- Vaccine Coverage and Hesitancy
- Global Maternal and Child Health
- Colorectal Cancer Screening and Detection
- Global Health Care Issues
- Pharmaceutical Economics and Policy
- Viral gastroenteritis research and epidemiology
- Healthcare Systems and Reforms
- CRISPR and Genetic Engineering
- Toxoplasma gondii Research Studies
- RNA and protein synthesis mechanisms
- SARS-CoV-2 detection and testing
- Hepatitis Viruses Studies and Epidemiology
- Herpesvirus Infections and Treatments
- COVID-19 epidemiological studies
- Rabies epidemiology and control
- Healthcare Policy and Management
- Genetic factors in colorectal cancer
- COVID-19 diagnosis using AI
- Insect symbiosis and bacterial influences
- Health Systems, Economic Evaluations, Quality of Life
- Gastric Cancer Management and Outcomes
- Global Cancer Incidence and Screening
- Religious, Philosophical, and Educational Studies
- Global Educational Policies and Reforms
- Microplastics and Plastic Pollution
New York City Department of Health and Mental Hygiene
2024-2025
Centers for Disease Control and Prevention
2024-2025
Minnesota Department of Health
2022-2024
University of Minnesota
2022-2024
University of Georgia
2017-2023
Colorado School of Public Health
2023
Hospice UK
2023
Johns Hopkins University
2019-2022
University of Chicago
2020-2021
University of York
2021
Despite their critical role in chronic toxoplasmosis, the biology of Toxoplasma gondii bradyzoites is poorly understood. In an attempt to address this gap, we optimized approaches purify tissue cysts and analyzed replicative potential within these cysts. order quantify individual cysts, have developed imaging software, BradyCount 1.0, that allows rapid establishment bradyzoite burdens imaged optical sections purified While general larger contain more bradyzoites, relative "occupancy" was...
Estimating the value of global investment in immunization programs is critical to helping decision makers plan and mobilize allocate resources required realize their full benefits. We estimated economic benefits using cost-of-illness value-of-a-statistical-life approaches combined this estimation with program costs derive return on from against ten pathogens for ninety-four low- middle-income countries period 2011–30. Using approach, one dollar invested our was 26.1 2011 2020 19.8 2021 2030....
There is a broad literature suggesting that cognitive difficulties are associated with violence across variety of groups. Although neurocognitive and social deficits core features schizophrenia, evidence relationship between impairments within this patient population has been mixed. We prospectively examined whether neurocognition cognition predicted inpatient amongst patients schizophrenia schizoaffective disorder (n = 89; 10 violent) over 12 month period. Neurocognition were assessed using...
Background: This study seeks to understand the general adult population’s knowledge, attitudes, and stigma towards opioid use disorder (OUD), people with histories of misuse, policies related OUD. Methods: We conducted a cross-sectional national survey U.S. population, using AmeriSpeak’s® web, probability-based panel. The number participants were 947 (493 females 454 males) population adults ages 19 –89 years old who completed self-report covering: social OUD, policy perceptions OUD as...
CRISPR-Cas adaptive immune systems are used by prokaryotes to defend against invaders like viruses and other mobile genetic elements. Immune memories stored in the form of 'spacers' which short DNA sequences that captured from added CRISPR array during a process called 'adaptation'. Spacers transcribed resulting (cr)RNAs assemble with different Cas proteins effector complexes recognize matching nucleic acid destroy it ('interference'). Adaptation can be 'naïve', i.e. independent any existing...
The 340B program provides discounts on outpatient drugs to certain hospitals and federally supported clinics (covered entities) that can be used generate revenue fund safety net care. While numerous studies have found no association between care provision for most hospital covered entities, less is known about whether qualified health centers (FQHCs), the largest group of entities after hospitals, use enhance
ObjectivesUnderstanding the level of investment needed for 2021-2030 decade is important as global community faces next strategic period vaccines and immunization programs. To assist with this goal, we estimated aggregate costs programs ten in 94 low- middle-income countries from 2011 to 2030.MethodWe calculated vaccine, delivery stockpile leveraging latest available data sources. We conducted scenario analyses vary assumptions about relationship between cost coverage well vaccine prices...
Wastewater-based surveillance is an important tool for monitoring the COVID-19 pandemic. However, it remains challenging to translate wastewater SARS-CoV-2 viral load infection number, due unclear shedding patterns in and potential differences between variants. We utilized comprehensive data estimates of prevalence (i.e., source shedding) available New York City (NYC) characterize fecal pattern over multiple waves. collected measurements NYC during August 31, 2020 – 29, 2023 (N = 3794...
Following a call from the World Health Organization in 2017 for methodology to monitor immunization coverage equity line with 2030 Agenda Sustainable Development, this study outlines standardized approach measuring multivariate vaccine coverage, economic impact, and health outcomes. The Vaccine Economics Research Sustainability & Equity (VERSE) composite vaccination measurement is derived literature on of socioeconomic inequality combined measures direct unfairness healthcare access. final...
This cross-sectional study assesses the increases and decreases over time in number of pharmacy contracts, distance from contracting pharmacies, proportion contracts with safety-net practices US.
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been widespread since 2020 and will likely continue to cause substantial recurring epidemics. However, understanding the underlying infection burden (i.e., including undetected asymptomatic/mild infections) dynamics, particularly late 2021 when Omicron variant emerged, is challenging due potential for asymptomatic repeat SARS-CoV-2 infection, changes in testing practices, disease reporting. Here, we leverage...
Abstract Internationally, occupational therapists have recognized the need to provide culturally appropriate services for indigenous people. This study explored experiences, perspectives and practical strategies of working with Aboriginal Torres Strait Islander people living in rural remote areas Queensland, Australia. Semi‐structured interviews were conducted eight who had at least 12 months' experience providing health, rehabilitation or education services. Key themes identified data...
Abstract The protozoan parasite Toxoplasma gondii is capable of infecting all warm‐blooded animals and humans. Infectious, transmissible forms the include oocysts produced by sexual cycle within definitive feline host tissue cysts that form in central nervous system muscle during asexual chronically infected hosts. These are populated with slow‐growing bradyzoites, which until recently have been thought to be dormant entities context immune sufficiency. Reactivation active growth suppression...
Abstract Disruptions in routine immunization caused by COVID-19 put African countries with large vaccine-preventable disease burdens at high risk of outbreaks. Abbas et al. (2020) showed that mortality reduction from resuming outweighs excess exposure during activities. We leverage these estimates to calculate benefit-cost ratios (BCRs) disrupted and apply cost illness (COI) value statistical life-year (VSLY) approaches estimate the child deaths eight diseases. BCRs were computed for each...
Abstract The 340B program grants eligible healthcare providers (“covered entities”) access to discounted prices for outpatient prescription drugs. Covered entities frequently rely on retail pharmacies (“contract pharmacies”) dispense This analysis describes contract pharmacy participation by ownership: the top four chains, grocery small and institutional independent pharmacies. We find that 71% of in 4 chains were pharmacies, 41% 38% store 22% participated 2022. median number contracts per...
In a 1994 telephone survey, only 13% of 522 adult Hispanic respondents in the Southwest used media as main source information for physicians, while 19% regarding health services. Family and friends were sources. About 75% had family physician with mother (68%) making care decisions family. A large majority said that neither physician's sex, nor race factors choosing physicians.