reported outcomes (PROs) research from perspectives researchers, regulators, industry representatives, patients patient advocates health care professionals. A major theme was assessment burden cancer treatments, this discussed terms regulatory challenges using PRO assessments clinical trials, patients' experiences innovative methods standardisation research, across...
Olive pomace is a major waste product of olive oil production but remains rich in polyphenols and fibres. We measured the potential an pomace-enriched biscuit formulation delivering 17.1 ± 4.01 mg/100 g hydroxytyrosol its derivatives, to modulate composition metabolic activity human gut microbiota. In double-blind, controlled parallel dietary intervention 62 otherwise healthy hypercholesterolemic (total plasma cholesterol 180–240 mg/dl) subjects were randomly assigned eat 90 (olive-enriched...
We assessed the correlation between quantitative results of immunological faecal occult blood testing (I-FOBT) and colonic lesions (191 colorectal cancers, 890 adenomas) detected at colonoscopy in 2597 FOBT+ (cutoff 100 ng ml(-1) Hb) subjects. At univariate analysis, a higher average Hb content was significantly associated with male gender (P=0.003), age (P=0.02), findings (P=0.000). Among adenomas, size (P=0.0000), presence severe dysplasia (P=0.0001), villous component (P=0.0002), location...
Symptom management in glioma patients remains challenging, as suffer from various concurrently occurring symptoms. This study aimed to identify symptom clusters and examine the association between these patients' functioning.Data of CODAGLIO project was used, including individual patient data previously published international randomized controlled trials (RCTs) patients. prevalence level functioning were assessed with European Organisation for Research Treatment Cancer (EORTC) quality life...
The European Society for Medical Oncology-Magnitude of Clinical Benefit Scale (ESMO-MCBS) has been developed to grade clinical benefit cancer therapies. Improvement in quality life (QoL) is considered relevant, especially the non-curative setting. This reflected by an upgrade preliminary ESMO-MCBS score if QoL improved compared control arm or a downgrade improvement progression-free survival not paralleled overall survival. Given importance final score, need ensure robustness data was...
Background There is currently a lack of consensus on how health-related quality life and other patient-reported outcome measures in cancer randomized clinical trials are analyzed interpreted. This makes it difficult to compare results across controlled (RCTs) synthesize scientific research, use that evidence inform product labeling, guidelines, health policy. The Setting International Standards Analyzing Patient-Reported Outcomes Quality Life Endpoints Data for Cancer Clinical Trials...
In this paper, we apply Bayesian blind source separation (BSS) from noisy convolutive mixtures to jointly separate and restore images degraded through unknown blur operators, then linearly mixed. We found that problem arises in several image processing applications, among which there are some interesting instances of document analysis. particular, the mixture model is proposed for describing multiple views documents affected by overlapping two or more text patterns. consider different...
Introduced to improve the spectral efficiency, time-frequency packing technique allows exploitation of different code rates, leading levels utilization and all-optical reach. To ensure quality transmission optical signal, opto-electronic regeneration must be used propagate beyond maximum reach can inherently offer conversion spectrum rate. In this way, multiple rates enabled in networks, a flexible design which properly optimized traded. This paper addresses for first time joint problem...