- Retinal Diseases and Treatments
- Ocular Oncology and Treatments
- Retinopathy of Prematurity Studies
- Retinal and Macular Surgery
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Retinal Imaging and Analysis
- Neonatal Respiratory Health Research
- Ocular Infections and Treatments
- Cancer-related Molecular Pathways
- Neonatal Health and Biochemistry
- Neonatal and fetal brain pathology
- Child Abuse and Related Trauma
- Ocular Disorders and Treatments
- Retinal Development and Disorders
- Vascular Malformations Diagnosis and Treatment
- Brain Metastases and Treatment
- Nonmelanoma Skin Cancer Studies
- Corneal Surgery and Treatments
- Drug-Induced Ocular Toxicity
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Systemic Lupus Erythematosus Research
Emory Eye Center
2016-2025
Emory University
2016-2025
Mayo Hospital
2024
L V Prasad Eye Institute
2024
Foundation Fighting Blindness
2020
Research to Prevent Blindness
2007-2015
Texas Biomedical Research Institute
2000-2009
Molecular Oncology (United States)
2009
Prevent Blindness
2009
Theragenics Corporation (United States)
2007-2008
The Centers for Disease Control and Prevention developed screening diagnostic testing guidelines chlamydia gonorrhea at urethral, rectal, pharyngeal sites men who have sex with (MSM). However, in most clinical settings, rectal chlamydial is not performed MSM, primarily sexually transmitted disease (STD) clinics alone perform routine asymptomatic men.We evaluated the prevalence of gonococcal infections among MSM seen municipal STD clinic gay men's community health center. We also determined...
We executed a genome-wide association scan for age-related macular degeneration (AMD) in 2,157 cases and 1,150 controls. Our results validate AMD susceptibility loci near CFH ( P < 10 −75 ), ARMS2 −59 C2/CFB −20 C3 −9 CFI −6 ). compared our top findings with the Tufts/Massachusetts General Hospital study of advanced (821 cases, 1,709 controls) genotyped 30 promising markers additional individuals (up to 7,749 4,625 controls). With these data, we identified locus TIMP3 (overall = 1.1 × −11...
PurposeTo evaluate the efficacy of a single intravitreal injection rAAV2/2-ND4 in subjects with visual loss from Leber hereditary optic neuropathy (LHON).DesignRESCUE is multicenter, randomized, double-masked, sham-controlled, phase 3 clinical trial.ParticipantsSubjects m.11778G>A mitochondrial DNA mutation and vision ≤6 months onset 1 or both eyes were included.MethodsEach subject’s right eye was randomly assigned (1:1) to treatment (single 9 × 1010 viral genomes 90 μl) sham injection. The...
A unique pigmentary maculopathy was recently described in 6 patients with long-term exposure to pentosan polysulfate sodium (PPS), a long-standing oral therapy for interstitial cystitis.To characterize the characteristics and clinical manifestations of PPS-associated maculopathy.In this multi-institutional case series, medical records who exhibited characteristic setting prior PPS were retrospectively reviewed. Data collected from August 1, 2012, October 2018, data analyzed 2018 January...
Measurable competence derived from comprehensive and advanced training in grading digital images is critical studies using a reading center to evaluate retinal fundus infants at risk for retinopathy of prematurity (ROP). Details certification nonphysician trained readers (TRs) have not yet been described.To describe centralized system ROP by TRs the Telemedicine Approaches Evaluating Acute-Phase Retinopathy Prematurity (e-ROP) Study.Multicenter observational cohort study conducted July 1,...
Age-related changes in the skeleton often lead to an increase susceptibility of bone fracture. The purpose this study was determine whether differences material properties between osteonal and interstitial regions have effect on fracture properties. Parameters such as longitudinal toughness, transverse porosity, microhardness, density, weight fractions mineral organic phases were examined a function age using female baboon femurs. With increasing age, toughness decreased significantly did...
Retinoblastoma (RB) is most often diagnosed with clinical features and not tumor biopsy. This study describes tumor-derived analyte concentrations from aqueous humor (AH) liquid biopsy its use in assays.Case series study.Sixty-two RB eyes 55 children 14 control 12 4 medical centers.This included 128 AH samples including: diagnostic (DX) samples, undergoing treatment (TX), after completing (END), during bevacizumab injection for radiation therapy (BEV). Fourteen-control were analyzed...
The purpose of this study was to explore the relationship between integrity collagen and biomechanical properties bone. In study, age (range, 5-26 years old) gender related changes in cortical bone samples from 33 baboon femurs (15 males 18 females) were examined. percentage denatured determined using a selective digestion technique. fracture toughness, elastic modulus, yield ultimate strength, energy three-point bending configurations. porosity weight fractions mineral organic phase also...
In Brief Purpose: To evaluate the safety and effect of bevacizumab pretreatment on incidence recurrent vitreous hemorrhage visual acuity after vitrectomy for proliferative diabetic retinopathy. Methods: This was a consecutive, retrospective, comparative cohort study. Patients undergoing from September 2006 through November 2007 at Emory Eye Center complications retinopathy were identified reviewed. A total 33 eyes pretreated with 104 untreated observed postoperative final acuity. Results: in...
<h3>Objective</h3> To compare the efficacy of intravitreal bevacizumab plus ablative therapy with alone for Coats' disease. <h3>Methods</h3> A retrospective review all paediatric patients who received treatment disease from a single surgeon (GBH) 1 January 2001 to 31 March 2010 was performed. Ten consecutive as part their were matched 10 treated by macular appearance, quadrants subretinal fluid, and telangiectasias. Outcomes evaluated number sessions, time full treatment, resolution...