Nathan S. Upham

ORCID: 0000-0001-5412-9342
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About
Contact & Profiles
Research Areas
  • Evolution and Paleontology Studies
  • Species Distribution and Climate Change
  • Bat Biology and Ecology Studies
  • Wildlife Ecology and Conservation
  • Animal Ecology and Behavior Studies
  • Genetic diversity and population structure
  • Zoonotic diseases and public health
  • Genomics and Phylogenetic Studies
  • Digital Imaging for Blood Diseases
  • COVID-19 diagnosis using AI
  • Primate Behavior and Ecology
  • Botany, Ecology, and Taxonomy Studies
  • Viral Infections and Outbreaks Research
  • Ecology and Vegetation Dynamics Studies
  • Viral Infections and Vectors
  • Paleontology and Evolutionary Biology
  • Ecology and biodiversity studies
  • Animal Virus Infections Studies
  • Biomedical Text Mining and Ontologies
  • Environmental and Biological Research in Conflict Zones
  • Data-Driven Disease Surveillance
  • Environmental DNA in Biodiversity Studies
  • Evolution and Genetic Dynamics
  • Forest Ecology and Biodiversity Studies
  • Forensic and Genetic Research

Arizona State University
2020-2025

Yale University
2015-2022

Meise Botanic Garden
2020-2022

Research Institute for Nature and Forest
2022

University of Turin
2022

EcoHealth Alliance
2022

Ronin Institute
2020-2022

Bucknell University
2020-2022

American Museum of Natural History
2020-2022

University of California, Santa Barbara
2022

Accurate taxonomy is central to the study of biological diversity, as it provides needed evolutionary framework for taxon sampling and interpreting results. While number recognized species in class Mammalia has increased through time, tabulation those increases relied on sporadic release revisionary compendia like Mammal Species World (MSW) series. Here, we present Diversity Database (MDD), a digital, publically accessible, updateable list all mammalian species, now available online:...

10.1093/jmammal/gyx147 article ES Journal of Mammalogy 2017-11-15

Big, time-scaled phylogenies are fundamental to connecting evolutionary processes modern biodiversity patterns. Yet inferring reliable phylogenetic trees for thousands of species involves numerous trade-offs that have limited their utility comparative biologists. To establish a robust timescale all approximately 6,000 living mammals, we developed credible sets capture root-to-tip uncertainty in topology and divergence times. Our "backbone-and-patch" approach tree building applies newly...

10.1371/journal.pbio.3000494 article EN cc-by PLoS Biology 2019-12-04

Evolutionary radiations on continents are less well-understood and appreciated than those occurring islands. The extent of ecological influence species divergence can be evaluated to determine whether a radiation was ultimately the outcome divergent natural selection or else arose mainly by nonecological divergence. Here, we used phylogenetic comparative methods test distinct hypotheses corresponding adaptive nonadaptive evolutionary scenarios for morphological evolution sigmodontine...

10.1111/evo.13155 article EN Evolution 2016-12-27

The extensive postglacial mammal losses in the West Indies provide an opportunity to evaluate extinction dynamics, but limited data have hindered our ability test hypotheses. Here, we analyze tempo and dynamics of using a novel set faunal last-appearance dates human first-appearance dates, demonstrating widespread overlap between humans now-extinct native mammals. Humans arrived four waves (Lithic, Archaic, Ceramic, European), each associated with increased environmental impact. Large-bodied...

10.1146/annurev-ecolsys-110316-022754 article EN Annual Review of Ecology Evolution and Systematics 2017-08-23

To determine the distribution and causes of extinction threat across functional groups terrestrial vertebrates, we assembled an ecological trait data set for 18,016 species vertebrates utilized phylogenetic comparative methods to test which categories habitat association, mode locomotion, feeding best predicted risk. We also examined individual International Union Conservation Nature Red List drivers (e.g., agriculture logging) threatening each determined greatest threats four vertebrate...

10.1111/cobi.13852 article ES Conservation Biology 2021-10-20

Many of Madagascar's unique species are threatened with extinction. However, the severity recent and potential extinctions in a global evolutionary context is unquantified. Here, we compile phylogenetic dataset for complete non-marine mammalian biota Madagascar estimate natural rates extinction, colonization, speciation. We measure how long it would take to restore biodiversity under these rates, "evolutionary return time" (ERT). At time human arrival there were approximately 250 mammals on...

10.1038/s41467-022-35215-3 article EN cc-by Nature Communications 2023-01-10

Tetrapods (amphibians, reptiles, birds, and mammals) are model systems for global biodiversity science, but continuing data gaps, limited standardisation, ongoing flux in taxonomic nomenclature constrain integrative research on this group potentially cause biased inference. We combined harmonised taxonomic, spatial, phylogenetic, attribute with phylogeny-based multiple imputation to provide a comprehensive resource (TetrapodTraits 1.0.0) that includes values, predictions, sources body size,...

10.1371/journal.pbio.3002658 article EN cc-by PLoS Biology 2024-07-11

Echimyidae is one of the most speciose and ecologically diverse rodent families in world, occupying a wide range habitats Neotropics. However, resolved phylogeny at genus-level still lacking for these 22 genera South American spiny rats, including coypu (Myocastorinae), 5 West Indian hutias (Capromyidae) relatives. Here, we used Illumina shotgun sequencing to assemble 38 new complete mitogenomes, establishing Echimyidae, Capromyidae as first major be completely sequenced their mitochondrial...

