Qinghua Guan

ORCID: 0000-0001-5438-9232
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About
Contact & Profiles
Research Areas
  • Railway Engineering and Dynamics
  • Civil and Geotechnical Engineering Research
  • Soft Robotics and Applications
  • Mechanical stress and fatigue analysis
  • Modular Robots and Swarm Intelligence
  • Geotechnical Engineering and Underground Structures
  • Railway Systems and Energy Efficiency
  • Advanced Sensor and Energy Harvesting Materials
  • Advanced Materials and Mechanics
  • Micro and Nano Robotics
  • Nanoplatforms for cancer theranostics
  • Transportation Safety and Impact Analysis
  • Prosthetics and Rehabilitation Robotics
  • Molecular Sensors and Ion Detection
  • Karst Systems and Hydrogeology
  • Magnetic Bearings and Levitation Dynamics
  • Hydrogels: synthesis, properties, applications
  • Engineering Applied Research
  • Gear and Bearing Dynamics Analysis
  • Advanced biosensing and bioanalysis techniques
  • Advanced Nanomaterials in Catalysis
  • Adipose Tissue and Metabolism
  • Brake Systems and Friction Analysis
  • Environmental remediation with nanomaterials
  • Sulfur Compounds in Biology

Southwest Jiaotong University
2015-2025

École Polytechnique Fédérale de Lausanne
2023-2025

Shandong Provincial Water Resources Research Institute
2012-2024

Harbin Institute of Technology
2016-2023

Zhengzhou University
2021

Shanghai Jiao Tong University
2017-2020

Ruijin Hospital
2018-2020

Jiangsu Province Hospital
2019

Jimo District Qingdao Hospital of Traditional Chinese Medicine
2018

Queensland University of Technology
2016

Pneumatic artificial muscles (PAMs) are an extensively investigated type of soft actuator. However, the PAM motions have been limited somewhat to uniaxial contraction and extension, restraining development PAMs. Given current strong interest in robotics, PAMs gaining renewed attention due their excellent compliance ease fabrication. Herein, under inspiration elephant trunk, a family bending helical extensile (HE-PAMs)/helical contractile (HC-PAMs) was proposed analyzed. Through both...

10.1089/soro.2019.0079 article EN Soft Robotics 2020-03-04

Experiments were conducted at field sites to investigate the mechanism of polygonal wear electric locomotive wheels. The rule wheels was obtained. Moreover, two on-track tests have been carried out vibration characteristics locomotive's key components. measurement results out-of-round show that most exhibit wear. main centre wavelength in 1/3 octave bands is 200 mm and/or 160 mm. test indicate dominating frequency vertical acceleration measured on axle box approximately equal passing a...

10.1080/00423114.2017.1399210 article EN Vehicle System Dynamics 2017-11-23

This paper presents a detailed investigation of out-of-round electric locomotive wheels through extensive measurement conducted at field sites. More than 2000 wheels, seven types locomotives widely used in China, have been measured since April 2013. The results indicate that two freight traffic suffer serious polygonal wear problems with center wavelengths ranging from 160 to 315 mm. dominating wavelength is 200 Therefore, the investigations are mainly focused on types. other types, which...

10.1177/0954409716668210 article EN Proceedings of the Institution of Mechanical Engineers Part F Journal of Rail and Rapid Transit 2016-09-16

Suburban express railways have developed rapidly in China recent years. One suburban line suffered from serious interior noise issues caused by short-pitch rail corrugation. Field investigations show that corrugation occurred on different track forms. The wavelength of forms is almost the same and dominating wavelengths are 50−63 mm 1/3 octave band, corresponding to passing frequency 630 Hz band. measurements numerical simulations were carried out investigate cause results indicate localized...

10.1080/23248378.2024.2449529 article EN International Journal of Rail Transportation 2025-01-08

Carbody hunting stability has attracted more and attention due to its great influence on the dynamic performance of a railway vehicle. To fully understand correlation between wheel–rail contact relationship carbody an electric locomotive, geometry analysis multi-body dynamics simulation are carried out in this work. The focus is influences track parameters (including rail profile, cant gauge) relationships stability. A group profiles obtained by interpolating standard CHN60 profile worn...

10.1177/09544097221084412 article EN Proceedings of the Institution of Mechanical Engineers Part F Journal of Rail and Rapid Transit 2022-04-23

Abstract The development and use of architectured structures is changing the means by which we design fabricate soft robots. These materials utilize their topology geometry to control physical mechanical structural properties. We propose an structure based on trimmed helicoids that allows for independent regulation bending axial stiffness facilitates tuneability resulting robot Leveraging FEA computational analysis select a provides optimal trade-off between controllability, sensitivity...

