- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Ocular Surface and Contact Lens
- Ocular Diseases and Behçet’s Syndrome
- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- HIV Research and Treatment
- Retinopathy of Prematurity Studies
- Allergic Rhinitis and Sensitization
- Corneal Surgery and Treatments
- Cerebral Venous Sinus Thrombosis
- Urticaria and Related Conditions
- Ophthalmology and Eye Disorders
- HIV/AIDS Research and Interventions
- Vasculitis and related conditions
- Immune Cell Function and Interaction
- Salivary Gland Disorders and Functions
- Neonatal Respiratory Health Research
- Dermatology and Skin Diseases
- HIV-related health complications and treatments
- Cerebrovascular and Carotid Artery Diseases
- Neonatal and fetal brain pathology
- HIV/AIDS drug development and treatment
University of Pennsylvania
2016-2025
Penn Presbyterian Medical Center
2015-2025
Maxwell Technologies (United States)
2019
Drexel University
2018-2019
Ophthalmology Associates (United States)
2018
Georgetown University
2018
University of British Columbia
2018
University of Toronto
2018
University of Washington
2018
SUNY Upstate Medical University
2018
Dry eye disease is a common chronic condition that characterized by ocular discomfort and visual disturbances decrease quality of life. Many clinicians recommend the use supplements n-3 fatty acids (often called omega-3 acids) to relieve symptoms.In multicenter, double-blind clinical trial, we randomly assigned patients with moderate-to-severe dry receive daily oral dose 3000 mg fish-derived eicosapentaenoic docosahexaenoic (active supplement group) or an olive oil placebo (placebo group)....
Knowledge about the variability of measurements using TearLab Osmolarity System is necessary when evaluating clinical utility readings.To examine tear osmolarity measured by in patients with Sjögren syndrome (SS), blepharitis, and control participants.Cross-sectional study at a tertiary care academic center from June 13, 2012, to March 21, 2013. Participants included 74 eyes 37 volunteer sample (18 SS, 11 8 participants) who were evaluated System, 3 consecutive taken 1-minute intervals...
The aim of this study was to examine the relationship among oral contraceptive pill (OCP) use, contact lens wear, and dry eye signs symptoms in healthy young women.Fifty-two women using OCPs 45 not any form hormonal contraception were enrolled. Medical, menstrual, histories obtained assessed Ocular Surface Disease Index (OSDI) Symptom Assessment iN Dry Eye (SANDE) questionnaires. Tear osmolarity testing performed TearLab Osmolarity System.The mean age all subjects 26.0 ± 3.7 years. There no...
The purpose of this study was to report the rate intraocular pressure (IOP) elevation after intravitreal injections anti-vascular endothelial growth factor agents for exudative age-related macular degeneration.Retrospective chart review all patients receiving ranibizumab and/or bevacizumab degeneration from November 2005 June 2010. Delayed ocular hypertension (OHT) defined as either an IOP ≥22 mmHg on 2 consecutive visits (with increase baseline >6 mmHg) or >26 a single visit with...
To assess the relationship between tear osmolarity and dry eye symptoms in patients with diabetes.Fifty diabetes were enrolled. Demographic information past medical history recorded. Symptoms assessed using ocular surface disease index (OSDI). Tear of each was measured TearLab® Osmolarity System.The majority subjects female (76%), African American (56%), and/or had a diagnosis type 2 (82%). The mean ± standard deviation (SD) for age 54.6±13.4, maximum 304.6±12.7 mOsm/L. Men higher than women...
Measurable competence derived from comprehensive and advanced training in grading digital images is critical studies using a reading center to evaluate retinal fundus infants at risk for retinopathy of prematurity (ROP). Details certification nonphysician trained readers (TRs) have not yet been described.To describe centralized system ROP by TRs the Telemedicine Approaches Evaluating Acute-Phase Retinopathy Prematurity (e-ROP) Study.Multicenter observational cohort study conducted July 1,...
The purpose of this study was to investigate the association between gender and primary open-angle glaucoma (POAG) among African Americans assess demographic, systemic, behavioral factors that may contribute differences genders. Primary Open-Angle American Glaucoma Genetics (POAAGG) had a case-control design included 35 years older, recruited from greater Philadelphia, Pennsylvania. Diagnosis POAG based on evidence both glaucomatous optic nerve damage characteristic visual field loss....
Approaches to limiting exposure antiretroviral therapy (ART) drugs are an active area of HIV research. Here we present longitudinal follow-up a randomized, open-label, single-center study the immune, viral, and safety outcomes structured interruptions (TIs) in patients with chronically suppressed HIV-1 infection as compared equal on continuous including final interruption both arms.Forty-two HIV-infected suppressive ART CD4 counts higher than 400 were randomized 1:1 either (1) three...
In Brief Purpose: The purpose of this study was to determine if there is an association between obstructive sleep apnea (OSA) and central serous chorioretinopathy (CSCR). Methods: Patients with CSCR without a history steroid use or secondary retinal disease were matched based on age/gender/body mass index control patients administered the Berlin Questionnaire assess for OSA risk. scored "OSA+" they at "high risk" reported previous diagnosis. Rates OSA+ compared 2 groups, odds ratio its 95%...
The Schirmer test is one of the 2 ocular surface tests included in current classification criteria for Sjögren syndrome (SS). Tear osmolarity may also be a useful diagnosis dry eye disease. purpose this study was to examine relationship between tear osmolarity, I, and symptoms SS.Patients with SS were assessed TearLab Osmolarity System, production testing, Ocular Surface Disease Index (OSDI), discomfort associated each test.Forty-nine patients mean age 53.7 years female (92%) predominance...
Objective: Increased circulating levels of lipopolysaccharide (LPS) have been demonstrated in HIV-1-infected progressors. We investigated the effect antiretroviral therapy (ART) interruptions on plasma LPS levels. Design and methods: Overall, 77 individuals participated this study (51 HIV-positive 26 healthy). Ten out 51 participants were viremic ART-naive patients 41 chronically suppressed ART (three or more drugs, CD4 cell count than 400 cells/μl, HIV-1 RNA less 500 copies/ml for 8 months,...