10.1093/molbev/msw261 article EN Molecular Biology and Evolution 2016-11-18

The Ctenohystrica is one of the three major lineages rodents and contains diverse forms related to gundis, porcupines, guinea pigs. Phylogenetic analyses this group using mitochondrial nuclear gene sequences confirm monophyly infraorder Hystricognathi most its recognized subclades, including both Neotropical caviomorphs African phiomorphs, which are recovered as sister groups. Molecular timetrees calibrated with 22 securely placed fossils indicate that hystricognath superfamilies originated...

10.1111/zoj.12201 article EN Zoological Journal of the Linnean Society 2014-11-27

Rodents make foraging decisions by balancing demands to acquire energy and mates with the need avoid predators. To identify variations in risk of predation, nocturnal rodents may use moonlight as a cue risk. Moonlight avoidance behaviors have been observed many rodent species are widely generalized small mammals. However, most prior studies limited 1 or study site, occurred modified habitats. We evaluated desert activity patterns natural habitats from 1999 2006 at 62 sites across Great Basin...

10.1644/12-mamm-a-076.1 article EN Journal of Mammalogy 2013-02-01

Abstract Aim We test whether geographical variation in the length of appendages rodent species follows predictions Allen's rule (a positive relationship between appendage and temperature) at a broad taxonomic scale (order Rodentia). also applicability this varies based on unit analysis (species or assemblage), examined (tail, hind foot, ear), body size, occupied habitat, range life mode saltatorial ability. Location World‐wide. Time period Current. Major taxa studied Rodents Methods...

10.1111/geb.13198 article EN publisher-specific-oa Global Ecology and Biogeography 2020-10-11

Abstract Pneumocystis jirovecii , the fungal agent of human pneumonia, is closely related to macaque . Little known about other species in distantly mammals, none which are capable establishing infection humans. The molecular basis host specificity remains unknown as experiments limited due an inability culture any vitro. To explore evolutionary adaptations, we have sequenced genomes infecting macaques, rabbits, dogs and rats compared them available humans, mice rats. Complete whole genome...

10.1038/s42003-021-01799-7 article EN cc-by Communications Biology 2021-03-08

Abstract Background The tropical Andes and Amazon are among the richest regions of endemism for mammals, each has given rise to extensive in situ radiations. Various animal lineages have radiated ex after colonizing one these from other: Amazonian clades dendrobatid frogs passerine birds may Andean ancestry, transitions be even more common. To examine biogeographic between regions, we investigated evolutionary history three rodents family Echimyidae: bamboo rats (...

10.1186/1471-2148-13-191 article EN cc-by BMC Evolutionary Biology 2013-09-09

As a periodic assessment of the mammal collection resource, Systematic Collections Committee (SCC) American Society Mammalogists undertakes decadal surveys collections held in Western Hemisphere. The SCC surveyed 429 and compiled directory 395 active containing 5,275,155 catalogued specimens. Over past decade, 43 have been lost or transferred 38 new unsurveyed were added. Growth number total specimens, expansion genomic resource collections, substantial gains digitization web accessibility...

10.1093/jmammal/gyy151 article ES cc-by-nc Journal of Mammalogy 2018-11-08

Genetic diversity is critical for species evolution and their adaptability to global changes, while speciation rate explaining large-scale patterns of richness. Exploring correlates variation in genetic rates across a major interest evolutionary biologists, but these two questions have mostly been investigated independently. Here, we assess the relationship between intra-specific 1897 mammal (~one third total diversity) covering all mammalian orders. We find negative association...

10.1038/s41467-025-56820-y article EN cc-by-nc-nd Nature Communications 2025-02-20

We investigated spatial patterns of evolutionary relatedness and diversification rates to test hypotheses about the historical biogeographic processes underlying radiation Neotropical rats mice (Sigmodontinae, ~400 species). A negative correlation between mean phylogenetic distance rodent assemblages reveals a pattern species co‐occurrence in which closely related are also fastest diversifying ones. Subregions Neotropics occupied by distantly that on average more slowly include Central...

10.1111/ecog.04102 article EN Ecography 2018-09-10

The Mammal Diversity Database (MDD) is an open-access resource providing up-to-date taxonomic, nomenclatural, and geographic data for global mammal species. Since its launch in 2018, the MDD has transformed traditionally static process of updating mammalian taxonomy into regular online releases reflecting latest published research. To build on this foundation, we here present version 2.0 (MDD2), which catalogues 6,759 living recently extinct species, representing net increases 4.1% 24.8%...

10.1101/2025.02.27.640393 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2025-03-03

Of the 116 mammal species present in Greater Antilles at start of Holocene Epoch, only 56 now survive, with more extensive losses (~80%) native lineages sloths, shrews, rodents, and primates than bats (~25%). Native occurrences extinctions are summarized herein for Cuba, Hispaniola, Jamaica, Puerto Rico used to introduce this Journal Mammalogy Special Feature on insular Caribbean mammals. Recent efforts understand extinct extant diversity highlight utility paleobiological perspectives...

10.1093/jmammal/gyx079 article ES Journal of Mammalogy 2017-06-04
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