10.1038/s44182-023-00004-7 article EN cc-by npj Robotics 2023-10-26

Soft robots equipped with multifunctionalities have been increasingly needed for secure, adaptive, and autonomous functioning in unknown unpredictable environments. Robotic stacking is a promising solution to increase the functional diversity of soft robots, which are required safe human-machine interactions adapting unstructured However, most existing multifunctional limited number functions or not fully shown superiority robotic method. In this study, we present novel strategy,...

10.1089/soro.2022.0104 article EN Soft Robotics 2023-04-19

Trains crashing onto heavy road vehicles stuck across rail tracks are more likely occurrences at level crossings due to ongoing increase in the registration of and these long getting caught traffic after partly crossing boom gate; incidents lead significant financial losses societal costs. This paper presents an investigation dynamic responses trains under frontal collision on trucks obliquely crossings. study builds a nonlinear three-dimensional multi-body model passenger train colliding...

10.1080/00423114.2016.1240811 article EN Vehicle System Dynamics 2016-10-11

Human papillomavirus (HPV) infection may lead to a series of lesions in the cervix. Distributions HPV genotypes reveal that an increased prevalence high-risk (HR-HPV) is positively correlated with severity cervical lesions. Furthermore, persistent HR-HPV associated risk cancer. Considering newly approval vaccine China and distribution, which meaningful for directing efforts vaccination, more detailed understanding distribution critical. This study aimed investigate overall age-specific...

10.1186/s12985-019-1175-z article EN cc-by Virology Journal 2019-05-20

Soft robot are celebrated for their propensity to enable compliant and complex robot-environment interactions. robotic manipulators, or slender continuum structure robots have the potential exploit these interactions new exploration manipulation capabilities safe human-robot However, interactions, perturbations by external forces cause soft deform in an infinite degree of freedom (DOF) space. To control such system, reduced order models needed; typically consider piecewise sections constant...

10.1109/robosoft55895.2023.10121939 article EN 2023-04-03

Fatigue fracture of rail fastening clips is a common failure in metro. In order to clarify the prevailing factors, on-site experiments and simulations are conducted on metro line China reveal relationship between wheel–rail resonance clips. To mechanism clip installed state, vehicle–track coupled dynamics model created together with refined finite element system. Rail irregularities measured account for actual track excitations. The results show that both force displacement increase...

10.1080/23248378.2024.2360478 article EN International Journal of Rail Transportation 2024-05-30

In the clinic, numeration of circulating tumor cells (CTCs) plays a critical role in cancer diagnosis and treatment, but conventional CTC identification counting that rely on specific antibodies to characterize cell's surface antigens are costive with limitations. Importantly, false positive or negative results may occur due high heterogeneity epithelial-mesenchymal transition (EMT) CTCs. Herein we demonstrate novel effective detecting nanoprobe could rapidly respond level endogenous H2O2...

10.1021/acs.analchem.7b00497 article EN Analytical Chemistry 2017-04-22

Ferroptosis is an iron-mediated, caspase-independent pathway of cell death that accompanied with the accumulations reactive oxygen species (ROS) and oxygenases, as well being involved in many other pathophysiological procedures. However, specific rapid monitoring ferroptosis living cells or tissues has not been achieved so far. Herein, a quinoxalinone-based fluorescent probe (termed Quinos-4, QS-4) aromatic thioether moiety was designed for identification. Upon exposing it to high levels ROS...

10.1021/acs.analchem.8b01721 article EN Analytical Chemistry 2018-06-26

Recent developments in soft actuation demand for resilient, responsive materials with locally varying compositions that are sufficiently stiff to exhibit significant forces. Hydrogels inherently certain stimuli. Yet, they typically suffer from a stiffness-toughness compromise such those and show adequate flexibility display limited This can be partially addressed if hydrogels formulated as double networks. However, their involved processing prevents controlled variations the local...

10.1016/j.cej.2023.145433 article EN cc-by Chemical Engineering Journal 2023-08-14

Robotic locomotion has shown substantial advancements, yet robots still lack the versatility and agility by animals navigating complex terrains. This limits their applicability in environments where they could be highly beneficial. Unlike existing that rely on intricate perception systems to construct models of both themselves surroundings, a more bioinspired approach leverages reconfiguration adapt robot’s morphology its environment. Although interest such multimodal, terrain-adaptive is...

10.1126/scirobotics.adp6419 article EN Science Robotics 2025-02-26
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