A5014289592- Chronic Disease Management Strategies
- Cardiovascular Function and Risk Factors
- Diabetes Management and Education
- Antiplatelet Therapy and Cardiovascular Diseases
- Autoimmune and Inflammatory Disorders Research
- Medical Coding and Health Information
- Sleep and related disorders
- Pancreatic function and diabetes
- Advanced MRI Techniques and Applications
- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Inflammatory mediators and NSAID effects
- Metabolism and Genetic Disorders
- Multiple Sclerosis Research Studies
- Nitric Oxide and Endothelin Effects
- Cardiac electrophysiology and arrhythmias
- Atherosclerosis and Cardiovascular Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Electron Spin Resonance Studies
- Diet and metabolism studies
University of Padua
2020-2022
University of Oxford
2021
Magna Graecia University
2014-2017
In diabetic patients, heart failure with predominant left ventricular (LV) diastolic dysfunction is a common complication for which there no effective treatment. Oxidation of the NOS (nitric oxide synthase) cofactor tetrahydrobiopterin (BH4) and dysfunctional activity have been implicated in pathogenesis vascular cardiomyopathic phenotype.Using mice models human myocardial samples, we evaluated whether by mechanism increasing BH4 availability prevented or reversed LV induced diabetes.In...
Current guidelines suggest the use of low doses acetylsalicylic acid (ASA) for patients with diabetes mellitus (DM) in primary prevention. However, evidences demonstrating beneficial effect ASA prevention are conflicting. In this pilot study, we evaluated a group diabetic patients, prevention, impact treatment on oxidative stress and vascular function. We enrolled 22 newly diagnosed without any previous clinical evidence cardiovascular disease, to receive, (100 mg/daily). tested, basal...
Ensuring multiple sclerosis (MS) patients’ adherence to therapy is often challenging, but it crucial their survival and health-related quality of life (HRQoL). The aim the present study was outline connections between adherence, physical mental HRQoL, levels psychological readiness engage in a treatment, social support, anthropometric, socio-demographic clinical factors patients suffering from MS. This cross-sectional involved sample 237 Italian MS patients. A survey conducted with...
The Mediterranean diet (MD) contributes to preventing numerous chronic diseases and has benefits on cognitive development. Adherence the MD is associated with sleep quality duration in adults adolescents, but this association seems have been little investigated primary-school children. aim of cross-sectional study was verify whether good adherence MD.The enrolled a sample Italian primary school Their mothers were asked answer an anonymous, self-administered questionnaire investigating...
Background: The worldwide prevalence of obstructive lung disease (OLD) is increasing, especially among people > 65 years old, and nearly three in four adults with OLD have two or more comorbid conditions. This study describes the impact such comorbidities on healthcare service usage related costs a country universal health coverage, basing large cohort elderly patients employing real-world data. Methods: We carried out retrospective population (age 64 years) served by Local Health Unit...
Abstract Background The worldwide prevalence of diabetes mellitus is increasing, which especially involves people aged >65 years. A recent study also found that almost 75% adults with have two or more comorbid conditions. aim the was to investigate impact comorbidities on health care service use and costs an elderly cohort high needs (HHCN), based real-world data. Methods For purposes present study, a diagnosis diabetes, residing in area served by ex-ULSS4-Veneto LHU, characterized as...
<h3>Introduction</h3> In the presence of diabetes (DM), myocardial glucose uptake and glycolysis are impaired heart rapidly adapts to use exclusively fatty acids (FA) for ATP generation. This maladaptation is believed play a key role in development cardiomyopathy over time. Here, we show that stimulating nitric oxide synthase (NOS) activity sufficient alleviate metabolic inflexibility, improve energy metabolism prevent LV dysfunction DM by increasing insulin-independent transport....